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effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
December 19, 2013 - long-acting and dose),dosing strategies, and characteristics of the clinical setting;
limitations in … KQs I, III, IV: Pain (intensity, severity, bothersomeness), function
(physical disability, activity limitations … The study may be
missing information, making it difficult to assess limitations and potential
problems … validity of the evaluation, the grades will be reviewed by the entire team of
investigators for:
• Study limitations … (low, medium, or high level of study limitations)
• Consistency (consistent, inconsistent, or unknown
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
September 01, 2011 - Unfortunately, digital examination of the cervix in early labor is not
highly reproducible, adding to the limitations … These (methodological and clinical)
limitations are incorporated in grading the
strength of evidence … The limitations of the studies are described but
after listing such issues as bias and other problems … However, we have now added a subsection
discussing limitations of included evidence. … quality of primary studies – so
describing the low strength of evidence and
then again discussing the limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbt-lsr-draft-report.pdf
February 04, 2022 - ES-6
Limitations
Key limitations of the evidence base relate to the limited ability to provide strong … These limitations
affect both the stability and applicability of the findings. … pain has multiple
important limitations. … Despite limitations in the evidence base, our review has several strengths. … There are also some limitations to our review process.
-
effectivehealthcare.ahrq.gov/products/registry-of-patient-registries/standardized-library
February 11, 2019 - To address these limitations, the Agency for Healthcare Research and Quality (AHRQ) developed the Outcome
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/description-of-a-question-or-questions-about-a-health-care-test-or-treatment-o-in-women-with-leiomyomas-who-are-candidates-for-surgery-does-the-use-of-adjunctive-medical-treatment-result-in-better-outcomes-preoperative-adjuva
June 03, 2014 - appropriate management decisions for leiomyomas based on the needs of the individual patient, resources, and limitations
-
effectivehealthcare.ahrq.gov/products/coronary-artery-stenting/research
February 26, 2013 - Limitations
Studies evaluating FFR and IVUS were limited by incomplete outcome reporting, heterogeneity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0398_06-17-2008.pdf
January 01, 2008 - Although both
tests are easy to perform, there are some limitations to using these traditional laboratory
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/how-can-patients-who-have-chronic-diseases-better-prepare-for-critical-illness-and-the-end-of-life-will-a-decision-aid-using-individualized-estimates-of-outcomes-help-shared-decision-making-about-advance-care-planning
December 22, 2011 - Conditions (updated in 2008)
Cardiovascular disease, including stroke and hypertension
Functional limitations
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-urinary-retention_disposition-comments.pdf
September 15, 2014 - I think the authors’ point is better made in the
Limitations section, but I had to read the first sentence … Discussion The implications of the major findings are clearly stated
- The limitations of the review … The limitations are described
adequately. … CUR in men with BPH and no studies of treating
diabetic patients with CUR; therefore, due to space limitations … Under limitations on page 13, I would point out that there is a
lack of standardization with regards
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_disposition-comments.pdf
February 26, 2013 - The authors have explicitly presented the main
points and limitations of the FFR/IVUS. … I agree that because of the limitations in the available
studies gender differences could not be addressed … methods are appropriate, and there is an appropriate
reference to the timing of these studies in the limitations … In particular, limitations in the
current literature with regard to patient populations, clinical
scenarios … The
limitations of the study are clearly stated.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_executive.pdf
March 01, 2017 - inherent in each quality domain and confidence that the
results are believable given the study’s limitations … incidence, or cognitive performance domains
based on four strength of evidence domains: (1) study
limitations … domain having considerable importance.15 Study
limitations were rated as low, moderate, or high according … Limitations of the Review Process
This review encountered several limitations, including but
limited … Other limitations arose
from conceptual and methodologic issues with eligible
studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline_executive.pdf
March 01, 2017 - inherent in each quality domain and confidence that the
results are believable given the study’s limitations … incidence, or cognitive performance domains
based on four strength of evidence domains: (1) study
limitations … domain having considerable importance.15 Study
limitations were rated as low, moderate, or high according … Limitations of the Review Process
This review encountered several limitations, including but
limited … Other limitations arose
from conceptual and methodologic issues with eligible
studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
December 01, 2020 - Limitations
For many interventions, very few or a single trial were available and most were small, … Question (KQ) 1: Opioid Therapy
KQ2: Nonopioid Pharmacologic Therapy
KQ3: Nonpharmacologic Therapy
Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
October 30, 2019 - Peer Reviewer #3 General I may have missed it but I did not see if there were
limitations on the type … Given the methodological
limitations of observational
studies which do not use
propensity matched … Conducting such analyses have
major limitations because of the differences in
study design, patient … We have clarified the limitations
of the evidence exploring CKD
and bleeding risk in both the
key … We agree
however that this section
overlaps with the limitations
and future research section and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-update_disposition-comments.pdf
August 06, 2014 - The authors did a thorough job
discussing limitations of the review and challenges of the
specific … We have added a statement about sample size concerns
to the discussion of the limitations of the evidence … We have noted the lack of
information on providers in the Limitations of the
Evidence Base and Research … We discuss issues with outcome measurement in the
Limitations and Research Gaps sections and note that … We have noted the
limitations of case series in the Methods section.
-
effectivehealthcare.ahrq.gov/products/fatty-acids-cardiovascular-disease/clinician
July 25, 2017 - † The overall evidence grade was assessed based on the ratings for the following domains: study limitations … Gaps in Knowledge and Limitations of the Evidence Base
Numerous differences exist between RCTs and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_clinician.pdf
July 01, 2017 - † The overall evidence grade was assessed based on the ratings for the following domains: study limitations … observational study;
RCT = randomized controlled trial; SBP = systolic blood pressure
Gaps in Knowledge and Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
July 01, 2016 - † The overall evidence grade was assessed based on the ratings for the following domains: study limitations … fecal incontinence; PFMT-BF = pelvic floor muscle training with biofeedback
Gaps in Knowledge and Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
August 01, 2016 - * The overall evidence grade was assessed based on the ratings for the following domains: study limitations … Development of CIN 3 583 ⬌ – 0.89 (0.34 to 2.30) ���
Overview of Clinical Research Evidence (Continued)
Limitations
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_disposition-comments.pdf
July 03, 2012 - Peer Reviewer 1 Discussion The discussion covers very well the limitations of this work, essentially … We have also added a brief discussion of the
limitations of discrimination and calibration for
clinical