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Showing results for "limitations".

421. Cad-Women-Diagnosis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
     June 01, 2012 - The limitations of the procedure include the invasive nature of the test and the limited data on the … These limitations are generally considered to be minor when compared with the benefits of the procedure … Limitations of This Review Despite identifying 104 studies (110 articles) that met the inclusion criteria … , this systematic review has several limitations. … Value and limitations of dobutamine stress echocardiography in women with suspected coronary artery

422. bipolar-disorder-treatment-protocol-140623 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
     June 23, 2014 - risk of bias inherent in each domain and confidence that the results are believable given the study’s limitations … outcomes of KQ1 within each comparison will be evaluated based on four required domains: (1) study limitations … Overall Risk of Bias assessment Low Results are believable taking study limitations into consideration … Moderate Results are probably believable taking study limitations into consideration High Results … are uncertain taking study limitations into consideration Source: www.effectivehealthcare.ahrq.gov

423. Making Healthcare Safer IV Rapid Review: Prevention in Adults of Infection With Transmission of Multidrug-Resistant Organisms (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-rapid-research.pdf
     April 01, 2024 - This rapid review had limitations related to the review process. … There were several limitations related to the sources of evidence that were located through the search … Transparent reporting of the methods used and the resulting limitations of the evidence synthesis are … Included Studies Heterogeneity (either quantitative estimate or narrative from the authors) Limitations … Included Studies Heterogeneity (either quantitative estimate or narrative from the authors) Limitations

424. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
     September 01, 2012 - disadvantage of being a retrospective observational data analysis subject to inherent biases and limitations … Second, it was also crucial to avoid the very limitations that the CER identified in the studies evaluated … The process was not without limitations. … Second, it was also crucial to avoid the very limitations that the CER identified in the studies evaluated … The process was not without limitations.

425. Disposition of Comments Report for Stroke Prevention in Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
     August 23, 2013 - We have included discussion of the overall limitations of the evidence based in the future research … We agree and have addressed these limitations and the ESC focused update in the Discussion. … TEP #3 Methods Generally OK Page 18, last para - limitations of c-statistics should be discussed, … The limitations of the review/sudies are described adequately. … The limitations of this CER process have been outlined by the authors.

426. Future Research Needs for First- and Second-Generation Antipsychotics for Children and Young Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
     February 01, 2012 - Despite the aim of the CER1 There are limitations and challenges related to the future research needs … Despite its limitations, the structured process used in this project may prove to be an effective way … Because of several common methodological limitations in the studies that were included in the review … The limitations noted by the CER authors include inadequate blinding of patients and outcome assessors … The nature of the stakeholder process lends itself to certain important limitations.

427. Ced-Topic-Refinement (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-topic-refinement.pdf
     November 01, 2022 - ................ 27 KQ1: What Revisions to the CED Criteria (“Requirements”) May Best Address the Limitations … We also added that there may be limitations imposed by the data vendor. Q. … We considered the strengths and limitations of the existing requirements and we sought to learn what … Key Questions KQ1: What Revisions to the CED Criteria (“Requirements”) May Best Address the Limitations … The inclusion of additional requirements reflects our understanding of the limitations of the existing

428. Assessing Applicability: Interactive Case Study Quiz (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
     May 29, 2025 - Assessing Applicability: Interactive Case Study Quiz Assessing Applicability Interactive Quiz Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov Assessing Applicability Interactive Quiz Why might trials with run-in periods and …

429. Assessing Applicability: Interactive Case Study Quiz (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
     May 29, 2025 - Assessing Applicability: Interactive Case Study Quiz Assessing Applicability Interactive Quiz Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov Assessing Applicability Interactive Quiz Why might trials with run-in periods and …

430. EHC Research Protocol (Amended): Treatments for Acute Episodic Migraine (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
     January 09, 2020 - RCTs start as high SOE. 28 The domains to be used for all KQs will be: the methodological limitations … We will report any limitations in applicability of individual studies in evidence tables and limitations

431. Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
     March 01, 2012 - The inherent limitations present in observational designs (e.g., absence of randomization) are factored … It then defers the issue of study design limitations to assessment of the strength of evidence. … tool(s), the assessment of risk of bias process (summarizing from the protocol), and limitations to … Rating the quality of evidence—study limitations (risk of bias). … Under the meta-scope: potentiatls and limitations of meta-analysis.

