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81. Executive Summary_Systematic Review: Psychosocial and Pharmacologic Interventions for Disruptive Behavior in Children and Adolescents (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-executive-summ.pdf
    April 01, 2025 - Parent-only Intermediate term 6 RCTs Small effect + 6 RCTs Small effect + Parent-only Long … Timeframea ECBI Intensity Scores/ CBCL Externalizing Scores ECBI Problem Scores Multicomponent Long … Parent-only Intermediate term 6 RCTs Small effect + 3 RCTs Moderate effect + Parent-only Long … evidence; ++ = moderate strength of evidence a Short term: ≤24 weeks; intermediate term: 25-47 weeks; long … Because long-term 8 evidence was often lacking or sparse, treatment should include

82. Disposition of Comments: Technical Brief 37 Prevention, Diagnosis, and Management of Opioids, Opioid Misuse, and Opioid Use Disorder in Older Adults (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-37-opiod-use-adults-comments.pdf
    November 03, 2020 - Indeed in some studies of long term opioid use, overdose deaths seem to diminish with age. … Methods Please clarify that you are considering long term opioid therapy as an outcome. … and long-duration opioids and increased likelihood of long-term use. … Long-term opioid; should not be categorized as a negative outcome in itself. … indicator of greater need for long-term use to manage chronic pain.”

83. Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers; Long-Term Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/adhd_disposition-comments.pdf
    October 01, 2011 - But even so, MTA late data are not too supportive of long-term benefits. … Gives equivocal support for long- term use of stimulants. … These issues have significant implications for long-term treatment. … periods of time: how long? … Complicated by the assumption of long-term use as necessary.

84. Long-Term Drug Therapy and Drug Holidays for Osteoporotic Fracture Prevention | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/osteoporosis-fracture-prevention/research-protocol

85. Cannabis-App-F5-Table-Surveillance-Report-2 0 0 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
    May 29, 2025 - frequent cannabis use (≥20 days/mo) B: No cannabis use NR Total: 208 (4 years); yearly assessments Long … cannabis B: Controls who did not receive authorization for medical cannabis A: NR B: NA 78 (20 months) Long … or weekly use of marijuana B: Monthly or 1-2 times a month use of marijuana C: No use NR 52 (1 year) Long … NA 84 (21 months) Long NR None NR NR NR NR NR A vs. … THC 12.5 +/- 1.5% titrated to a max dose of 5 g/day B: Usual care A: Median dose 2.5 g/day B: NA 52 Long

86. Appendix-E-Table-E5 0 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
    May 29, 2025 - frequent cannabis use (≥20 days/mo) B: No cannabis use NR Total: 208 (4 years); yearly assessments Long … cannabis B: Controls who did not receive authorization for medical cannabis A: NR B: NA 78 (20 months) Long … or weekly use of marijuana B: Monthly or 1-2 times a month use of marijuana C: No use NR 52 (1 year) Long … NA 84 (21 months) Long NR None NR NR NR NR NR A vs. … THC 12.5 +/- 1.5% titrated to a max dose of 5 g/day B: Usual care A: Median dose 2.5 g/day B: NA 52 Long

87. Cer-250-Cannabis-2025-Surv-Rep-Update-Table-E5 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-table-e5.xlsx
    January 01, 2025 - frequent cannabis use (≥20 days/mo) B: No cannabis use NR Total: 208 (4 years); yearly assessments Long … CBD dominant C: Prescribed cannabis, THC dominant D: Prescribed cannabis, mixed NR 52 weeks (1 year) Long … acting opioids, OR: 3.090 (95% CI 2.417 to 3.950) Nabiximols vs. long acting opioids, RR: 1.421 (95% … acting opioids, OR: 3.777 (95% CI 2.878 to 4.957) Nabiximols vs. long acting opioids, RR: 1.386 (95% … NA 84 (21 months) Long NR None NR NR NR NR NR A vs.

88. Public-Reporting-Quality-Improvement Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_executive.pdf
    July 01, 2012 - individuals and organizations that provide or arrange care, including individual clinicians, hospitals, long-term … In studies of health plans and long-term care, the outcomes studied most often were quality measures … However, some studies in long-term care have found that public reporting can create incentives that … Studies found no consistent difference across characteristics. 6 Long-term care (6) Low Patient … as increasing disparities or the use of more health services (e.g., more hospital readmissions from long

89. Critical Analysis of the Evidence for Patient Safety Practices in Nursing Home Settings (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/nursing-home-safety_research-protocol.pdf
    July 22, 2015 - level, and 2% were considered to be an actual harm.2 An estimated mean 1.5 falls/bed/year occur in long-term … Differences in setting (acute vs. long-term care), staffing, resources, including health information … Are there important differences in patient safety issues for short-stay versus long-stay residents? … Resident mix, including short and long stay Guiding Question 3: Describe the Current Evidence of the … Long-term Care Services in the United States: 2013 Overview.

90. Cannabis-2023-Surv-Rep-4-Table-E-5 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-table-E-5.xlsx
    January 01, 2023 - frequent cannabis use (≥20 days/mo) B: No cannabis use NR Total: 208 (4 years); yearly assessments Long … or weekly use of marijuana B: Monthly or 1-2 times a month use of marijuana C: No use NR 52 (1 year) Long … acting opioids, OR: 3.090 (95% CI 2.417 to 3.950) Nabiximols vs. long acting opioids, RR: 1.421 (95% … acting opioids, OR: 3.777 (95% CI 2.878 to 4.957) Nabiximols vs. long acting opioids, RR: 1.386 (95% … NA 84 (21 months) Long NR None NR NR NR NR NR A vs.

