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Total Results: 1,425 records

Showing results for "long term".

161. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
     January 01, 2012 - Only one surgical treatment has definitively demonstrated long-term efficacy for morbidly obese patients … (gastric bypass surgery), and only one pharmacotherapy is available for long-term treatment of overweight … While several experts mentioned the uncertainty of long-term adverse events as a potential barrier … A majority of experts thought that reducing or eliminating long-term complications from obesity might … Long- term weight loss and improvement in glycemic parameters with low-dose, controlled-release

162. Medical Therapies for Children With Autism Spectrum Disorder—An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
     May 01, 2017 - KQ4: What is the evidence that effects measured at the end of the treatment phase predict long-term … attainment Social participation Psychosocial well-being Psychosocial adaptation Harms of interventions Long-term … Evidence that Effects Measured at the End of Treatment Predict Long-Term Functional Outcomes Few studies … little effect on 1 study and linear effect in another); SOE is low given small sample size and lack of long-term … Few studies provided data on long-term outcomes after cessation of treatment.

163. Hepatitis-C Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
     November 01, 2012 - Dual Therapy Regimens With Pegylated Interferon and Ribavirin In lieu of direct evidence on long-term … Long-term clinical outcomes No evidence. … Long-term outcome after interferon therapy in elderly patients with chronic hepatitis C. … Favorable prognosis of chronic hepatitis C after interferon therapy by long-term cohort study. … Long-term cohort study of chronic hepatitis C according to interferon efficacy.

164. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
     January 01, 2010 - Key Questions KQ1: Among children ages 2-12 with ASD, what are the short and long-term effects of available … KQ4: What is the evidence that effects measured at the end of the treatment phase predict long term … • Changes in long-term functional outcome areas, including adaptive independence/self care, academic … as those that occur ≤ 6 months and long-term outcomes as those that occur >6 months. … following for ASDs: o Treatment modality aimed at modifying the core symptoms of ASD o Short- and long-term

165. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
     December 09, 2009 - Key Questions KQ1: Among children ages 2-12 with ASD, what are the short and long-term effects of available … KQ4: What is the evidence that effects measured at the end of the treatment phase predict long term … • Changes in long-term functional outcome areas, including adaptive independence/self care, academic … as those that occur ≤ 6 months and long-term outcomes as those that occur >6 months. … following for ASDs: o Treatment modality aimed at modifying the core symptoms of ASD o Short- and long-term

166. Disposition of Comments: Comparative Effectiveness Review No. 273_Treatment of Stages I-III Squamous Cell Anal Cancer: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-273-anal-cancer-disposition-comments.pdf
     August 20, 2024 - • Some reviewers felt that the long-term update (post hoc, secondary analyses) of the RTOG 9811 … “Long-term comparative effectiveness of MMC versus cisplatin for non-metastatic SCCA in terms of oncologic

167. FRN 35 - Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
     April 01, 2013 - The long-term efficacy of most preventive pharmacologic treatments is unknown; evidence on improving … The long-term efficacy of most preventive pharmacologic treatments is unknown. … (I, O) • What is the long-term (>1 year) effectiveness of pharmacologic treatments for prevention of … Results valid only for populations maintaining long-term treatment regimens. … most drugs used long term for other conditions.

168. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
     January 01, 2006 - : The only benefits considered under this question are improvements in osteoarthritis symptoms from long-term … an increased risk of serious CV events (CV death or myocardial infarction) relative to placebo in a long-term … Remaining Issues • The CV safety of nonselective NSAIDs has not been well studied in large, long-term … Large, long-term trials with active and placebo- controlled arms would be needed to assess the safety … • Large, long-term trials of the GI and CV safety associated with full-dose aspirin, salsalate, or

169. RESPONSE TO REQUEST FOR WORK ASSIGNMENT (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-anticholinergic-medicines_research.pdf
     December 01, 2009 - most part, guidelines for chronic obstructive pulmonary disease (COPD) are based on results of short-term … clinical trials has been on overall mortality.6,7 These trials have contributed evidence on longer-term … Several short-term clinical trials9-12 and trials of longer than 12 months13,14 have shown tiotropium … was associated with reduced COPD exacerbations.15 The recently completed Understanding Potential Long-Term … Long-term treatment benefits with tiotropium in COPD patients with and without short- term bronchodilator

170. CER 216 Disposition of Comments Report: Telehealth for Acute and Chronic Care Consultations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-disposition-comments.pdf
     April 24, 2019 - Development and implementation of a national telehealth project for long-term care: a preliminary study … We agree that additional studies may be w arranted in post-acute long-term care facilities in addition … We agree that additional studies may be w arranted in post-acute long-term care facilities in addition … Implementation of Telemedicine Consultation to Assess Unplanned Transfers in Rural Long-Term Care Facil … Development and implementation of a national telehealth project for long-term care: a preliminary study

171. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - Only one surgical treatment (gastric bypass surgery) has definitively demonstrated long-term efficacy … Food and Drug Administration (FDA)-approved antiobesity pharmacotherapy available for long-term use … While several experts mentioned the uncertainty of long- term adverse events as a potential barrier … A majority of experts thought that reducing or eliminating long-term complications from obesity might … Long- term weight loss and improvement in glycemic parameters with low-dose, controlled-release

172. Evidence Summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2022 Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
     January 01, 2022 - In patients with chronic (mainly neuropathic) pain with short-term treatment (4 weeks to <6 months) … improvements in pain with some cannabis products, but the impact on moderate or long-term outcomes … Evidence is too limited to compare effects on serious and long-term harms, even indirectly. … Important limitations include small sample sizes, lack of evidence for moderate and long-term use, and … specific cannabis-based products available in the United 10 States, studies on long-term

173. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - Only one surgical treatment (gastric bypass surgery) has definitively demonstrated long-term efficacy … Food and Drug Administration (FDA)-approved antiobesity pharmacotherapy available for long-term use … were uncertain regarding long-term safety and efficacy. … However, some experts expressed concern regarding long-term efficacy and the potential for patients … safety data with new drug applications and committing to long-term postmarket studies.28,53 Until

174. Antipsychotics-Children-Surveillance-150120 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
     October 01, 2014 - Key Question 3: Do FGAs and SGAs differ in other short- and long-term outcomes when used in children … Short-term is defined as outcomes occurring within 6 months; long-term is defined as outcomes occurring … Long-term effects of ADHD medication on adult height: results from NESARC. … Short-term is defined as outcomes occurring within 6 months; long-term is defined as outcomes occurring … We found one-long term (72 weeks) RCT reporting on the maintenance phase (Findling, 2012).

175. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
     February 10, 2010 - education, controlling environmental and comorbid conditions, and adequate pharmacologic therapy (i.e., long-term … parents of children with asthma have concerns about regular use of medication, including fears of long-term … asthma-specific); acute asthma exacerbations; reduced use of quick-relief medications or reduced use of long-term … restrictions) • Quick-relief medications (e.g., short-acting β2-agonists, anticholinergics) • Long-term … asthma-specific)  Improved “asthma control”  Reduced quick-relief medications  Reduced long-term

176. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
     December 01, 2010 - The long-term consequences of SGAs remain largely unknown.10 There is debate surrounding the efficacy … To capture data on long-term serious adverse events, the inclusion criteria have been modified to include … illness, health-related quality of life, patient satisfaction, health care-system utilization, and long-term … time, time to discontinuation of medication (KQ1, KQ2, KQ4, and KQ5); or 3) both intermediate and long-term … term or long-term or longterm or followup or follow up or follow- up).mp. and (study or studies or

177. Future Research Needs for Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), or Direct Renin Inhibitors (DRIs) for Treating Hypertension (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
     March 01, 2012 - Summary of Evidence on Comparative Long-Term Benefits and Harms of ACEIs, ARBs, and DRIs in Patients … If not, then large long-term clinical trial or observational study would be preferable. 2. … Summary of evidence on comparative long-term benefits and harms of ACEIs, ARBs, and DRIs in patients … Relatively few studies assessed these outcomes over the long term. … If not, then large long-term clinical trial or observational study would be preferable 2.

178. Treatment of Dementia Among Community-Dwelling and Institutionalized Medicare Beneficiaries (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-databases-methods_research.pdf
     May 01, 2008 - Setting: Community-dwelling and various long-term care (LTC) settings. … Keywords: Dementia, Medications, Community, Long-term care, Prevalence. … Only 12 were conducted in long-term care settings, all nursing homes. … Information for beneficiaries identified as long-term care facility residents is obtained from facility … Use of olanzapine, quetiapine, and risperidone was much higher in long-term care facilities (11.9%,

179. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - In the absence of randomized controlled trials or long-term outcomes data, some experts were uncertain … Long-term PN can lead to serious side effects such as liver damage, the risk of which increases the … If teduglutide proves to be generally tolerable in patients with SBS over the long term, reductions … In the absence of results from randomized or long-term trials, some experts are unsure about the true … Long- term outcomes of an endoscopic myotomy for achalasia: the POEM procedure.

180. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0161_09-01-2009.pdf
     January 01, 2009 - dyspnea); reduction or elimination of bronchodilator and inhaled steroid use in the short- medium term … ; reduction or elimination of inhaled and oral steroid use in the medium or long term; and improved