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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-the-disabled-and-elderly-with-multiple-comorbidities-what-is-the-comparative-effectiveness-of-physician-housecalls-on-outcomes-and-total-cost
November 21, 2012 - Alzheimer's disease
Depression and other mental health disorders
Diabetes mellitus
Functional limitations
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effectivehealthcare.ahrq.gov/sites/default/files/epstein.pdf
January 01, 2011 - Incremental change, periodic reassessment
• Awareness of affect and gut feelings
• Attending to context
• Limitations
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-of-genetic-and-other-diagnostic-tests-to-identify-and-treat-intellectual-and-developmental-disabilities-caused-by-genetic-mutations-in-post-natal-to-early-childhood-populations
October 26, 2012 - disorders
Developmental delays, attention-deficit hyperactivity disorder, and autism
Functional limitations
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effectivehealthcare.ahrq.gov/products/cultural-competence/research-protocol
July 08, 2014 - risk of bias inherent in each domain and confidence that the results are believable given the study’s limitations … outcomes of KQ2-5 within each comparison will be evaluated based on four required domains: (1) study limitations … Uncertain
Overall Risk of Bias Assessment
Low
Results are believable taking study limitations … into consideration
Moderate
Results are probably believable taking study limitations into consideration … High
Results are uncertain taking study limitations into consideration
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - risk of bias inherent in each domain
and confidence that the results are believable given the study’s limitations … outcomes of KQ1 within each
comparison will be evaluated based on four required domains: (1) study limitations … Overall Risk of Bias
assessment
Low Results are believable taking study
limitations into consideration … Moderate Results are probably believable
taking study limitations into
consideration
High Results … are uncertain taking study
limitations into consideration
Source: www.effectivehealthcare.ahrq.gov
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-key-questions.pdf
January 01, 2019 - Diagnosis and Treatment of Tethered Spinal Cord
1
Diagnosis and Treatment of Tethered Spinal Cord
Draft Key Questions (KQs)
KQ1: What is the accuracy of radiographic and other diagnostic criteria in diagnosing tethered
spinal cord?
KQ2: What are the benefits and harms of prophylactic surgery for asymptom…
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effectivehealthcare.ahrq.gov/products/chronic-fatigue/research-protocol
May 01, 2014 - The study may be missing information, making it difficult to assess limitations and potential problems … validity of the evaluation, the grades will be reviewed by the entire team of investigators for:
Study limitations … (low, medium, or high level of study limitations)
Consistency (consistent, inconsistent, or unknown
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cerebral-palsy-feeding_research-protocol.pdf
June 12, 2012 - CP) is “a group of permanent disorders of the development of movement and
posture, causing activity limitations … (level 1) to severe head and trunk control limitations that require
extensive use of assisted technology … • GMFCS Level I: walks without limitations.
• GMFCS Level II: walks with limitations. … Limitations include walking long distances and
balancing, but not as able as Level I to run or
jump … • GMFCS Level V: severe head and trunk
control limitations.
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effectivehealthcare.ahrq.gov/products/migraine-prevention/research-protocol
November 03, 2011 - Current Page Topic Timeline Jun. 2, 2011 Topic Initiated Nov. 3, 2011 Research Protocol Jun. 3, 2013 Topic Overview Jun. 11, 2013 Systematic Review Aug. 8, 2013 Disposition of Comments Report Comparative Effectiveness of Preventive Pharmacological Treatments for Migraine
Research Protocol Archived November 3, 2011…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_executive.pdf
July 01, 2012 - Effectiveness of public reporting of health care quality as a
quality improvement strategy (continued)
10
Limitations … and Research Needs
The major limitations of this review are related to the
nature of public reporting … • The research on public reporting also has limitations. … Future research on public reporting could address these
limitations and be more relevant and useful
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
March 01, 2010 - .................................................................................................5
Limitations … Limitations
Although ascertainment of death was virtually complete, we were able to include only
data … Strengths
Despite these limitations, this study has important strengths. … However, we suspect that the limitations noted
above, most of which bias our results against the exposure
-
effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
October 01, 2007 - at-
tributes provides evidence that 6 attributes are strengths of
NEISS-CADES, and 3 are relative limitations … Strengths and Limitations of Surveillance Attributes, National Electronic
Injury Surveillance System-Cooperative … changing needs
Timeliness Speed between reporting steps
Sensitivity Proportion of true cases detected Limitations … NEISS-CADES has several limitations.
