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1. Liver-Cancer Executive (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
   October 01, 2014 - Studies that used explanted livers as the reference standard reported lower sensitivity than studies … studies that compared the accuracy of transplant decisions based on CT against primarily explanted livers … underwent transplantation based on Milan criteria had no HCC lesions on examination of explanted livers … Liver Cancer. www.cancer.gov/ cancertopics/types/liver. Accessed September 21, 2011. 26 3. … New OPTN/UNOS policy for liver transplant allocation: standardization of liver imaging, diagnosis,

2. Liver-Cancer Research-Protocol (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
   July 24, 2013 - Alternative tracers have been investigated for liver cancer. … the explanted liver … explanted liver … Liver Cancer. http://www.cancer.gov/cancertopics/types/liver. Accessed September 21, 2011. 3. … liver.

3. Liver-Cancer-Therapy Executive (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_executive.pdf
   May 01, 2013 - unresectable primary hepatocellular carcinoma (HCC) who are not candidates for surgical resection or liver … Condition Hepatocellular carcinoma is the most common primary liver tumor. … to assess the prognosis of patients with underlying liver disease. … Liver transplant considerations for evaluation, CTP, and MELD. … Liver Int. 2010 May;30(5):741-9. PMID: 20331507. 34. Yan S, Xu D, Sun B.

4. Liver Diseases | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/liver-diseases

5. Liver Cancer | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/liver-cancer

6. Liver Transplantation | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/liver-transplantation

7. Liver-Cancer-Therapy Research-Protocol (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
   November 28, 2012 - the prognosis of patients with underlying liver disease. … Another scoring system for chronic liver disease is the Model for End-Stage Liver Disease (MELD) score … Liver transplant considerations for evaluation, CTP, and MELD. … Pathologic response and microdosimetry of 90Y microspheres in man: review of four explanted whole livers … Liver International 2004;24(6):625-9. PMID: 15566514 25.

8. Fatty Liver Disease | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/fatty-liver-disease

9. Liver Function Tests | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/liver-function-tests

10. Colorectal-Cancer-Liver-Metastases-Therapies Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_executive.pdf
    December 01, 2012 - Patients with unresectable, liver-dominant metastases (i.e., majority of disease located in the liver … metastases or liver-dominant metastases. … The scope of the review was liver-directed therapy versus liver- directed therapy. … Pathologic response and microdosimetry of 90Y microspheres in man: Review of four explanted whole livers … Radiation therapy for liver cancer. 2012. www.cancer.org/Cancer/LiverCancer/DetailedGuide/liver-cancer

11. Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/liver-cancer/research

12. Imaging Techniques for the Surveillance, Diagnosis, and Staging of Hepatocellular Carcinoma | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/liver-cancer/research-protocol

13. Local Therapies for Unresectable Primary Hepatocellular Carcinoma | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/liver-cancer-therapy/research

14. Local Therapies for Unresectable Primary Hepatocellular Carcinoma: Comparative Effectiveness Review | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/liver-cancer-therapy/research-protocol

15. Disposition of Comments Report for Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
    December 11, 2012 - Disposition of Comments Report for Local Hepatic Therapies for Metastases to the Liver From Unresectable … Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer. … Was the comparative effectiveness being evaluated among different liver- directed therapies, or of liver … The scope of the review was liver-directed therapy versus liver-directed therapy. … No high-quality RCT’s exist for liver-directed therapies for colorectal liver mets.

16. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
    September 27, 2012 - therapy, patients should have liver-only metastases or liver-dominant metastases. … Liver-directed therapy is an option for many of these patients whose liver metastases are unresectable … to the liver and have no evidence of extrahepatic disease? … patients with initially unresectable liver metastases from CRC who receive liver- directed therapy(ies … Pathologic response and microdosimetry of 90Y microspheres in man: review of four explanted whole livers

17. Local Therapies for Unresectable Colorectal Cancer Metastases to the Liver: A Comparative Effectiveness Review | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/colorectal-cancer-liver-metastases-therapies/research-protocol

18. Hepatic-Fibrosis White-Paper (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatic-fibrosis_white-paper.pdf
    April 01, 2014 - The gold standard for diagnosing liver fibrosis and cirrhosis is a liver biopsy. … Discordance between biochemical markers of liver activity and fibrosis (Actitest- Fibrotest) and liver … Enhanced Liver Fibrosis (ELF) test accurately identifies liver fibrosis in patients with chronic … Discordance between biochemical markers of liver activity and fibrosis (Actitest- Fibrotest) and liver … Enhanced Liver Fibrosis (ELF) test accurately identifies liver fibrosis in patients with chronic

19. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0399_01-07-2011.pdf
    January 01, 2011 - local therapies 1) for the treatment of unresectable HCC 2) in the setting of HCC as a bridge to liver … transplant or to downstage tumor prior to liver transplantation, and 3) for the treatment of unresectable … Staff-Generated PICO: Comparative effectiveness of the various liver-directed therapies for unresectable … Staff-Generated PICO: Comparative effectiveness of the various liver-directed Local Therapies for the … For metastatic liver disease, local therapy may be used in an attempt to prolong survival and/or to

20. Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/colorectal-cancer-liver-metastases-therapies/research