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Showing results for "limitations".

321. Disposition of Comments Report for Comparison of Characteristics of Nursing Homes and Other Residential Long-Term Care Settings for People With Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_disposition-comments.pdf
     October 23, 2012 - In reference to this exclusion criterion, we state in the discussion of limitations “…two criteria: … In reference to this exclusion criterion, we state in the discussion of limitations “…two criteria: … The limitations are clearly stated. Thank you. … The limitations of current research is clear, and more work is required in this area. … Peer Reviewer #4 Discussion The limitations of the available research are well described.

322. Prehospital EMS Blood Transfusion and Fluid Interventions for Hemorrhagic Shock (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
     February 04, 2025 - This systematic review will consider the complexity and variety of interventions, the limitations of … included in the review for KQ1–5 that include information about barriers or facilitators (e.g., in study limitations … The study may be missing information, making it difficult to assess limitations and potential problems … If a small number of studies are identified, we will describe their strengths and limitations. … pertaining to barriers and facilitators found in quantitative studies (e.g., implementation challenges, limitations

323. Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/child-growth-development-outcomes-protocol.pdf
     August 19, 2024 - Nutrient Databases Used to Assess Food and Nutrient Intakes Despite the limitations addressed above, … reviewed by at least one other experienced investigator using the following criteria: • Study limitations … (low, medium, or high level of study limitations) o This is the degree to which studies for a given … The strength of the evidence may be downgraded based on the limitations described above. … A practical guide to its calculation, use and limitations.

324. Tonsillectomy for Obstructive Sleep-Disordered Breathing or Recurrent Throat Infection in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
     January 01, 2017 - Guide for Effectiveness and Comparative Effectiveness Reviews.13 We assessed the domains of study limitations … placebo No significant group differences in 2 small studies with medium study limitations 5 RCT ( … Despite these limitations to generalizability, findings reported here are likely widely applicable given … Limitations of the Comparative Effectiveness Review Process We included studies published in English … Limitations of the Evidence Base A relatively large number of studies have been published on tonsillectomy

325. Disposition of comments_Comparative Effectiveness Review No. 242: Radiation Therapy for Brain Metastases (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-disposition-comments.pdf
     June 09, 2021 - On the other hand, findings from nonrandomized studies are also subject to significant limitations … Notably, the evidentiary limitations for particular quality of life outcomes concerns are captured … The limitations are clearly described. No important literature was omitted. Noted. … The limitations of the studies are adequately described. … While we hope an understanding of the strengths and limitations of this evidence can be useful, the

326. Cervical Ripening in the Outpatient Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
     December 18, 2019 - The study may be missing information, making it difficult to assess limitations and potential problems … of the evaluation, the grades will be reviewed by the entire team of investigators for: • Study limitations … (low, medium, or high level of study limitations) 15 o Rated as the degree to which studies for … In accordance with the AHRQ Methods Guidance, if the studies have no limitations (i.e. are low risk … Randomized Clinical Trials and Observational Studies: Guidelines for Assessing Respective Strengths and Limitations

327. Disposition of Comments Report for Evidence Report 215 Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
     January 01, 2020 - Due to space limitations, we have not repeated this in the tables. … TEP # 3 Summary/ Discussion Limitations were clearly described. … Thank you, we mention this in the limitations section. … TEP # 4 Summary/ Discussion— Limitations Limitations: This section adequately summarizes the key … limitations for this review Thank you.

328. Disposition of Comment Report for Wireless Motility Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_disposition-comments.pdf
     May 20, 2013 - One of the limitations of our review was that we excluded studies that did not have a comparison for … TEP 3 Discussion/ conclusion The implications, limitations and future research sections appear to … We need to discuss limitations and so they are listed appropriately. … Yes, thank you, we described this in our limitations and in our results. … The reviewer refers to subpoints in the “Limitations” section of the Executive Summary.

329. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - Page 26 of 230, lines 16-17 states that limitations in study design were based on study design and … are assessed: “Study limitations were rated as low, medium, or high based on study design and the … Limitations of examined studies are presented in a systematic way in the results section. … A separate section on limitations of this review itself is included. … We are very aware of the limitations of RCTs, especially with regard to subgroup analysis.

330. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - Page 26 of 230, lines 16-17 states that limitations in study design were based on study design and … are assessed: “Study limitations were rated as low, medium, or high based on study design and the … Limitations of examined studies are presented in a systematic way in the results section. … A separate section on limitations of this review itself is included. … We are very aware of the limitations of RCTs, especially with regard to subgroup analysis.