432. Rapid Evidence Product Addressing Social Isolation To Improve the Health of Older Adults A Rapid Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-social-isolation-older-adults-final.pdf
     February 01, 2019 - Transparent reporting of the methods used, the resulting limitations of the evidence synthesis, and … These poor-quality studies had multiple methodological limitations including poorly defined interventions … Limitations Limitations of Rapid Review Methodology Rapid reviews take streamlined steps in order … Limitations of Primary Studies We recognize that by limiting our population to only community-dwelling … Discussion Summary Limitations Limitations of Rapid Review Methodology Limitations of Primary Studies

433. Hip-Fracture-Pain Clinician (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
     May 01, 2011 - Effectiveness of Pain Management Interventions Systemic Analgesics and Multimodal Approaches: Studies comparing specific regimens of systemic analgesics or comparing multimodal approaches with standard care were limited, and evidence is insufficient to permit conclusions. ��� Spinal and Epidural Anesthesia: The evi…

434. Tools to (Semi) Automate Evidence Synthesis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/AI-tools-protocol.pdf
     August 15, 2023 - rapid reviews.3 Literature Identification To keep the scope of this project feasible given resource limitations

435. Research Protocol: Improving Cultural Competence To Reduce Health Disparities for Priority Populations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cultural-competence_research-protocol.pdf
     July 09, 2014 - risk of bias inherent in each domain and confidence that the results are believable given the study’s limitations … outcomes of KQ2-5 within each comparison will be evaluated based on four required domains: (1) study limitations … Overall Risk of Bias assessment Low Results are believable taking study limitations into consideration … Moderate Results are probably believable taking study limitations into consideration High … Results are uncertain taking study limitations into consideration picots Binder2 cultural-competence-protocol

436. Disposition of Comments Report for CER 203 ADHD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-203-adhd-disposition-comments.pdf
     January 01, 2018 - The limitations of addressing larger trials within the context of this update is now discussed. … We have now clarified additional limitations of our review. 107. … Peer Reviewer #2 Results In all of the Strength of Evidence tables, in the Limitations columns, the … Does "High" that a study has "high" limitations? … Regarding limitations, can the authors speak to the national/international demographics of ADHD versus

437. Disposition of Comments for CER 163 Appropriate Antibiotics (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
     January 27, 2016 - All studies that are fatally flawed with a combination of multiple and/or serious limitations are … Peer Reviewer #5 (Peer Reviewer) Methods; General Comment The literature search limitations are … Added statement to Limitations section on lack of evidence in children. … The limitations are again addressed along with the gaps in information, and need for further research … At minimum, this issue should be prominently recognised in the limitations.

438. Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rural-telehealth-disposition-comments.pdf
     December 26, 2022 - We have added text about the lack of harms to the limitations of the literature and the implications

439. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-disposition-120104.pdf
     April 01, 2011 - We acknowledged the limitations of using data from systematic reviews in the Discussion (Page 152) … We accept the limitations of using data from systematic reviews, and have added these limitations in … We have acknowledged the limitations of using data from systematic reviews in the discussion section … Peer Reviewer #2 Discussion Implications of the findings are clear enough, limitations adequately … Concerning weaknesses and limitations, it adequately discusses those that they found in analyzing the

440. Outcome Measure Framework Design Document (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/registry-of-patient-registries_research-2014.pdf
     January 01, 2014 - ..................................................................................13 Strengths and Limitations … disorders • Developmental delays, attention-deficit hyperactivity disorder, and autism • Functional limitations … selected outcome measures 19 Effective Health Care Program Research Report Number 43 Strengths and Limitations … The proposed design does have some limitations. … to Designing the OMF Design and Implementation Considerations Proposed OMF Design Strengths and Limitations