-
effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
October 01, 2007 - Objectives: To demonstrate the limitations of RCTs in providing
the information needed by medical decision … Methods: Qualitative description of the limitations of RCTs in
providing the information needed by medical … Limitations of Randomized Trials
The strength of randomized trials lies in the protection
that randomization … Heterogeneity of Treatment Effect
Trials face a second set of limitations for informing
individual patient
-
effectivehealthcare.ahrq.gov/products/epilepsy-medicine/research-protocol
July 01, 2010 - The study may be missing information, making it difficult to assess limitations and potential problems … The risk of bias will be assessed through the evaluation of both design and study limitations. … To assess study design, we will rank studies as having no limitations, serious limitations, or very serious … limitations.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
August 13, 2012 - Some research
questions are easier to operationalize than others, and study limitations should be recognized … stakeholders
to understand the scientific process, including
considerations of bioethics and the limitations … understand other tradeoffs that
were made in the design of the study, in terms of
methodological limitations … need
to have knowledge of the instruments that are
used to measure differences and the accuracy,
limitations … o
Delineate study limitations that stakeholders and
investigators are willing to accept a priori. o
-
effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
October 01, 2007 - ORIGINAL ARTICLE
Studying Prescription Drug Use and Outcomes With
Medicaid Claims Data
Strengths, Limitations … This article reviews strengths, limitations, challenges, and
recommended strategies in using Medicaid … LIMITATIONS, CHALLENGES, AND STRATEGIES
Selecting optimal strategies for research using Medic-
aid claims … involves assessing data quality, understanding
limitations, identifying potential sources of error, … Instrumental variables:
application and limitations. Epidemiology. 2006;17:260–267.
37.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-treatment-ssri_research-protocol.pdf
June 15, 2010 - The classification
of individual studies into categories of study limitations (high or low), will then … sample size, settings, funding sources, treatments (type, dose, duration, and
provider), methodological limitations … Finally, we will attempt to
explore the impact of key methodological study limitations, in particular … approach.14 There are several factors that may decrease the overall strength of the evidence:
1) Study limitations … publication bias for primary outcomes with 10
or more studies using funnel plots, recognizing the limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/research-gaps_research.pdf
February 01, 2013 - ................................................................................................11
Limitations … B2 – This reason should be selected if there are major methodological limitations to the
available studies … Limitations
We chose to apply the framework to 50 systematic reviews to have a number that could be … B2 – This reason should be selected if there are major methodological limitations to the
available studies … B2 – This reason should be selected if there are major methodological limitations to the
available studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
January 01, 2016 - The evidence grade is
usually based on five required domains:
• Study limitations were assessed based … Limitations of the Comparative Effectiveness
Review Process
Assessing the comparative validity of … Limitations of the Evidence Base
The literature that addresses the diagnosis of gout has
numerous limitations … These limitations can be divided into three
categories: study volume, design, and reporting quality. … As we suggested in describing limitations of
the research base, promising algorithms for diagnosis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
April 30, 2014 - Peer Reviewer #1 General Given the limitations of the underlying literature, and the lack of
definitive … Peer Reviewer #4 Discussion The limitations of the review studies are indeed adequately
described. … TEP #1 General Addresses the practicalities, broad implications and limitations very
well. … TEP #5 Discussion I think the key findings and strengths/limitations are clearly stated. Thank you. … TEP #7
Conclusion The limitations are also properly discussed. Thank you.