331. Disposition of Comments Report for Comparative Effectiveness Review 128 Oral Mechanical Bowel Preparation for Colorectal Surgery (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
     April 30, 2014 - Peer Reviewer #1 General Given the limitations of the underlying literature, and the lack of definitive … Peer Reviewer #4 Discussion The limitations of the review studies are indeed adequately described. … TEP #1 General Addresses the practicalities, broad implications and limitations very well. … TEP #5 Discussion I think the key findings and strengths/limitations are clearly stated. Thank you. … TEP #7 Conclusion The limitations are also properly discussed. Thank you.

332. Gout Executive-2016 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
     January 01, 2016 - The evidence grade is usually based on five required domains: • Study limitations were assessed based … Limitations of the Comparative Effectiveness Review Process Assessing the comparative validity of … Limitations of the Evidence Base The literature that addresses the diagnosis of gout has numerous limitations … These limitations can be divided into three categories: study volume, design, and reporting quality. … As we suggested in describing limitations of the research base, promising algorithms for diagnosis

333. Disposition of Comments Report for Imaging Techniques for Treatment Evaluation for Metastatic Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
     October 01, 2014 - for PET/CT a clear statement about the knowns and unknowns in the literature and the strengths and limitations … We have discussed the strengths and limitations of the PET/CT literature in the third paragraph of the … These are limitations of the current literature, not limitations of the review. … We agree that there are limitations with the current literature.

334. S58 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
     October 01, 2007 - ORIGINAL ARTICLE Studying Prescription Drug Use and Outcomes With Medicaid Claims Data Strengths, Limitations … This article reviews strengths, limitations, challenges, and recommended strategies in using Medicaid … LIMITATIONS, CHALLENGES, AND STRATEGIES Selecting optimal strategies for research using Medic- aid claims … involves assessing data quality, understanding limitations, identifying potential sources of error, … Instrumental variables: application and limitations. Epidemiology. 2006;17:260–267. 37.

335. Ch 1-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
     August 13, 2012 - Some research questions are easier to operationalize than others, and study limitations should be recognized … stakeholders to understand the scientific process, including considerations of bioethics and the limitations … understand other tradeoffs that were made in the design of the study, in terms of methodological limitations … need to have knowledge of the instruments that are used to measure differences and the accuracy, limitations … o Delineate study limitations that stakeholders and investigators are willing to accept a priori. o

336. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-treatment-ssri_research-protocol.pdf
     June 15, 2010 - The classification of individual studies into categories of study limitations (high or low), will then … sample size, settings, funding sources, treatments (type, dose, duration, and provider), methodological limitations … Finally, we will attempt to explore the impact of key methodological study limitations, in particular … approach.14 There are several factors that may decrease the overall strength of the evidence: 1) Study limitations … publication bias for primary outcomes with 10 or more studies using funnel plots, recognizing the limitations

337. Medical Therapies for Children With Autism Spectrum Disorder—An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
     May 01, 2017 - Guide for Effectiveness and Comparative Effectiveness Reviews.8 We assessed the domains of study limitations … These limitations to generalizability likely reflect both the significant heterogeneity of ASD itself … Limitations of the Comparative Effectiveness Review Process We included studies published in English … Limitations of the Evidence Base As noted, studies in the review had small sample sizes and typically … Despite these limitations, investigators have made significant improvements in incorporating commonly

338. S16 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
     October 01, 2007 - Objectives: To demonstrate the limitations of RCTs in providing the information needed by medical decision … Methods: Qualitative description of the limitations of RCTs in providing the information needed by medical … Limitations of Randomized Trials The strength of randomized trials lies in the protection that randomization … Heterogeneity of Treatment Effect Trials face a second set of limitations for informing individual patient

339. S96 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
     October 01, 2007 - at- tributes provides evidence that 6 attributes are strengths of NEISS-CADES, and 3 are relative limitations … Strengths and Limitations of Surveillance Attributes, National Electronic Injury Surveillance System-Cooperative … changing needs Timeliness Speed between reporting steps Sensitivity Proportion of true cases detected Limitations … NEISS-CADES has several limitations.

340. MEDICAL MANAGEMENT OF CONGESTIVE HEART FAILURE AND THE EFFECTIVENESS OF ISOSORBIDE DINITRATE AND HYDRALAZINE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
     March 01, 2010 - .................................................................................................5 Limitations … Limitations Although ascertainment of death was virtually complete, we were able to include only data … Strengths Despite these limitations, this study has important strengths. … However, we suspect that the limitations noted above, most of which bias our results against the exposure