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61. Screening for Hepatitis C Virus Infection in Adolescents and Adults: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/WEqCV3NvnZAeLdC_pp6nVK
    October 01, 2018 - Outcomes were mortality, morbidity (eg, cirrhosis, hepatic decompensation, liver transplant, extrahepatic … American Association for the Study of Liver Diseases, Infectious Diseases Society of America. … Excess liver-related morbidity of chronic hepatitis C patients, who achieve a sustained viral response … Kasahara A, Hayashi N, Mochizuki K, et al; Osaka Liver Disease Study Group. … Liver Int. 2008;28(10):1363-1369. doi:10.1111/j.1478-3231.2008.01860.x 89.

62. Screening for Lipid Disorders in Children and Adolescents: US Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/vmHooQ6ABG9CagdUXv2_rx
    August 25, 2021 - Abnormal liver and musculoskeletal laboratory values were reported with statin use; however, most trials … Further, the clinical importance of transient eleva- tions in liver enzyme or creatine kinase levels … is unknown.1,17 In the statin trials discussed above, elevated liver enzyme lev- els of 3 times or more … In the 10-year observational follow-up of this trial, el- evated liver enzyme levels at this threshold

63. Draft Research Plan: Healthy Diet, Physical Activity, and/or Weight Loss to Prevent Cardiovascular Disease in Adults: Behavioral Counseling Interventions | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/behavioral-counseling-interventions-promote-healthy-diet-physical-activity-weight-loss-prevent-cardiovascular-disease-adults
    May 18, 2023 - osteoarthritis, cardiovascular disease, diabetes mellitus, polycystic ovary syndrome, nonalcoholic fatty liver

64. Screening and Behavioral Counseling Interventions to Reduce Unhealthy Alcohol Use in Adolescents and Adults: USPSTF Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/RwHjq3L5fN5gdWsp_sSwA3
    August 02, 2018 - acute conditions (eg, injuries from motor vehicle collisions) and chronic conditions (eg, alcoholic liver … acute conditions (eg, injuries from mo- tor vehicle collisions) and chronic conditions (eg, alcoholic liver … pattern of drinking that is already causing damage to health; the damage may be either physical (eg, liver … years of potential life lost.6 Of these 88 000 deaths, 44% were from chronic conditions (eg, alcoholic liver … affects development of the fetal brain, endocrine sys- tem, gastrointestinal tract, heart, kidney, and liver

65. Evidence Summary: Nonpregnant Adolescents and Adults: Human Immunodeficiency Virus (HIV) Infection: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-nonpregnant-adolescents-and-adults1/human-immunodeficiency-virus-hiv-infection-screening
    June 11, 2019 - significant differences between early vs delayed initiation of ART and risk of other harms, such as liver … D:A:D study (n = 45,544) found long-term tenofovir use associated with increased risk of end-stage liver … Use of antiretroviral therapy and risk of end-stage liver disease and hepatocellular carcinoma in HIV-positive … Antiretroviral drug-related liver mortality among HIV-positive persons in the absence of hepatitis B … Hepatic harms: an observational study found tenofovir associated with increased risk of end-stage liver

66. Final Research Plan: Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/vitamin-d-calcium-or-combined-supplementation-for-the-primary-prevention-of-fractures-in-adults-preventive-medication
    June 23, 2016 - disorders, malabsorptive disorders, celiac disease, cystic fibrosis, short gut syndrome, cholestatic liver

67. Recommendation: Unhealthy Alcohol Use in Adolescents and Adults: Screening and Behavioral Counseling Interventions | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/unhealthy-alcohol-use-in-adolescents-and-adults-screening-and-behavioral-counseling-interventions
    November 13, 2018 - acute conditions (eg, injuries from motor vehicle collisions) and chronic conditions (eg, alcoholic liver … of potential life lost. 6 Of these 88,000 deaths, 44% were from chronic conditions (eg, alcoholic liver … affects development of the fetal brain, endocrine system, gastrointestinal tract, heart, kidney, and liver … pattern of drinking that is already causing damage to health; the damage may be either physical (e.g., liver … Persisting with substance use despite clear evidence of overtly harmful consequences, such as harm to the liver

68. Screening for HIV Infection in Asymptomatic, Nonpregnant Adolescents and Adults: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/q_zxLD9JZFGoSPCrEHNk2g
    June 11, 2019 - significant differences between early vs delayed initiation of ART and risk of other harms, such as liver … D:A:D study (n = 45 544) found long- term tenofovir use associated with increased risk of end-stage liver … Hepatic harms: an observational study found tenofovir associated with increased risk of end-stage liver … Use of antiretroviral therapy and risk of end-stage liver disease and hepatocellular carcinoma in HIV-positive … Antiretroviral drug-related liver mortality among HIV-positive persons in the absence of hepatitis B

