-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insulin-blood-sugar-2010_disposition-comments.pdf
January 01, 2010 - Still, we found the following
limitations: The cut-off point for the search is
October 2010. … The limitations of these
analyses should be clearly stated. … These limitations have been added to the
discussion. … The limitations
section of the discussion is inadequate. … We have
added the following clarifications to the limitations
section of the discussion highlighting
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
January 01, 2014 - patient global assessment, and activity limitations (KQ1,2)10
o Adverse effects of the tests, including … The evidence grade is based on five required domains:
study limitations, consistency, directness, precision … SOE of the body of literature on gout diagnostic
methods may be especially challenging, given the limitations … risk of bias and consistency among studies and will narratively describe
particular strengths and limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_disposition-comments.pdf
February 29, 2016 - Therefore, we
downgraded for study limitations. … The evidence was
downgraded for moderate study
limitations. … Therefore, we
downgraded for study limitations. … Therefore, we
downgraded for study limitations. … Therefore, we
downgraded for study limitations.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
December 31, 2022 - The evidence base for Key Question 1 has several limitations. … Limitations of our review methods include single review at the abstract screening level,
which could … and excluded studies likely to have serious
methodological limitations that would invalidate results … Strength of evidence ratings
Finding N Studies, N total
Cohort
Study
Limitations
Directness … Transparent reporting of the methods used and the resulting
limitations of the evidence synthesis are
-
effectivehealthcare.ahrq.gov/sites/default/files/technical-brief-36-patient-engagement-comments.pdf
August 26, 2020 - We added a statement in the limitations
section on the impact of the heterogeneity
of interventions … We noted this in the
Limitations.
17. … We noted this in the Limitations.
18. … We expanded on this concern in the
Limitations and agree that the inclusion
strategy, though broad, … We agree about the limitations you
highlighted in the other comments.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mgmt-hnhc-patients-protocol.pdf
November 07, 2019 - probability of being HNHC because participants commonly
have complex chronic conditions and functional limitations … Patient support services are intended to address common barriers related to resource
limitations, education … Multiple health conditions coupled with additional risk factors (i.e., functional
limitations, behavioral … the MeSH term “multiple chronic conditions”
or similar terms, limited to individuals with functional limitations … qualitative research.38 Our
goal is to have a consistent approach for evaluating the strengths and limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-1.pdf
December 01, 2021 - Limitations in the fair quality trials included baseline
differences between groups and high attrition … The observational studies had important limitations (Appendix tables B-2 and B-3). … Comparison Outcome
Number and
Type of
Studies
Number
of
Subjects Directness Precision
Study
Limitations … Transparent reporting of the methods used and the
resulting limitations of the evidence synthesis are … Preventive Services Task Force (USPSTF).50 Limitations of observational studies was assessed
and summarized
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-227-noninvasive-nonpharm-chronic-pain-comments.pdf
April 16, 2020 - ("Limitations of the Evidence
Base"). … Information on and
discussion of the limitations of the literature and the
review process are described … We believe that the results and discussion
appropriately describes the strenghts and limitations
of … We believe that the results and discussion
appropriately describes the strenghts and limitations
of … The draft report’s findings are significant, particularly with
regard to the challenges and limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
January 01, 2023 - Limitations
The clinical trials included in our aggregate analysis represent a variety of treatment … Versus WBI
Comparative Effectiveness and Harms of PBI Modalities
Financial Toxicity Related to PBI
Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-evidence-summary.pdf
June 01, 2022 - Limitations
The evidence base is small. … 3Amethods_guide_chapter&sort_by=field_product_pub_date
Main Points
Background and Purpose
Methods
Results
Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/presentations-future_research.pdf
April 01, 2012 - criticism of systematic reviews is that, while they generally contain a section describing the
limitations … of the research just reviewed, these limitations sections often are very general (e.g.,
―larger trials … FRN documents aim to delineate where there is an absence of studies
and also to describe limitations … of existing studies to the extent that researchers could improve
upon those limitations. … adjustment for
confounding; sample
size and resources
needed for longer
follow-up are
potential limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - risk of bias inherent in each domain
and confidence that the results are believable given the study’s limitations … outcomes of KQ1 within each
comparison will be evaluated based on five required domains: 1) study limitations … Overall Assessment
Overall Risk of Bias
assessment
Low Results are believable taking study
limitations … into consideration
Moderate Results are probably believable
taking study limitations into
consideration … High Results are uncertain taking study
limitations into consideration
C-difficile-update-protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-agitation-aggression_executive.pdf
March 01, 2016 - Strength of evidence was
evaluated based on five domains: (1) study limitations
(the pattern of risk … Few trials measured similar outcomes, and when
they did, methodological limitations and imprecision … This evidence was insufficient to
draw conclusions for any outcomes, given methodological
limitations … Limitations of Current Literature
Our review reflects the limitations of the available
literature. … These problems can be divided
between broad conceptual issues and methodological
limitations of the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-protocol-amended.pdf
November 18, 2024 - Nutrient Databases Used to Assess Food and Nutrient Intakes
Despite the limitations addressed above, … reviewed by at least one other experienced investigator using the following criteria:
• Study limitations … (low, medium, or high level of study limitations)
o This is the degree to which studies for a given … The strength of the evidence may be downgraded based on the limitations described above. … A practical guide to its calculation, use and limitations.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/improved-cancer-outcomes-protocol_0.pdf
December 01, 2021 - Language of
Publication
English only, due to resource limitations
Abbreviations: KQ=key question … of bias inherent in each domain, and confidence that the results are believable
given the study’s limitations … for KQs 1
through 4 within each comparison, based on five required domains: (1) study strengths and
limitations … certainty around
an estimate); and (5) reporting bias.17 Based on risk of bias, we will rate study limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - NPP_Pain
Table F-1a. Pain severity for neuropathic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug 1 Drug 2 Measure Name Measure Scale Assessment Time (Wk) Time Category Grp 1 Baseline N Grp 1 Baseline Mean Pain Score Grp1 Baseline Variance Type Grp1 Baseline Variance Grp1 Baseline Lower Limi…
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-comments.pdf
May 21, 2020 - • Peer reviewers pointed out potential limitations of our network meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - NPP_Pain
Table F-1a. Pain severity for neuropathic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug 1 Drug 2 Measure Name Measure Scale Assessment Time (Wk) Time Category Grp 1 Baseline N Grp 1 Baseline Mean Pain Score Grp1 Baseline Variance Type Grp1 Baseline Variance Grp1 Baseline Lower Limi…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - NPP_Pain
Table F-1a. Pain severity for neuropathic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug 1 Drug 2 Measure Name Measure Scale Assessment Time (Wk) Time Category Grp 1 Baseline N Grp 1 Baseline Mean Pain Score Grp1 Baseline Variance Type Grp1 Baseline Variance Grp1 Baseline Lower Limi…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/child-obesity-future_research.pdf
March 31, 2010 - There were methodological limitations of the reviewed studies which suggest that future
research might … The methodological limitations in the current evidence base should be addressable, and the
stakeholders … There are some limitations of this project. … There were methodological limitations of the reviewed studies which suggest that future
research might … There are some limitations of this project.