-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - pain
(moderate SOE).
�» Note: No evidence supporting the effectiveness
and safety of opioids in the long … term is available. … Multidisciplinary rehabilitation†† Usual care or no multidisciplinary
rehabilitation
Pain, function (short-
and long-term … )
2 SRs + to ++ (pain)
+ (function)
��� to
���
Physical therapy Pain, function (short-
and long-term … ) 1 SR + 2 additional RCTs ++
���
Function (short-term) +
Opioids—other§ Placebo Pain, function
(
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
May 01, 2017 - KQ4: What is the evidence that effects measured at the
end of the treatment phase predict long-term … attainment
Social participation
Psychosocial well-being
Psychosocial adaptation
Harms of interventions
Long-term … Evidence that Effects Measured at
the End of Treatment Predict Long-Term
Functional Outcomes
Few studies … little effect on 1
study and linear effect in another); SOE is low given
small sample size and lack of long-term … Few studies provided data on long-term outcomes after
cessation of treatment.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - Dual Therapy Regimens With Pegylated
Interferon and Ribavirin
In lieu of direct evidence on long-term … Long-term clinical
outcomes
No evidence. … Long-term outcome after
interferon therapy in elderly patients with chronic hepatitis C. … Favorable prognosis of
chronic hepatitis C after interferon therapy by long-term cohort
study. … Long-term cohort
study of chronic hepatitis C according to interferon efficacy.
-
effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
January 01, 2010 - Key Questions
KQ1: Among children ages 2-12 with ASD, what are the short and long-term effects of available … KQ4: What is the evidence that effects measured at the end of the treatment phase predict long
term … • Changes in long-term functional outcome areas, including adaptive independence/self care,
academic … as those that occur ≤ 6 months and long-term outcomes as those that
occur >6 months. … following for
ASDs:
o Treatment modality aimed at modifying the core
symptoms of ASD
o Short- and long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
December 09, 2009 - Key Questions
KQ1: Among children ages 2-12 with ASD, what are the short and long-term effects of available … KQ4: What is the evidence that effects measured at the end of the treatment phase predict long
term … • Changes in long-term functional outcome areas, including adaptive independence/self care,
academic … as those that occur ≤ 6 months and long-term outcomes as those that
occur >6 months. … following for
ASDs:
o Treatment modality aimed at modifying the core
symptoms of ASD
o Short- and long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - : The only benefits considered
under this question are improvements in
osteoarthritis symptoms from long-term … an increased risk of serious CV events
(CV death or myocardial infarction) relative to
placebo in a long-term … Remaining Issues
• The CV safety of nonselective NSAIDs has not
been well studied in large, long-term … Large, long-term trials with active and placebo-
controlled arms would be needed to assess the
safety … • Large, long-term trials of the GI and CV safety
associated with full-dose aspirin, salsalate, or
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-disposition-comments.pdf
April 24, 2019 - Development and implementation of a national
telehealth project for long-term care: a preliminary study … We agree that
additional studies may be w arranted in post-acute
long-term care facilities in addition … We agree that
additional studies may be w arranted in post-acute
long-term care facilities in addition … Implementation of
Telemedicine Consultation to Assess Unplanned Transfers in Rural Long-Term Care
Facil … Development and implementation of a national telehealth
project for long-term care: a preliminary study
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-273-anal-cancer-disposition-comments.pdf
August 20, 2024 - • Some reviewers felt that the long-term update (post hoc, secondary analyses) of the
RTOG 9811 … “Long-term comparative effectiveness of MMC versus cisplatin for
non-metastatic SCCA in terms of oncologic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
January 01, 2022 - In
patients with chronic (mainly neuropathic) pain with short-term treatment (4 weeks to
<6 months) … improvements in pain with some cannabis products, but the impact on
moderate or long-term outcomes … Evidence is too limited to
compare effects on serious and long-term harms, even indirectly. … Important limitations include small
sample sizes, lack of evidence for moderate and long-term use, and … specific cannabis-based products available in the United
10
States, studies on long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
January 01, 2012 - Only one surgical treatment (gastric bypass surgery) has definitively demonstrated long-term
efficacy … Food and
Drug Administration (FDA)-approved antiobesity pharmacotherapy available for long-term use … While several experts mentioned the uncertainty of long-
term adverse events as a potential barrier … A majority of experts thought that reducing or eliminating long-term complications from
obesity might … Long-
term weight loss and improvement in glycemic
parameters with low-dose, controlled-release
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
April 01, 2013 - The long-term efficacy of most preventive
pharmacologic treatments is unknown; evidence on improving … The long-term efficacy of
most preventive pharmacologic treatments is unknown. … (I, O)
• What is the long-term (>1 year) effectiveness of pharmacologic treatments for prevention of … Results valid only for populations maintaining long-term treatment regimens. … most drugs
used long term for other conditions.
