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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
    July 01, 2024 - Of 39 high, serious, or critical RoB publications, we only extracted long-term harms from 15 uncontrolled … measured by transvaginal ultrasound or endometrial biopsy in primarily short-term studies and 3 year-longLong-term followup for efficacy, tolerability, and safety represents a critical gap needed to guide
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/2020-letter-of-appreciation.pdf
    January 01, 2020 - Lo Erin Long Dale Lupu M Pedro Martinez Janet McElhaney Ellen Meara Cody Meissner J.
  3. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2023.pdf
    January 01, 2023 - rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed https://bmjopen.bmj.com/content/13/1/e066872.long … https://bmjopen.bmj.com/content/13/1/e066872.long https://bmjopen.bmj.com/content/13/1/e066872.longLong-term health-related quality of life and symptom severity following hysterectomy, myomectomy, or … Long COVID Models of Care 20. … AHRQ Evidence-based Practice Center and NIH Pathways to Prevention Programs: A Decade-long Partnership
  4. effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_disposition-comments.pdf
    February 29, 2016 - Opioids: insufficient mention of harms related to long-term risks. … (Donelson R, Long A, Spratt K, Fung T. … (Long A, Donelson R, Fung T. Does it matter which exercise? … The long- term harms of opioids are extremely serious. … I very much appreciated the need for long term follow up you highlighted.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
    September 01, 2019 - Efficacy of nebulized fentanyl and low dose ketamine for pain control of patients with long bone fractures … Comparison of intravenous ketamine with morphine in pain relief of long bones fractures: a double blind … Efficacy and safety of morphine and low dose ketamine for pain control of patients with long bone fractures … Effect of intravenous morphine and ketorolac on pain control in long bones fractures. … Expedited delivery of pain medication for long- bone fractures using an intranasal fentanyl clinical
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0075_03-10-2009.pdf
    January 01, 2009 - conjunction with one another, provide the highest rate of disease management with the lowest risk of long-term
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
    May 01, 2015 - Without this information it is difficult to inform parents fully about the long-term implications of … and children with ankyloglossia intended to prevent, mitigate, or remedy attributable medium- and long-term … children with ankyloglossia intended to prevent, mitigate, or remedy attributable other medium- and long-term … Benefits of Treatments To Mitigate Feeding Sequelae Three studies examined medium- and long-term benefits … at this point is a good description of the natural history of ankyloglossia by severity, including long-term
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
    November 27, 2012 - I would say it is impossible to compare drugs over the long-term because if a given drug is not working … For this reason, it is also important to capture long-term safety to obtain a global aspect of how … Long-term safety is not ever going to captured through comparative effectiveness trials, but instead … through long-term registry data (e.g., PSOLAR). … Please state how long remission was maintained Thank you for this comment.
