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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
September 01, 2011 - Key Question 3: What are the short-term and long-
term adverse events associated with specific medical … What are the short-term and
long-term adverse events associated with
specific medical, surgical, and … Administrative databases can
provide additional data for addressing long-term
safety issues. … Short-term and long-term adverse events associated with specific medical, surgical, and newer forms
of … Key Question 3: What are the short-term and long-term adverse events associated with specific medical
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effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-revised-comments.pdf
December 29, 2020 - There were few studies included for long-
term opioid use, mostly because they did not include the specific … Study types that informed long-term data. … term
chronic pain in patients and usually they
are done for a long period of time to get
the whole … Uncontrolled studies that did not
compare long-term use in
persons prescribed versus not
prescribed … The study by Sun et al. does not
meet inclusion criteria because it
does not compare long-term
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveill-report-1.xlsx
September 30, 2015 - DSM-IV =Diagnostic and Statistical Manual of Mental Disorders, 4th edition; f/u = follow-up; LTFU = long-term … National Sample 2012-2016 claims database
United States
Duration: mean NR, all patients identified as long-term … opioid users had ≥90 days Patients ≥65 years on long-term opioid therapy ≥ with new long-term opioid … , short-acting, and short- and long-acting opioids, Daily MME categorized as <20, 20-50, and ≥120 mg … Mean age: 77 years
Race/ethnicity
White: 83%
Black: 10%
Other: 6%
Female: 83% Long-term opioid therapy
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/home-dialysis-ESKD-rapid-research.pdf
April 01, 2025 - Typology of staff-assisted home dialysis: long-term or temporary............................ 5
Figure … This form of
5
assisted home dialysis can be paid or unpaid, temporary or long-term, and can … Typology of staff-assisted home dialysis: long-term or temporary
Background and Context
Back … Of 64 patients who used the staff-assisted PD program during the
pilot year, 53 used it long-term and … Evaluation of a 12-Month Pilot of Long-Term
and Temporary Assisted Peritoneal Dialysis.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
January 01, 2009 - In principle, long-term randomized controlled trials (RCTs) of test-plus-
treatment strategies offer … However, long-term RCTs may not always be
necessary. … Long-term RCTs
will not be necessary if it is valid to use other sources of evidence to address these … However, long-term RCTs comparing test-plus-treatment
strategies may not always be available, feasible … Long-term RCTs are not required if assumptions linking these intermediate
outcomes to long-term patient
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
December 09, 2009 - vision, memory loss or difficulty
concentrating.2
TBIs are associated with a range of short- and long-term … What are the outcomes (short and long term, including harm) of treatment for depression
amongst traumatic … available, which treatment modalities are equivalent or
superior with respect to benefits, short- and long-term … Are the short- and long-term outcomes of treatment for depression after TBI modified by
individual characteristics … after traumatic brain injury:
o Treatment modality
o Symptom management approach
o Short- and long-term
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effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Experts cited the cost, need for daily injections, and unknown long-term safety
profile as potential … Diet and exercise and currently available medications are ineffective in
long-term weight loss. … tolerance is a concern for some, but more importantly there is lack of long-term data to
show any … I
suspect the weight loss is temporary and doesn’t have an effect on long term outcomes. … complications, socio-cultural factors, and high operative and
long-term costs.
