-
effectivehealthcare.ahrq.gov/products/thromboembolism-update/research-2017
June 22, 2017 - Initiated Feb. 17, 2016 Research Protocol Jun. 22, 2017 Systematic Review Venous Thromboembolism Prophylaxis … Most studies evaluated low molecular weight heparin (LMWH), not low-risk interventions (such as aspirin … For THR: low molecular weight heparin (LMWH) has lower risk than unfractionated heparin (UFH) of various … Conclusions
VTE prophylaxis after major orthopedic surgery trades off lowered VTE risk with possible … Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update.
-
effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - Most studies evaluated low molecular
weight heparin (LMWH), not low-
risk interventions (such as aspirin … agents within the
defined classes of antiplatelet agents, low molecular
weight heparin (LMWH), unfractionated … = low molecular
weight heparin, OR = odds ratio, RCT = randomized controlled trials, VKA = vitamin … = low molecular weight
heparin, OR = odds ratio, PE = pulmonary embolism, RCT = randomized controlled … = low molecular weight
heparin, OR = odds ratio, RCT = randomized controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - Most studies evaluated low molecular
weight heparin (LMWH), not low-
risk interventions (such as aspirin … agents within the
defined classes of antiplatelet agents, low molecular
weight heparin (LMWH), unfractionated … = low molecular
weight heparin, OR = odds ratio, RCT = randomized controlled trials, VKA = vitamin … = low molecular weight
heparin, OR = odds ratio, PE = pulmonary embolism, RCT = randomized controlled … = low molecular weight
heparin, OR = odds ratio, RCT = randomized controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
March 01, 2012 - Finally, when LMWH agents were compared
versus mechanical prophylaxis, the only significant
difference … The balance of benefits and harms from using enoxaparin
versus another low molecular weight heparin … = low molecular weight heparin;
M = moderate; NNH = number needed to harm; NNT = number needed to … information for an additional between
class comparison (oral direct factor Xa inhibitor versus
injectable low … molecular weight heparin) in KQ 5.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
June 22, 2017 - site bleeding risk [6], pharma has never
selected aspirin as an active comparator
in RCTs studying low … molecular weight
heparin (LMWH), antithrombin
IIImediated selective factor Xa inhibitors
(ATIII), … versus no
VTE prophylaxis did not provide strong
evidence that mechanical prophylaxis
reduced the … Therefore similar rates
of VTE between aspirin and LMWH
arms may indicate that LMWH is more
effective … A total of 1803 patients in
this study were prospectively randomized
to LMWH or LMWH and IPC.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_surveillance.pdf
December 01, 2012 - weight heparin OR low molecular weight heparin OR lmwh OR enoxaparin OR dalteparin OR
nadroparin OR … weight heparin OR low molecular weight heparin OR lmwh OR enoxaparin OR dalteparin OR
nadroparin OR … weight heparin OR low molecular weight heparin OR lmwh OR enoxaparin OR dalteparin
OR nadroparin OR … weight heparin OR low molecular weight heparin OR lmwh OR enoxaparin OR
dalteparin OR nadroparin OR … weight heparin OR low molecular weight heparin OR lmwh OR enoxaparin OR
dalteparin OR nadroparin OR
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
February 01, 2008 - than one method of throboprophylaxis
being compared with another method of thromboprophylaxis (i.e. low-molecular … weight
heparin versus low-molecular weight heparin plus compression stockings versus
compression stockings … Low molecular weight heparin
PE Pulmonary embolism
PIOPED Prospective Investigation of Pulmonary … weight heparin OR low molecular
weight heparin OR lmwh OR enoxaparin OR dalteparin OR nadroparin OR … molecular weight heparin
LMWH
Pulmonary embolism
PE
PIOPED
Randomized controlled trial
RCT
Relative
-
effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
February 01, 2008 - than one method of throboprophylaxis
being compared with another method of thromboprophylaxis (i.e. low-molecular … weight
heparin versus low-molecular weight heparin plus compression stockings versus
compression stockings … Low molecular weight heparin
PE Pulmonary embolism
PIOPED Prospective Investigation of Pulmonary … weight heparin OR low molecular
weight heparin OR lmwh OR enoxaparin OR dalteparin OR nadroparin OR … molecular weight heparin
LMWH
Pulmonary embolism
PE
PIOPED