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Only one surgical treatment (gastric bypass surgery) has definitively demonstrated long-term
efficacy … Food and
Drug Administration (FDA)-approved antiobesity pharmacotherapy available for long-term use … were uncertain regarding long-term safety and efficacy. … However, some
experts expressed concern regarding long-term efficacy and the potential for patients … safety data with new drug applications and committing to long-term postmarket
studies.28,53 Until
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
October 01, 2014 - Key Question 3: Do FGAs and SGAs differ in other short- and long-term outcomes when used in
children … Short-term is defined as outcomes occurring within 6
months; long-term is defined as outcomes occurring … Long-term effects of ADHD medication on adult height:
results from NESARC. … Short-term is defined as outcomes occurring within 6 months; long-term is
defined as outcomes occurring … We found one-long term (72 weeks) RCT
reporting on the maintenance phase (Findling,
2012).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
February 10, 2010 - education, controlling environmental and comorbid
conditions, and adequate pharmacologic therapy (i.e., long-term … parents of children with
asthma have concerns about regular use of medication, including fears of long-term … asthma-specific); acute
asthma exacerbations; reduced use of quick-relief medications or reduced use of long-term … restrictions)
• Quick-relief medications (e.g., short-acting β2-agonists,
anticholinergics)
• Long-term … asthma-specific)
Improved “asthma
control”
Reduced quick-relief
medications
Reduced long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-anticholinergic-medicines_research.pdf
December 01, 2009 - most part, guidelines for chronic obstructive pulmonary disease (COPD)
are based on results of short-term … clinical trials has
been on overall mortality.6,7 These trials have contributed evidence on longer-term … Several short-term clinical trials9-12 and trials of longer than 12
months13,14 have shown tiotropium … was associated
with reduced COPD exacerbations.15 The recently completed Understanding Potential
Long-Term … Long-term
treatment benefits with tiotropium in
COPD patients with and without short-
term bronchodilator
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - The long-term
consequences of SGAs remain largely unknown.10
There is debate surrounding the efficacy … To capture data on long-term serious adverse events, the inclusion criteria have
been modified to include … illness, health-related quality of life, patient satisfaction, health care-system
utilization, and long-term … time, time to discontinuation of
medication (KQ1, KQ2, KQ4, and KQ5); or 3) both intermediate and long-term … term or long-term or
longterm or followup or follow up or follow-
up).mp. and (study or studies or
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-databases-methods_research.pdf
May 01, 2008 - Setting: Community-dwelling and various long-term care (LTC) settings. … Keywords: Dementia, Medications, Community, Long-term care, Prevalence. … Only 12
were conducted in long-term care settings, all nursing homes. … Information for beneficiaries identified as
long-term care facility residents is obtained from facility … Use of olanzapine,
quetiapine, and risperidone was much higher in long-term care facilities (11.9%,
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1306.pdf
June 01, 2013 - In the absence of
randomized controlled trials or long-term outcomes data, some experts were uncertain … Long-term PN can lead to serious side effects
such as liver damage, the risk of which increases the … If teduglutide proves to be generally tolerable in patients with SBS over
the long term, reductions … In the absence of results from randomized or long-term trials, some experts are unsure about the
true … Long-
term outcomes of an endoscopic myotomy for
achalasia: the POEM procedure.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
January 01, 2017 - Ideally, improvements in symptoms
translate to long-term, clinically relevant, positive changes
in … The evidence is less applicable to long-term
outcomes, such as function, long-term quality of life, … The evidence is not applicable to long-term
followup (greater than 2 years). … Long-
term harms are not assessable in short-term studies, and
relying on observational evidence has … • Additional well-designed long-term studies are needed.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - treatment duration (3 to <6
months), intermediate-term treatment duration (6 to <12 months), and long … treatment duration (3 to <6 months),
intermediate-term treatment duration (6 to <12 months), and long-term … Evidence on intermediate- and long-term effects on pain, function, and
quality of life is limited. … Dronabinol is a safe long-term treatment
option for neuropathic pain patients. … treatment duration (3 to
<6 months), intermediate-term treatment duration (6 to <12 months),
and long-term