69. Screening for Syphilis Infection During Pregnancy: USPSTF Reaffirmation Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/YJtsbuhNtrLyn6NpJZtfXk
    April 24, 2023 - neonatal death, and significant abnormalities in the infant such as deformed bones, anemia, enlarged liver … neonatal death, and sig- nificant abnormalities in the infant such as deformed bones, ane- mia, enlarged liver … neonatal death, and significant abnormalities in the infant such as deformed bones, anemia, enlarged liver

70. Evidence Summary: Hepatitis B Virus Infection in Pregnant Women: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/hepatitis-b-virus-infection-in-pregnant-women-screening
    July 23, 2019 - infants infected with HBV, often resulting in serious long-term health complications such as cirrhosis, liver

71. Archived: Final Research Plan: Aspirin to Prevent Cancer: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    October 07, 2013 - conditions that may be affected by aspirin use in terms of benefits or harms are proposed: diabetes, liver

72. Ad-Br2Otj67Fendhhkltpa (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/aD-Br2oTJ67FeNdHHkLtPA
    damage in babies of pregnant women Stroke, permanent brain injury, muscle and nerve damage Liver … violent behaviour Psychosis after repeated use of high doses Permanent damage to brain cells Liver … difficulties, slowed reactions, hypoxia Delirium, seizures, coma, organ damage (heart, lungs, liver

73. Draft Recommendation: Unhealthy Alcohol Use in Adolescents and Adults: Screening and Behavioral Counseling Interventions | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/unhealthy-alcohol-use-adolescents-adults-behavioral-counseling-interventions
    August 05, 2025 - alcohol-related deaths are due to the health effects of chronic excessive use (e.g. heart disease, cancer and liver … between excessive alcohol consumption and a range of adverse health outcomes including hypertension, liver

74. Archived: Final Research Plan: Latent Tuberculosis Infection: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan105/latent-tuberculosis-infection-screening-september-2016
    September 25, 2014 - Because of reports of severe liver injury and death, the CDC recommends that rifapentine and pyrazinamide

75. Recommendation: Human Immunodeficiency Virus (HIV) Infection: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/human-immunodeficiency-virus-hiv-infection-screening
    June 11, 2019 - fosamprenavir (relative rate, 1.47 [95% CI, 1.01-2.15]) were associated with increased risk of end-stage liver … these outcomes (relative rate, 0.51 [95% CI, 0.32-0.83]). 49 However, the absolute risk of ART-related liver … Use of antiretroviral therapy and risk of end-stage liver disease and hepatocellular carcinoma in HIV-positive … Antiretroviral drug-related liver mortality among HIV-positive persons in the absence of hepatitis B

76. Screening for Hepatitis B Infection in Pregnant Women: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/pFEM-gRfk6-Qj7grXkZQzC
    February 11, 2019 - infected with HBV, often resulting in seri- ous long-term health compli- cations such as cirrhosis, liver

77. Final Research Plan: Osteoporosis to Prevent Fractures: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening
    November 18, 2021 - syndrome, celiac disease, inflammatory bowel disease, history of gastric bypass surgery, anorexia, chronic liver

78. Archived: Final Evidence Summary: Obesity in Adults: Screening and Management | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary38/obesity-in-adults-screening-and-management-2012
    October 15, 2011 - We did not find studies associating orlistat with liver, kidney, or pancreas damage, other than case … prescription) and 60 mg (over-the-counter), to include “new safety information about cases of severe liver … Questions and answers: orlistat and severe liver injury. FDA Drug Bulletin. May 26, 2010. … injury 0, 1 (event monitoring cohort) - - UK monitoring study reported elevated liver test results … adverse reactions FDA recently added warning to label to orlistat about possible risk for severe liver

79. Effectiveness of Primary Care–Relevant Treatments for Obesity in Adults: A Systematic Evidence Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/hbSopN6uA9u-4EQuKtRGDP
    October 01, 2011 - 5 studies found that orlistat recipients required more vitamin supplementation during the study – Liver … injury 0, 1 (event monitoring cohort) – – UK monitoring study reported elevated liver test results … We did not find studies associating orlistat with liver, kidney, or pancreas damage, other than case … prescription) and 60 mg (over-the-counter), to include “new safety information about cases of severe liver … Questions and answers: orlistat and severe liver injury. FDA Drug Bulletin. May 26, 2010.

80. Screening for HIV Infection: US Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/efwy72cuMdhcF2jotkhTzC
    March 29, 2019 - prenavir (relative rate, 1.47 [95% CI, 1.01-2.15]) were associated with increased risk of end-stage liver … these outcomes (relative rate, 0.51 [95% CI, 0.32-0.83]).49 However, the absolute risk of ART-related liver … Use of antiretroviral therapy and risk of end-stage liver disease and hepatocellular carcinoma in HIV-positive … Antiretroviral drug-related liver mortality among HIV-positive persons in the absence of hepatitis B