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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/autism-spectrum-disorder-in-young-children-screening
February 16, 2016 - after a positive screening result, particularly if confirmatory testing is delayed because of resource limitations … In addition to the limitations of the evidence in size, study design, and other sources of heterogeneity … This is of particular concern when there is a delay in confirmatory testing because of resource limitations
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/TkWNoq6KQb3SoZ54gscLCQ
July 25, 2016 - -
lence of cirrhosis at baseline), intermediate and clinical outcomes
evaluated, and methodological limitations … for chronic HBV infection in
2016 and may have fewer kidney and bone toxicities compared
with TDF.85
Limitations … This review has several limitations. … Evidence
Studies observations (No.);
study designs Summary of findings
Consistency
and precision Other limitations … patient populations, the intermediate and
clinical outcomes evaluated, and presence of methodological
limitations
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-section-4-evidence-review-development
June 22, 2025 - "Poor" studies have at least one "fatal flaw" or multiple important limitations. … Overall study quality (combined summary of individual study-level quality assessments)
Body of evidence limitations … (qualitative descriptions of important limitations in body of evidence from what would have been desired
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/ovarian-cancer-screening
February 13, 2018 - Fair-quality studies were assessed as not meeting all of the quality criteria but did not have critical limitations … low, or insufficient based on established methods 19 and addressed the consistency, precision, and limitations … This review has limitations related to the types of evidence considered. … Randomized trial evidence can have limitations in terms of generalizability and applicability to usual … Test
No. of Studies
(No. of Participants)
Summary of Findings
Consistency and Precision
Limitations
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/vitamin-d-calcium-or-combined-supplementation-for-the-primary-prevention-of-fractures-in-adults-preventive-medication
April 17, 2018 - Abstract
Introduction
Methods
Results
Discussion
Limitations … for Effectiveness and Comparative Effectiveness Reviews , 13 which specifies the assessment of study limitations … eligible for the review of harms, but all were excluded for poor quality because of many methodologic limitations … This review and the body of evidence included in this review has several limitations. … Analyzed)
Summary of Findings
Consistency
and Precision
Reporting Bias
Body of Evidence Limitations
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/DPq7_eawq-Ts6XLowaTaNA
November 27, 2018 - Studies
(No. of
Observations) Summary of Findings by Outcome
Consistency and
Precision
Body of Evidence Limitations … Studies
(No. of
Observations) Summary of Findings by Outcome
Consistency and
Precision
Body of Evidence Limitations … Studies
(No. of
Observations) Summary of Findings by Outcome
Consistency and
Precision
Body of Evidence Limitations … Limitations
This study had several limitations. … Fourth, there are limitations in the evidence that relate primar-
ily to the considerable diversity of
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-nonpregnant-adults-and-adolescents-june-2016
June 07, 2016 - developed by the USPSTF. 13 Statistical meta-analysis was not performed because of methodological limitations … Methodologic limitations for both studies include minimal demographic information and unclear descriptions … Limitations of studies include lack of demographic information for tested individuals and reduced applicability … Limitations of this systematic review include using only English-language articles, which could result … Key Question
Main Findings From Previous USPSTF Reviews
Studies Identified for Update
Limitations
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
September 28, 2021 - Intervention studies rated as poor quality had several important limitations, including at least 1 of … likelihood models (REMLs) with Knapp-Hartung correction. 20 , 21 This analytic approach overcomes limitations … publication, selective outcome reporting, or selective analysis reporting), and study quality (ie, study limitations … 93 Reviews comparing the test performance attributes of available risk assessment models have found limitations … Limitations
The evidence review has several limitations.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/zk8YxjaQxLGUTtt__nBQB_
September 09, 2021 - Studies rated as “poor” qual-
ity due to critical methodological limitations were excluded. … overall quality
of the studies, consistency of results between studies, precision of
findings, and limitations … This review had several limitations. … Fourth, there are also limitations to understanding of the di-
rect impact of screening relative to other … Considering the methodological limitations in the
evidence base of antidepressants for depression:
a
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/bQNXFv9Q5uaAQvWH6B7VWV
June 11, 2019 - Summary of Findings by Outcome
Consistency/Precision;
Reporting Bias
Overall
Quality
Body of Evidence
Limitations … CI, 0.59-1.11); I2 = 0% Consistent; imprecise
No reporting bias detected
Good See Body of Evidence
Limitations … be explained by
level of adherence); precise
No reporting bias detected
Good See Body of Evidence
Limitations … Summary of Findings by Outcome
Consistency/Precision;
Reporting Bias
Overall
Quality
Body of Evidence
Limitations … Limitations
This review had some limitations.