91. Cannabis-2022-Surv-Rep-4-Table-F5 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-table-F5.xlsx
    January 01, 2022 - frequent cannabis use (≥20 days/mo) B: No cannabis use NR Total: 208 (4 years); yearly assessments Long … or weekly use of marijuana B: Monthly or 1-2 times a month use of marijuana C: No use NR 52 (1 year) Long … acting opioids, OR: 3.090 (95% CI 2.417 to 3.950) Nabiximols vs. long acting opioids, RR: 1.421 (95% … acting opioids, OR: 3.777 (95% CI 2.878 to 4.957) Nabiximols vs. long acting opioids, RR: 1.386 (95% … NA 84 (21 months) Long NR None NR NR NR NR NR A vs.

92. Diabetes Mellitus (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
    September 26, 2014 - The drug intervention combines long- and short-acting insulin. … with long-acting insulins to be an incremental benefit … However, some experts determined the reduced frequency of injecting ultra-long-acting insulins to long-acting … Most experts listed the similarities of care delivery of ultra-long-acting insulins to available long-acting … other long term delivery system available on the market.

93. Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
    April 01, 2013 - Long-term followup. … Long-term followup. … Long-term followup. … Long-term followup. … Long-term followup.

94. Updating the Measurement Criteria for AHRQ’s National Healthcare Quality and Disparities Report (NHQDR) (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/updating-criteria-qdr-protocol-amendment.pdf
    December 28, 2023 - , the possibility of unforeseen adverse effects on vulnerable populations, and how best to achieve long-term … executive-order-on-further-advancing-racial-equity-and-support-for-underserved-communities-through-the-federal-government/#:%7E:text=On%20my%20first%20day%20in,long … executive-order-on-further-advancing-racial-equity-and-support-for-underserved-communities-through-the-federal-government/#:%7E:text=On%20my%20first%20day%20in,long … 20addressing Version 5 4/18/2019 6 through-the-federal- government/#:~:text=On%20my%20first%20day%20in,long … executive-order-on-further-advancing-racial-equity-and-support-for-underserved-communities-through-the-federal-government/#:%7E:text=On%20my%20first%20day%20in,long

95. CER 217 Management of Infertility Evidence Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
    May 01, 2019 - What are the short- and long-term health outcomes of donors in infertility? – KQ 6a. … Do short- and long-term outcomes differ among different stimulation/retrieval protocols? … However, there was a lack of evidence on any long-term outcomes. … The long- term prognosis for live birth in couples initiating fertility treatments. … Long-term relationship of ovulation-stimulating drugs to breast cancer risk.

96. Version-3-Immunity-After-Covid-19-Appendix-Table-B-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19-appendix-table-B-1.xlsx
    January 24, 2022 - United States Retrospective cohort Delta variant analysis: March 9, 2020 – December 31, 2020 Long-term … analysis: 152,656 Total: 477,813 Delta analysis: 50,327 Long-term effectiveness analysis: 11,186 … Delta analysis: 274,830 Long-term effectiveness analysis: 141,417 Delta analysis: 40 Long-term effectiveness … analysis: 81 Delta analysis: 50,287 Long-term effectiveness analysis: 11,105 Delta analysis: 1,494 … Long-term effectiveness analysis: 7,167 Delta analysis: 273,336 Long-term effectiveness: 134,250 Protection

97. Atrial-Fibrillation-Ablation Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_surveillance.pdf
    May 16, 2013 - What is the effect of radiofrequency ablation (RFA) on short- (6 to 12 months) and long- (>12 months … the patient-level and intervention-level characteristics associated with RFA effect on short- and long-term … How does the effect of RFA on short- and long-term rhythm control differ among the various techniques … What are the short- and long-term complications and harms associated with RFA? … PAF (or persistent AF) HR=1.90, 95% CI: 1.00, 3.50 (type of AF - long-standing persistent AF as a

98. Cer-250-Cannabis-2024-Surv-Rep-Update-Table-E5 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-table-e5.xlsx
    January 01, 2024 - frequent cannabis use (≥20 days/mo) B: No cannabis use NR Total: 208 (4 years); yearly assessments Long … or weekly use of marijuana B: Monthly or 1-2 times a month use of marijuana C: No use NR 52 (1 year) Long … acting opioids, OR: 3.090 (95% CI 2.417 to 3.950) Nabiximols vs. long acting opioids, RR: 1.421 (95% … acting opioids, OR: 3.777 (95% CI 2.878 to 4.957) Nabiximols vs. long acting opioids, RR: 1.386 (95% … NA 84 (21 months) Long NR None NR NR NR NR NR A vs.

99. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting_research-protocol.pdf
    August 19, 2011 - could diagnose patients who have coronary stenoses that might otherwise be missed, thereby improving long … generate additional unnecessary invasive tests or unnecessary treatments that can adversely impact long … their effects on the diagnostic thinking and therapeutic decisionmaking, short-term outcomes, and long-term … ischemic or nonischemic ○ Left main artery lesions ○ Any type of complex coronary lesions (e.g., long … Impact of intravascular ultrasound-guided stenting on long-term clinical outcome: a meta-analysis of

100. Menopause Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - Key Question 3 was a two-part question examining adverse events and long- term effects of nonhormone … The picture of long-term effects emerges with some clarity, as summarized in Table G. … Although no salient long term benefits were identified, neither were safety signals apparent. … Summary of long-term effects of nonhormone therapy preparations Outcome Risk Treatment vs. … Estrogens are accompanied by potential long-term harms that require consideration.