Randomized controlled trial
RCT
Relative
-
effectivehealthcare.ahrq.gov/products/blood-clots-hip-knee-surgery/research-protocol
August 06, 2010 - than one method of throboprophylaxis being compared with another method of thromboprophylaxis (i.e. low-molecular … weight heparin versus low-molecular weight heparin plus compression stockings versus compression stockings … Low molecular weight heparin
PE
Pulmonary embolism
PIOPED
RCT
Randomized controlled … anticoagulants OR aspirin OR clopidogrel OR ticlopidine OR prasugrel OR heparin OR heparinoids OR ufh OR low-molecular … weight heparin OR low molecular weight heparin OR lmwh OR enoxaparin OR dalteparin OR nadroparin OR
-
effectivehealthcare.ahrq.gov/products/vte-prophyalaxis/research-protocol
January 12, 2012 - The pharmacologic agents include unfractionated heparin (UFH) and low-molecular-weight heparin (LMWH; … Nearly 60 percent of bariatric surgeons preferred LMWH for prophylaxis, but many were uncertain about … = low-molecular-weight heparin; PE = pulmonary embolism; SCD = sequential circumferential compression … Low-molecular-weight heparin in patients with renal insufficiency. … Definition of Terms
DVT = deep vein thrombosis,
LMWH = low-molecular-weight heparin
PE = pulmonary
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
March 01, 2011 - The pharmacologic agents include unfractionated heparin (UFH) and low-molecular-weight
heparin (LMWH … = low-molecular-weight heparin; PE = pulmonary embolism; SCD = sequential
circumferential compression … (KQs 1–8)
Interventions (KQs 1–8)
Unfractionated heparin
Low-molecular-weight … Low-molecular-weight heparin in patients with renal insufficiency. … Definition of Terms
DVT = deep vein thrombosis,
LMWH = low-molecular-weight heparin
PE = pulmonary
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
February 17, 2016 - molecular weight heparin, factor Xa inhibitors, direct thrombin inhibitors, and
mechanical devices … molecular weight heparin,
factor Xa inhibitors, direct thrombin inhibitors, and mechanical devices) … molecular weight heparin All KQ
o Injectable unfractionated heparin KQ 1, 4 (in combination), 5, … molecular weight heparin, factor Xa inhibitors) and 2) comparisons of individual
interventions. … clopidogrel or ticlopidine or
prasugrel or "Heparin"[Mesh] or "Heparinoids"[Mesh] or heparin or UFH or LMWH
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
March 01, 2012 - Use of
LMWH (compared with aspirin and mechanical device)
? … molecular weight heparin for the prevention of
deep venous thrombosis following total hip
replacement … Dosages for certain LMWH should be examined.
b. … Reduction of out-of-hospital
symptomatic venous thromboembolism by extended
thromboprophylaxis with low-molecular-weight … heparin
following elective hip arthroplasty: a systematic review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
May 01, 2013 - We included
studies of unfractionated heparin (UFH) and low molecular
weight heparins (LMWH) delivered … initiation)
• Traumatic brian injury (KQ 2b)
Interventions (KQs 1-8)
• Unfractionated heparin
• Low-molecular-weight … heparin
• Factor Xa inhibitors
• Direct thrombin inhibitor
• Mechanical devices
• IVC filters … = low-molecular-weight heparin; PE = pulmonary embolism; PTT = partial thromboplastin time; SCD = sequential … Comparison of
two low-molecular-weight heparin dosing regimens for patients
undergoing laparoscopic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_disposition-comments.pdf
May 29, 2013 - Perhaps consider including a brief review of the mechanism of
action of unfractionated heparin and low … molecular weight heparin
We have added additonal text regarding
the mechanism of action of these … The authors also recently conducted a study of
the comparative effectiveness of unfractionated and low … molecular weight heparin for
the prevention of VTE in bariatric surgery which is in press at Archives … in these patients (various higher doses of LMWH, LMWH vs SCD vs
combination, duration of prophylaxis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-high-risk-drugs-rapid-response.pdf
January 01, 2024 - molecular–weight heparin (LMWH) may undergo
anti-Xa monitoring as part of their anticoagulation management … weight heparin. … weight heparin (LMWH, with variable dosing based on provider monitoring of
LMWH via anti-Xa assay … Low-molecular-weight heparin and
mortality in acutely ill medical patients. … The effect of
anti-Xa monitoring on the safety and efficacy
of low-molecular-weight heparin
anticoagulation