-
www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/perinatal-depression-interventions-to-prevent
February 23, 2023 - Share to Facebook
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Print
in progress
Draft Research Plan
Perinatal Depression: Preventive Interventions
February 23, 2023
Recommendations made by the USPSTF are independent of the U.S. government. T…
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/kGvn_HBPEEdfu2rs38VN8_
March 11, 2025 - Evidence on the effectiveness of interventions to improve
food security was hampered by methodologic limitations … Setting aside these limitations, the evidence on inter-
ventions to reduce food insecurity was generally … Insecurity
Study design (No. of observations) Summary of findings Consistency and precision Other limitations … Limitations
There were several limitations related to the scope and methods of
this review. … In addition, there are critical limitations of the evidence.
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
August 20, 2024 - Methodologic limitations included unclear documentation of iron deficiency or use of supplementation … association between a change in maternal iron status and clinical outcomes, due to serious methodological limitations … Limitations
This review had several limitations. … participants)
Summary of findings by outcome
Consistency/precision, reporting bias
Body of evidence limitations … participants)
Summary of findings by outcome
Consistency/precision, reporting bias
Body of evidence limitations
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/CXDusYW7s2xdypXMpnW9sw
June 20, 2023 - Studies rated as “poor” qual-
ity due to critical methodological limitations were excluded, to limit … overall quality of the
studies, consistency of results between studies, precision of findings,
and limitations … Anxiety Screening
No. of studies
(No. randomized) Summary of findings
Consistency
and precision Other limitations … Limitations
This review had several limitations.
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/perinatal-depression-interventions-to-prevent
June 01, 2023 - Share to Facebook
Share to X
Share to WhatsApp
Share to Email
Print
in progress
Final Research Plan
Perinatal Depression: Preventive Interventions
June 01, 2023
Recommendations made by the USPSTF are independent of the U.S. government. T…
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/GcjfCZtGpACQMv2KScLbEu
June 11, 2019 - based on quality of studies, consistency of
results between studies, precision of estimates, study limitations … dine monotherapy in risk of early infant death (4.4% vs 3.2%,
P = .43) or stillbirth.9 Methodological limitations … Findings by Outcome
Consistency
and Precision;
Reporting Bias
Overall Risk
of Bias/Quality Other Limitations … Findings by Outcome
Consistency
and Precision;
Reporting Bias
Overall Risk
of Bias/Quality Other Limitations … Limitations
This review had several limitations.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/HQGXw2wkcM7q6TA5eWzdT5
January 01, 2010 - Thus, all 3 trials had limitations in study design that may
have limited their ability to detect statistically … This body of evidence has several limitations. … Even more important than the limitations of applica-
bility to different populations or interventions … Table 3—Continued
Studies Limitations; Consistency Validity Summary of Findings
Key question 4:
adverse … effects
Adults
11 RCTs No significant limitations
or inconsistencies
Internal: Fair to good
External
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary44/sexually-transmitted-infections-behavioral-counseling-2008
October 15, 2008 - Thus, all 3 of these trials had limitations in study design that may have limited their ability to detect … change in high-risk populations seen in primary care. 20-21 , 28
This body of evidence has several limitations … as a result of our stringency around internal validity and scope of interventions, our findings have limitations … in our review, although they were recently reviewed elsewhere. 34-35
Even more important than the limitations … Key question 4: adverse effects
Adults
11 RCTs
No significant limitations or
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary--html/cardiovascular-disease-screening-using-nontraditional-risk-assessment
July 10, 2018 - study did not meet, or it was unclear whether it met, at least 1 criterion but had no known important limitations … A poor-quality study had a single fatal flaw or multiple important limitations. … however, estimates of even small improvement likely represent an upper bound because of study design limitations … increase CVD events. 45 , 80 However, a small body of evidence with study design and applicability limitations … The evidence report has several limitations.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/food-insecurity-screening
July 28, 2022 - What are the benefits and limitations of these tools (e.g., ease of administration)?