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101. Coronary-Artery-Stenting Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
     February 01, 2013 - invasive procedures can also lead to additional invasive tests or treatments that can adversely impact long … three time points: short term (≤30 days after the procedure), medium term (>30 days to 1 year), and long … With respect to the long-term data (>1 year), three RCTs found no significant difference in all-cause … outcomes, and few studies reported long-term outcome data. … Impact of intravascular ultrasound-guided stenting on long-term clinical outcome: a meta-analysis of

102. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
     September 01, 2011 - of these non-biologic DMARDs, methotrexate, whose exact mechanism is unknown, has been used for so long … Therefore, trials require large sample sizes with long followup periods. … Trials that evaluate the efficacy of treatment should be sufficiently long, with frequent assessment … Such studies could also be important for better characterizing long-term outcomes in JIA. … Because JIA is a chronic illness, understanding the long-term adverse effects of these drugs is critical

103. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/14_substanceabuse_potential_high_impact_june_2012.pdf
     January 01, 2012 - Overall High Impact Potential: Long-acting pharmacotherapy for opioid dependence .................. …  Potential for High Impact: Moderately high Long-Acting Pharmacotherapy for Opioid Dependency … Two long-acting versions of currently used pharmacotherapies (buprenorphine and naltrexone) have been … Two novel, long-acting versions of currently used pharmacotherapies (buprenorphine [Probuphine ™ ] … Overall High Impact Potential: Long-acting pharmacotherapy for opioid dependence Overall, experts

104. Future Research Needs for Treatment of Obstructive Sleep Apnea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
     February 01, 2012 - What are long-term outcomes of mandibular advancement device (MAD) treatment? 2. … What are long-term outcomes of mandibular advancement devices (MAD) treatment? 2. … What are long-term outcomes of mandibular advancement devices (MAD) treatment? … since in most cases, treatment can be expected to be life-long. … However, there is potential for large data loss due to long-term followup.

105. Disposition of Comments: CER 228, Nonopioid Pharmacologic Treatments for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-228-nonopioid-pharm-chronic-pain-comments.pdf
     April 16, 2020 - American Psychological Association Question 3 We also appreciate noting the limited evidence on long … "A long-term RCT (N=257) found no differences between duloxetine 40 mg/day versus 60 mg/day in pain … Public Reviewer 15 Celeste Cooper Question 4 RE: Most effects were small; long-term evidence was sparse … As the first report suggests, “…evidence on long-term treatment effectiveness, comparative effectiveness … In addition, and despite the second report’s finding that “…evidence on long- term effectiveness [of

106. The Role of Immunotherapy in the Treatment of Asthma--Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-196-evidence-summary-immunotherapy-asthma.pdf
     March 01, 2018 - Key Messages • Subcutaneous immunotherapy reduces use of long-term control medications. … Sublingual immunotherapy improves asthma symptoms, quality of life and FEV1, and reduces the use of long … Key Points • SCIT reduces the need for long-term control medication (moderate strength of evidence [ … • SLIT improves disease-specific quality of life and decreases use of long-term control medications … SLIT improves asthma symptoms, reduces long-term control medication use, improves disease- specific

107. EHC Protocol: Updating the Measurement Criteria for AHRQ's National Healthcare Quality and Disparities Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/updating-criteria-qdr-protocol.pdf
     September 06, 2023 - , the possibility of unforeseen adverse effects on vulnerable populations, and how best to achieve long-term … order-on-further-advancing-racial-equity-and-support-for-underserved-communities- through-the-federal- government/#:~:text=On%20my%20first%20day%20in,long … executive-order-on-further-advancing-racial-equity-and-support-for-underserved-communities-through-the-federal-government/#:%7E:text=On%20my%20first%20day%20in,long … executive-order-on-further-advancing-racial-equity-and-support-for-underserved-communities-through-the-federal-government/#:%7E:text=On%20my%20first%20day%20in,long … executive-order-on-further-advancing-racial-equity-and-support-for-underserved-communities-through-the-federal-government/#:%7E:text=On%20my%20first%20day%20in,long

108. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
     August 10, 2010 - Title: Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-risk Preschoolers; Long … neurodevelopmental stage when children consolidate social, emotional and cognitive skills that affect long … Long-term effects Since ADHD is a chronic disorder, many children, teens and adults stay on medications … ADHD in preschoolers and long-term effects of ADHD pharmacotherapy Alternate text to accompany figure … Studies will be limited for key question two to any publication from 1997 to 2010 because long-term

109. Attention Deficit Hyperactivity Disorder: Diagnosis and Treatment in Children and Adolescents - Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
     November 01, 2021 - effectiveness of standard and novel interventions for ADHD, and their potential long-term adverse … Searches will go back to 1980, when long acting stimulants were introduced, heralding the modern era … Is There Long-Term Benefit From Stimulant Treatment for ADHD? … Long-Term Effects of Stimulant Treatment for ADHD: What Can We Tell Our Patients? … Debate: Are Stimulant Medications for Attention-Deficit/Hyperactivity Disorder Effective in the Long

110. Treatment Strategies for Women With Coronary Artery Disease: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
     February 01, 2013 - fibrinolysis/supportive therapy on intermediate- or long-term clinical outcomes (nonfatal MI, death, … 5 What is the effectiveness of the following treatment strategies on short-, intermediate- or long- … fibrinolysis/supportive therapy on intermediate- or long-term clinical outcomes (nonfatal MI, death, … Recommended study design: (preferable) large long-term clinical trial with women- only enrollment or … With the CABG strategy: Low (women and men) for long-term (4- to 5-year) composite outcomes 3.

111. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/14_substance_abuse_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - Overall high-impact potential: long-acting pharmacotherapy for opioid dependence .................. …  Potential for High Impact: Moderately high Long-Acting Pharmacotherapy for Opioid Dependency … Long-acting formulations of these pharmacotherapies might address these issues. … A novel, long-acting version of currently used pharmacotherapy (buprenorphine [Probuphine ™ ]) has … Overall high-impact potential: long-acting pharmacotherapy for opioid dependence Overall, experts

112. Topic 0589 Cleaning and Monitoring of HAIs NSD SJ Clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0718-140819.pdf
     March 11, 2013 - Staff-Generated PICO Primary outcome: HAI rates in patients Population(s): Patients in hospitals or long … Intervention(s): Cleaning, disinfecting, and environmental monitoring of surfaces in hospital or long … Population(s): Surfaces in hospital or long term care settings, outpatient settings, free standing surgical

113. Executive Summary - Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
     January 01, 2023 - versus placebo,2 and two new observational studies, one of plant-based comparable THC to CBD versus long-acting … new observational study (n=1,310) compared an extracted comparable THC to CBD ratio product versus long-acting … small short-term improvements in pain with some cannabis products, but the impact on moderate or long … ), studies evaluating specific cannabis-based products available in the United States, studies on long-term … Effectiveness, Safety, and Tolerability of Nabiximols Oromucosal Spray vs Typical Oral Long-Acting

114. Screening and Diagnosing Gestational Diabetes Mellitus Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_disposition-comments.pdf
     January 01, 2020 - Long-term risks are not directly related to short term outcomes. … We agree that there should be a distinction between short-term and long-term outcomes. … We have reported on long-term outcomes among the offspring although the evidence was very limited. … The studies that met the inclusion criteria did not report on long-term resource use. … Long-term Outcomes in Mothers Diagnosed With Gestational Diabetes Mellitus and Their Offspring.

115. Weight-Loss-Surgery Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_executive.pdf
     June 01, 2013 - The evidence for both short- and long-term outcomes was assessed. … Long-Term Outcomes There are few long-term data on patients with diabetes or IGT in this weight class … Thus, strength of evidence for long-term adverse events is rated insufficient. … Thus, we have almost no data on long-term efficacy and safety. … Again, we found almost no long-term adverse events data for our target population.

116. Systematic Review of Intermittent Inhaled Corticosteroids and of Long-acting Muscarinic Antagonists for Asthma | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/asthma-pharmacologic-treatment/research-protocol

117. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
     February 01, 2012 - Do FGAs and SGAs differ in other short- and long- term outcomes when used in children, youth, and young … Short-term is defined as outcomes occurring within 6 months; long-term is defined as outcomes occurring … Key Question 3: Short- and long-term outcomes. … Summary of the strength of evidence for other short- and long-term outcomes (Key Question 3) Outcome … In particular, the median study duration of 8 weeks is insufficient to assess some long-term efficacy

118. Alcohol-Misuse-Drug-Therapy Consumer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_consumer.pdf
     February 01, 2016 - It can be a long-term or lifelong condition and could come back after treatment. … Alcohol use disorder can be a long-term condition, like high blood pressure or asthma. … You may need treatment over a long period of time. … � How long will I need to take the medicine before I know if it is helping? … � If the medicine helps, how long will I need to keep taking it?

119. Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix F2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-apf2_0.xlsx
     January 01, 2018 - NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR Dougados, 1999 Fair AS NSAID Meloxicam 15 mg/d 52 Long … NR NR NR NR NR NR NR NR NR NR NR NR NR NR Dahlberg, 2009 Fair OA (hip/knee) Celecoxib 200 mg/d 52 Long … NR NR NR NR NR NR NR NR NR NR NR NR NR NR Dahlberg, 2009 Fair OA (hip/knee) Diclofenac 100 mg/d 52 Long … NR NR NR NR NR NR NR NR NR NR Nissen, 2016 Fair Mixed Celecoxib 200 to 400 mg/d (mean 209 mg/d) 80 Long … NR NR NR NR NR NR NR NR NR Nissen, 2016 Fair Mixed Ibuprofen 1800 to 2400 mg/d (mean 2045 mg/d) 80 Long

120. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-nursing-home-characteristics_research-protocol.pdf
     November 03, 2011 - Review Protocol Project Title: Comparison of Characteristics of Nursing Homes and Other Residential Long-Term … In 2001, the Institute of Medicine Committee on Improving the Quality of Long-Term Care specifically … Long-term care for older adults. The role of the family. … Improving the quality of long-term care. Washington, DC: National Academy Press; 2001. 27. … Office of Disability, Aging, and Long-Term Care Policy.