  9. SRDR-Charter-140305 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/data-repository-reviews-charter-140305.pdf
    June 01, 2012 - visibility, recommending technical enhancements to further develop SRDR, and developing a strategy to ensure long … Recommend technical enhancements to improve functionality and usability. − Develop a strategy to ensure long
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
    January 01, 2020 - However, safety concerns emerged from key informant discussions, including unknown long-term harms … Disadvantages of whole-body vibration therapy include unknown long-term safety and out-of-pocket costs … Studies that measured compliance found a wide range, raising questions about long-term adherence for … Nor do we know the potential long-term harms from using whole-body vibration therapy. … RCTs with long followup period.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
    March 01, 2025 - Multiple long-term studies have been conducted that provide insight into the role of digestible carbohydrates … progression and may have underestimated the influence of digestible carbohydrate consumption in the long … A rigorous long-term prospective study in a controlled feeding environment would answer these questions … As studies getting to the outcome of interest are challenging given the long-term nature required, shorter
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
    April 01, 2017 - recurrence with IORT compared with whole breast irradiation; the need for prospective monitoring of long-term … Long-term toxicity of an intraoperative radiotherapy boost using low energy X-rays during breast-conserving … Single-center long-term follow-up after intraoperative radiotherapy as a boost during breast-conserving … Long-term cosmesis and toxicity following 3-dimensional conformal radiation therapy in the delivery of … Predictors of long-term toxicity using three-dimensional conformal external beam radiother- apy to deliver
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
    May 14, 2010 - continued use of pharmacotherapy, and what are the comparative anti-fracture efficacies of continued long-term … Assessment of long-term effects will be based on the consensus definition of “long-term” in studies … Published Online: May 14, 2010 • Other factors (e.g., community dwelling vs. residents of long-term … likelihood of sustaining a fracture during the follow-up period) (c) KQ4: What are the short- and long-term
  14. effectivehealthcare.ahrq.gov/sites/default/files/selection-of-data-sources-chapter-8.pptx
    January 01, 2013 - How long is necessary depends on the research question; in most cases, information about outcomes associated … Data from registries or from clinical care may be ideal for studies requiring long followup. … Data outside the United States It may be easier to obtain complete, long-term data from countries with … This makes it much easier to obtain complete, long-term medical records and to follow individuals in … duration of followup for members in the database, proportion of patients with followup sufficiently long
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
    March 09, 2010 - many unanswered questions about the safety and effectiveness of these drugs, especially for their long-term … • Outcomes for each question KQ1-KQ4 • Primary outcomes: Improvement in intermediate or long-term … The long-term outcomes include pain control, clinical remission, quality of life, growth, development … inflammation, changes in the active joint count, or radiologically evident progression of disease) and/or long-term … • Outcome is change in one of the prespecified intermediate or long-term outcomes and is assessed
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation-future_research.pdf
    January 01, 2013 - followup: Are benefits received from multidisciplinary rehabilitation programs sustained over the long … Followup: Are benefits received from multidisciplinary rehabilitation programs sustained over the long … Question: Are benefits received from multidisciplinary rehabilitation programs sustained over the long … followup: Are benefits received from multidisciplinary rehabilitation programs sustained over the long … The goal of the Executive Plus program is to maximize executive functioning, as well as the long- term
  17. effectivehealthcare.ahrq.gov/sites/default/files/pregnancy_hi_impact.pdf
    January 01, 2012 - The short- and long-term goals of the program are to prevent pregnancy-related complications or maternal … While some experts believe long- term studies are needed to properly evaluate this intervention’s impact … same optimism regarding in utero surgery and its potential to affect patient health outcomes “as long … expert expecting wide acceptance based on parents “wishing to decrease substantive risks of life-long … However, several experts agreed that long-term per-patient costs might be reduced, with one expert
  18. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
    January 01, 2016 - Ultra-long-acting insulin (Tresiba, degludec; Ryzodeg degludec plus aspart) for treatment of type 1 … However, some experts questioned long-term efficacy. … However, some experts questioned the long-term success and cited the need for more data to address … Some cited the lack of long-term efficacy studies as potential barriers for clinicians and patients … Once-weekly exenatide okayed by FDA for T2DM after long look. [internet].
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
    January 01, 2022 - moderate short-term improvements in pain with some cannabis products, but the impact on moderate or long-term … Evidence is too limited to compare effects on serious and long-term harms, even indirectly. … Important limitations include small sample sizes, lack of evidence for moderate and long-term use, and … specific cannabis-based products available in the United 10 States, studies on long-term
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_research-protocol.pdf
    December 23, 2014 - limited to, effects of sedation or imaging dye Timing • Immediate and short-term (≤ 3 months) • Long-term … (> 2 years of age) KQ4 • Immediate and short-term (≤ 3 months) • Long-term (> 3 months) Setting … Moreover given the importance of capturing studies addressing long-term outcomes in older children and … of age with known or suspected infantile hemangiomas • Immediate and short-term (≤ 3 months) or Long-term … 18 years of age with infantile hemangiomas • Immediate and short-term (≤ 2 years of age) • Long-term

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