-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - DSM-IV =Diagnostic and Statistical Manual of Mental Disorders, 4th edition; f/u = follow-up; LTFU = long-term … National Sample 2012-2016 claims database
United States
Duration: mean NR, all patients identified as long-term … opioid users had ≥90 days Inclusion: Patients ≥65 years on long-term opioid therapy ≥ with new long-term … , short-acting, and short- and long-acting opioids, Daily MME categorized as <20, 20-50, and ≥120 mg … Mean age: 77 years
Race/ethnicity
White: 83%
Black: 10%
Other: 6%
Female: 83% Long-term opioid therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Only one surgical treatment (gastric bypass surgery) has definitively demonstrated long-term
efficacy … Food and
Drug Administration (FDA)-approved antiobesity pharmacotherapy available for long-term use … However, they expressed concerns regarding long-
term safety and efficacy. … However, some
experts expressed concern regarding long-term efficacy and the potential for patients … Some experts
expressed concern about the long-term safety of this intervention, citing the history
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
January 17, 2014 - diabetes mellitus, what is the
comparative effectiveness of treatment options in terms of the following long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-lumbar-spondylolisthesis.pdf
March 01, 2021 - recommended as a supplemental measure to support patient
management and increase understanding of long-term … recommended as a supplemental measure to support patient
management and increase understanding of long-term … recommended as a supplemental measure to support patient
management and increase understanding of long-term … recommended as a supplemental measure to support patient
management and increase understanding of long-term … recommended as a supplemental measure to support patient
management and increase understanding of long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-lumbar-spondylolisthesis.pdf
March 01, 2021 - recommended as a supplemental measure to support patient
management and increase understanding of long-term … recommended as a supplemental measure to support patient
management and increase understanding of long-term … recommended as a supplemental measure to support patient
management and increase understanding of long-term … recommended as a supplemental measure to support patient
management and increase understanding of long-term … recommended as a supplemental measure to support patient
management and increase understanding of long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - Several systematic reviews of oral diabetes medications
shed light on differences in short-term and long-term … To date, no study has evaluated proximal
clinical measures, long-term effects, and adverse events
among … If they could compare the short- and long-term
effects as well as the adverse effects of these
medications … In the absence of compelling evidence from long-term
trials that include assessment of cardiovascular … This study illustrates the
importance of having more long-term followup data on
cardiovascular outcomes
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - percent of all perinatal morbidity
and mortality and are the leading cause
of infant mortality and long-term … However, these groups also note interest
in assessing long-term safety because the
Effective
Health … Long-term effects have not
been well studied. … Across indications, data are
sparse to evaluate influence on near-term and long-term
maternal and infant … Ultimately, providing data to support
choice of an optimal form of progestogen, to determine
whether long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
October 18, 2010 - Therefore, autism as a long-term outcome would
be outside the scope of the current review which specifically … : childhood development,
neurobehavioural testing, long-term lung function, long-term vision, other … long-term outcomes reported in primary studies. … ((long-term adj therapy) or (long-term adj therapies) or (long-term adj therapeutic)
or (long-term adj … treatment*) or (long-term adj management) or (long-term adj
tocoly*) or (longterm adj therapy) or (
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
July 01, 2011 - One study each found no
association between AHI and stroke or long-term
quality of life. … However, no trial reported long-term clinical outcomes,
and compliance with CPAP treatment is poor. … clinical outcomes.
long-term clinical diabetes; Insufficient • There were 4 studies (3 quality A, 1 … quality B) that evaluated
outcomes for other long-term all-cause mortality. … No adverse event with potentially long-
term consequences was reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_consumer.pdf
February 01, 2016 - It can be a long-term or
lifelong condition and could come back after treatment. … Alcohol use disorder can be a long-term condition,
like high blood pressure or asthma. … You may need treatment over
a long period of time. … Remember: Alcohol use disorder can be a long-term or lifelong condition, and it could
come back after … � If the medicine helps, how long will I need to keep taking it?