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effectivehealthcare.ahrq.gov/products/prosthesis/research
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0210_12-07-2009.pdf
January 01, 2009 - Long-term consequences of these changes can include financial dependence, social
isolation, divorce, … Forms of
rehabilitation to address the long-term outcomes include physical, behavioral, speech, occupational
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0251_05-20-2010.pdf
January 01, 2010 - for prevention and treatment
strategies: effectiveness, benefits, and harms
Setting(s): Hospital or long-term … How can we identify patients at risk for pressure ulcers in the hospital or long-term
care setting
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_surveillance.pdf
May 16, 2013 - How does the effect of RFA on short- and long-term rhythm control differ among the various
techniques … What are the short- and long-term complications and harms associated with RFA? … (6 to 12 months) and long-term (>12 months) rhythm control, rates of congestive heart failure, left … (6 to 12 months) and long-term (>12 months) rhythm control, rates of congestive heart failure, left … (6 to 12 months) and long-term (>12 months) rhythm control, rates of congestive heart failure, left
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
February 01, 2010 - Although the procedures have
been compared in several randomized trials, their long-term effects on … Data for long-term mortality are similar after CABG and PCI in most patient
subgoups with multivessel … Thus, pooled data from ten long-term randomized trials of patients with multivessel
coronary disease … Long-term outcomes of coronary-artery
bypass grafting versus stent implantation. … Comparing long-term survival of patients
with multivessel coronary disease after
CABG or PCI.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_consumer-2016.pdf
January 01, 2016 - education
programs, helped people with type 1 diabetes
better manage their blood sugar in the short
term … More research is needed to know if
behavioral programs help in the long term. … How long would each program
session be? … Having high blood sugar (a condition called
“hyperglycemia”) can cause serious health
issues in the long … term.
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - when clinical trials are lacking; when generalizability is
uncertain; or when investigating rare, long-term … enough in duration to
adequately assess uncommon or long-term harms.
9
Third, most RCTs are explanatory … For example, the Celecoxib Long-term Arthritis Safety Study (CLASS), a major trial of
celecoxib, was … Such studies can
be excluded from CERs if more reliable long-term, comparative data are available. … Celecoxib Long-term Arthritis Safety Study
[see comment].
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - when clinical trials are lacking; when generalizability is
uncertain; or when investigating rare, long-term … enough in duration to
adequately assess uncommon or long-term harms.
9
Third, most RCTs are explanatory … For example, the Celecoxib Long-term Arthritis Safety Study (CLASS), a major trial of
celecoxib, was … Such studies can
be excluded from CERs if more reliable long-term, comparative data are available. … Celecoxib Long-term Arthritis Safety Study
[see comment].
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-241-wheelchair-users-disposition-comments.pdf
October 18, 2022 - The authors address the need for longitudinal outcomes,
however there will likely be no long-term outcomes … lifestyle physical
activity interventions which may
have greater and more sustained
short as well as long … term health
effects." … term health
effects." … More
of an emphasis on long-term follow-up after training, and how
we can measure or quantify positive
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
September 01, 2009 - For patients who require intensive
lipid-modifying therapy, what are the comparative
long-term benefits … Trials of
greater than 24 weeks duration were defined as long
term, while those less than 24 weeks were … Long-Term Benefits and
Serious Adverse Events
There are several important limitations in the evidence … regarding long-term clinical outcomes. … Long-Term Benefits and
Serious Adverse Events
• The comparator for trials of combination therapy
in
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - Delirium experienced during a hospitalization is strongly associated with new or
worsening long-term … Preventive and therapeutic interventions are required to reduce the burden of delirium
and associated long-term … cognitive impairment (Change in cognition after
delirium that has a long-term duration or is possibly … Long-term cognitive impairment
after critical illness. … Does antipsychotic drug use increase the risk of long
term mortality?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/measuring-blood-pressure-future_research.pdf
August 01, 2012 - Effective
treatments for hypertension are available; however, long-term adherence to medication and … optimal control requires long-term monitoring. … This is particularly pertinent, since SMBP requires long-term patient
participation. … , achieving
optimal control requires long-term monitoring. … Background
The SMBP CER identified three related evidence gaps pertinent to long-term followup.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2010_research-protocol.pdf
January 01, 2010 - This requirement raises critical issues related to long-term compliance, safety (risk vs. benefit), and … The long-term use of
Source: www.effectivehealthcare.ahrq.gov
Published Online: August 24, … Short- and long-term efficacy and effectiveness. … Long-term effects of budesonide or nedocromil in children with asthma. … But as effective as they are, rescue medications don't have a long-term effect.