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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
    September 29, 2014 - Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic … The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain. … - term benefits and harms of long-term opioid therapy. … We agree, which is why the focus is on long-term benefits and harms. … Peer Reviewer 10 General Comments This is a high impact article that is long overdue.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-anticholinergic-medicines_research.pdf
    December 01, 2009 - Conclusions: When used with inhaled corticosteroids and long-acting beta-agonists, tiotropium use was … The reference regimen of inhaled corticosteroids plus long-acting beta- agonists was used by 20.5% of … The adjusted hazard ratio for combination tiotropium plus inhaled corticosteroids plus long- acting … For example, tiotropium plus inhaled corticosteroids plus long-acting beta- agonists was consistently … Importantly our comparison of tiotropium plus inhaled corticosteroids plus long-acting beta-agonists
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-209-evidence-summary-non-pharma-chronic-pain.pdf
    June 01, 2018 - Long-term evidence was sparse. … Intermediate and long-term outcomes were not reported. … term (OR 8.8, 95% CI 2.5 to 30.9) in one trial (SOE: low for short, intermediate and long term) … Evidence was particularly limited on long-term outcomes. … Data on long-term outcomes was particularly limited.
  4. effectivehealthcare.ahrq.gov/products/asthma-pharmacologic-treatment/research-2017
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0416_02-18-2011.pdf
    January 01, 2011 - Document Completion Date: 06-08-11 1 Results of Topic Selection Process & Next Steps  Long-term … Description Nominator: Individual Nomination Summary: The nominator is interested in long-term … Long-term Care of the Frail Elderly Nomination Summary Document http://effectivehealthcare.ahrq.gov … The shift in emphasis from institutional to home and community-based services is a major theme in long-term … In contrast, recent advances in long-term care, such as consumer- directed care and service integration
  6. effectivehealthcare.ahrq.gov/products/chronic-pain-opioid-treatment/research
  7. effectivehealthcare.ahrq.gov/products/chronic-pain-opioid-treatment/research-protocol
  8. effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
    April 01, 2020 - Different long-acting opioids • Four trials (N=2721) of long-acting oxycodone vs. tapentadol reported … • Three trials (N=1405) compared similar doses of long-acting oxycodone vs. … • Three trials (N=957) compared transdermal fentanyl vs. long-acting morphine. … Prescription of long-acting opioids and mortality in patients with chronic noncancer pain. … Rates of adverse events of long-acting opioids in a state medicaid program.
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritized-research-agenda.pdf
    October 01, 2021 - Patient-centered outcomes research (short & long-term) 3. … Patient-centered outcomes research (short & long-term) 3. … Patient-centered outcomes research (short & long-term) 4. … Patient-centered outcomes research (long-term) 3. … Patient-centered outcomes research (long-term) 3.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief2-opioid-withdrawal.pdf
    April 01, 2021 - with pain entitled to Medicare benefits, resulting in an expanded population of patients prescribed long … In patients in whom an individual assessment determines that benefits of long-term opioid therapy do … In patients prescribed long-term opioid therapy for chronic pain, what are the effects of treatments … Effects in subgroups Population Patients prescribed long-term opioid therapy for chronic pain and … Tapering From Long-term Opioid Therapy in Chronic Pain Population.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief2-opioid-withdrawal.pdf
    April 01, 2021 - with pain entitled to Medicare benefits, resulting in an expanded population of patients prescribed long … In patients in whom an individual assessment determines that benefits of long-term opioid therapy do … In patients prescribed long-term opioid therapy for chronic pain, what are the effects of treatments … Effects in subgroups Population Patients prescribed long-term opioid therapy for chronic pain and … Tapering From Long-term Opioid Therapy in Chronic Pain Population.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
    December 19, 2013 - long-acting and dose),dosing strategies, and characteristics of the clinical setting; limitations in … opioid therapy, continued wide variations in practice related to long-term opioid therapy, and the … In patients with chronic pain, what is the effectiveness of long-term opioid therapy versus placebo … opioids • For KQ IIIc: One long-acting opioid vs. another long-acting opioid • For KQ IIId: Short … - plus long-acting opioid vs. long-acting opioid • For KQ IIIe: Scheduled, continuous vs. as-needed
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/insulin-analogues-disposition-081229.pdf
    September 01, 2008 - or long acting? or MDI? it is unclear what the intended comparator is. … Key Questions 1 and 2 Insulin Aspart 70/30 versus Long-acting insulin analogues 1. … Insulin Lispro 75/25 versus Long-acting insulin analogues 1. … Insulin Lispro 50/50 versus Long-acting insulin analogues 1. … "; basal insulin IS long acting and long acting is basal.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
    April 01, 2015 - Thus, we did not use MRI results as a long-term outcome in this review. … What is the evidence for long-term harms? c. … We therefore turned to literature examining benefits for continuing DMT long term. … Long-term events do not differ from short- term events. … PRISMS-4: long-term efficacy of interferon- beta-1a in relapsing MS.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0583-131115.pdf
    March 13, 2013 - mass spectrometric analysis compare with immunoassay analysis for: 1) organ survival, 2) acute and long-term … compared with an induction agent plus a conventional CNI regimen for: 1) organ survival, 2) acute and long-term … conversion) compared with any other CNI minimization strategy for: 1) organ survival, 2) acute and long-term … are recent efforts in kidney transplantation to reduce exposure to CNIs in the hopes of improving long-term … § There is a significant volume of new evidence addressing this topic and long
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    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
    January 01, 2005 - Some patients have frequent, severe symptoms requiring long-term regular use of antireflux medications … who do not need long-term antisecretory medications. … Long-term studies are needed to assess the risks associated with acid suppression on the development … of pneumonia and enteric infections, and to assess the consequences of long-term hypergastrinemia. … The proportion of patients freed from long-term antireflux medications is unclear. Surgical vs.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-b.xlsx
    May 29, 2025 - Exclusion: NR Substance misuse Parent caregiver Short-term facility: 15 Long-term facility: 16 Short-term … Facility: 43 Long-term Facility: 42 51% 82% Parent Caregivers White: 82% Black: 13% Multiracial/prefer … facility: 24 Short-term facility: 37 Long-term facility: 24 A. … (Short-term facility: n=19; Long-term facility: n=12) B. … (Short-term facility: n=18; Long-term facility: n=12) English; Spanish Not explicitly - Parent SMART
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pediatric-cancer-survivorship-protocol.pdf
    June 01, 2020 - Objectives for the Technical Brief Childhood cancer survivors (CCS) face many challenges regarding long-term … GQ3: • Strategies do not need to document alternative care models in detail as long as the difference … Studies may address CCS who recently or long in the past experienced pediatric cancer and are now … Survivors of childhood and adolescent cancer: life-long risks and responsibilities. … term follow up” OR “long-term follow-up”) PubMed [GQ1, Disparities, unselected US long-term studies
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-future_research.pdf
    May 01, 2012 - Needs for Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers, Long-Term … for Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers; Long-Term … for Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers, Long-Term … The definition of “long term” is not clear, but would likely be multiple years. … How do these preferences affect short and long-term patient outcomes*?
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
    February 01, 2012 - Finally, Gap 4 focuses on the specifics of survivorship planning or long-term care planning. … survivorship planning enhance compliance with long-term followup? … Effectiveness of survivorship planning on long-term, comprehensive followup and outcomes. … Does survivorship planning enhance compliance with long-term followup? … The long- term impact of the disease and its treatment should be recognized.

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