-
effectivehealthcare.ahrq.gov/sites/default/files/tnd-0855-170515.pdf
April 28, 2017 - we felt would be
most relevant for these four stakeholder groups, including both intermediate and long-term … Outcomes Intermediate outcomes:
Medication adherence
Diet/exercise
Weight loss
Long-term … Glucose levels/glycemic control
Medication adherence
Diet/exercise
Weight loss
Long-term … Mobile phone
messaging for facilitating self-management of long-term illnesses. … Medium-term Health Coaching and Life-
long Monitoring in Diabetes Mellitus (RenewingHealth).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0855-170515.pdf
April 28, 2017 - we felt would be
most relevant for these four stakeholder groups, including both intermediate and long-term … Outcomes Intermediate outcomes:
Medication adherence
Diet/exercise
Weight loss
Long-term … Glucose levels/glycemic control
Medication adherence
Diet/exercise
Weight loss
Long-term … Mobile phone
messaging for facilitating self-management of long-term illnesses. … Medium-term Health Coaching and Life-
long Monitoring in Diabetes Mellitus (RenewingHealth).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
March 05, 2015 - If there are no long-term studies of vitamin E that have
examined liver toxicity, this should be stated … We have added to the ES, “Although evidence
concerning potential long-term benefits are included
as … make clinical and/or policy recommendations to
women trying to determine the overall net effect of long-term … Long term effects of hormone therapy (HT) also were
appropriately identified and reviewed, including … to prove all
of this, and never will be – particularly since questions about chronic
disease and long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - trials, multiple
observational studies; limited
long-term data on serious GI
harms)
Moderate for CV … Other
long-term followup data from randomized trials is
lacking. … CHF = congestive heart failure; CI = confidence interval; CLASS = Celecoxib Long-term Arthritis Safety … Large, long-term trials with active and placebo-
controlled arms would be needed to assess the
safety … • Large, long-term trials of the GI and CV safety
associated with full-dose aspirin, salsalate, or
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
July 01, 2009 - The present review examines the evidence for the short-
and long-term effect and safety of RF catheter … Key Question 1.What is the effect of RFA on
short-term (6 to 12 months) and long-term
(>12 months) rhythm … How does the effect of RFA on
short- and long-term rhythm control differ
among the various techniques … Data from four RCTs did not show
significant differences in long-term rhythm control
comparing 8 mm tip … Key Question 4.What are the short- and long-
term complications and harms associated with
RFA?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
October 01, 2021 - In RCTs (mostly placebo controlled) of patients with chronic (mainly neuropathic)
pain with short-term … Key Question 1: Benefits of cannabinoids for chronic pain compared with placebo in the
short term (4 … in pain with some cannabis products, but the impact on moderate or long-
term outcomes is unknown. … The comparisons of effects on serious and long-
term harms are however not possible, even indirectly. … Important limitations include small sample sizes, lack of
evidence for moderate and long-term use, and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - We
found no differences between groups in missed school/work
or quality of life in the long term (> … We
could not make a conclusion about effects of tonsillectomy on
throat infections in the long term … We found no difference in effects on long-term
(>12 months) persistence of OSDB symptoms, quality of … Furthermore, most available studies provided little to
no long-term clinical outcome data, focusing … Long-term effects
are limited in the literature base, particularly regarding
outcomes that include
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_disposition-comments.pdf
December 20, 2012 - We
modified our future research
recommendation to reduce the
emphasis on long-term outcomes, and … Definitions
are acceptable but I don't think it's reasonable to expect long-
term outcomes from these … We have revised our future research
recommendation to reduce the
emphasis on long-term outcomes in … As stated above, it’s
unrealistic to expect researchers to track long term outcomes
without adequate … We have
revised our recommendations
regarding long-term outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
January 01, 2015 - long-
term clinical outcomes. … *For studies comparing thiazolidinediones with metformin, we reviewed only HbA1c, long-term outcomes, … Comparative effectiveness of sulfonylureas compared with metformin for long-
term all-cause mortality … The comparative long-term benefits and
harms of other diabetes medications remain unclear. … Long-term risk of cardiovascular
events with rosiglitazone: a meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - pain
(moderate SOE).
�» Note: No evidence supporting the effectiveness
and safety of opioids in the long … term is available. … Multidisciplinary rehabilitation†† Usual care or no multidisciplinary
rehabilitation
Pain, function (short-
and long-term … )
2 SRs + to ++ (pain)
+ (function)
��� to
���
Physical therapy Pain, function (short-
and long-term … ) 1 SR + 2 additional RCTs ++
���
Function (short-term) +
Opioids—other§ Placebo Pain, function
(