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Total Results: 1,847 records

Showing results for "limitations".

201. Executive summary_Comparative Effectiveness Review No. 276: Diagnosis and Management of Obsessive Compulsive Disorders in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-276-ocd-executive-summary.pdf
     December 01, 2024 - Limitations Multiple small studies reported novel comparisons sizes that did not support graded conclusions … 3Amethods_guide_chapter&sort_by=field_product_pub_date Main Points Background and Purpose Methods Results Limitations

202. Disposition of Comments_Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-disposition-comments.pdf
     July 31, 2024 - We explain in the discussion (Strengths and Limitations of the Evidence Base) why we derived our certainty … Heterogeneity and data limitations (e.g., inconsistent reporting, missing standard deviations or confidence

203. Strategies to De-escalate Aggressive Behavior in Psychiatric Patients (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_disposition-comments.pdf
     July 14, 2016 - We report on the eligible and relevant data that our search identifies, and we note any limitations … Are The limitations of the review/studies described adequately, especially the recognition that the … Discussion/Conclusion TEP #1 The limitations are nicely reviewed and consistent with the systematic … However, we have now made reference to this limitation in our Discussion section in the Limitations … We have discussed this point in our “Limitations of the Systematic Review Process” section.

204. Ch 4-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
     January 01, 2010 - how to determine and then characterize exposure to a factor, given knowledge of the strengths and limitations … At the same time, 52 Developing an Observational CER Protocol: A User’s Guide practical limitations … However, as noted above, there are pragmatic limitations to the ability to measure exposure, and in … Investigators should understand the benefits and limitations associated with the data source being … Investigators should consider the practical limitations of the data and the influence that these limitations

205. Disposition of Comments Report for Allergen-Specific Immunotherapy for the Treatment of Allergic Rhinoconjunctivitis and/or Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_disposition-comments.pdf
     January 01, 2010 - While the reviewer raises concerns about study limitations, we followed the methods described, and assessed … Instead, as described in our methods section, In our grade assignments, we considered the limitations … In our grade assignments, we considered the limitations of each individual study’s quality (using the … To make it clearer we added a statement about this to the executive summary under limitations (Page … The limitations are well described and closely mirror the limitations of prior systematic reviews and

206. Disposition of Comments for Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-disposition-comments-naloxone.pdf
     November 27, 2017 - The methods appear sound and the limitations are well presented. … The Results and Discussion note the limitations of this type of evidence. … Also important are the limitations in follow-up. … We did try to summarize the Limitations succinctly in a single paragraph. … TEP Reviewer #3 Discussion/ Conclusion The limitations are clear.

207. Management of Postpartum Hemorrhage: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_clinician.pdf
     July 01, 2016 - * The overall evidence grade was assessed based on the ratings for the following domains: study limitations … strength of evidence PPH = postpartum hemorrhage; SOE = strength of evidence Gaps in Knowledge and Limitations

208. Effectiveness of Indoor Allergen Reduction in Management of Asthma - Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-reduction-asthma-evidence-summary.pdf
     February 01, 2018 - • Important limitations of the evidence base include population heterogeneity (e.g., patient age … It is important for clinicians to consider the complexity of the patient population and the limitations

209. Disposition of Comments Report for Cardiac Troponins Used as Diagnostic and Prognostic Tests in Patients Wtih Kidney Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_disposition-comments.pdf
     August 11, 2014 - They also did an excellent job outlining the limitations of the studies included in the review and used … The limitations are a reflection of the quality of the available evidence rather than the review itself … Therefore a meta-analysis could have been conducted with the limitations cited. … The limitations section describes some of the issues with troponin which make the studies difficult … The consideration given to the implications and limitations of the available data is very thoughtful

210. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - We have added to the limitations that function was not included as an outcome in prior systematic … We have expanded on the limitations to address the issues with interpreting SMDs, specifically as to … Thank you, we have added this to the limitations of the review process in the discussion. … We have also added to the limitations that there are other safety issues not addressed in this review … Given the imprecision due to the small size of the studies and other limitations, we have changed the

211. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - We have added to the limitations that function was not included as an outcome in prior systematic … We have expanded on the limitations to address the issues with interpreting SMDs, specifically as to … Thank you, we have added this to the limitations of the review process in the discussion. … We have also added to the limitations that there are other safety issues not addressed in this review … Given the imprecision due to the small size of the studies and other limitations, we have changed the

212. Disposition of Comments Report for Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
     January 01, 2014 - TEP Member 4 Executive Summary ES-35, limitations: Other limitations include improved diagnostic … As you suggested, we have included these additional limitations. … Please either remove reference to DISPERSE-2 or provide appropriate context regarding limitations of … This report is lengthy and, given space limitations, we cannot expand the Introduction to include a … Remove reference to DISPERSE-2 or provide appropriate context regarding limitations of that study.

213. Masks-Appendix-Table-B-2-Version-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/masks-appendix-table-b-2-version-2.xlsx
     January 01, 2007 - Inconsistent/Sometimes/Infrequent Mask Use Results: Multiple Mask Layers Versus Single Layer Study Limitations

214. Appendix Table B-2. Observational Studies of Masks in the Community (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-appendix-table-b-2-version-1.xlsx
     January 01, 2007 - Inconsistent/Sometimes/Infrequent Mask Use Results: Multiple Mask Layers Versus Single Layer Study Limitations

215. Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer in Average Risk Adults. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
     February 01, 2012 - Important study limitations include bias in the spectrum of patients self selecting for colonoscopy … “However, there are a few important limitations in scope and timing of this review.” … We have added this point to the “limitations” section of the report. … We did not include a deeper discussion of CISNET’s models, many of the limitations are the same for … "The limitations in this review are primarily from the limitations in the primary research (small body

216. Disposition of Comments for CER 202 Effectiveness and Safety of Bronchial Thermoplasty in the Management of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
     December 14, 2017 - We graded the evidence for individual outcomes based on study limitations, directness, consistency … The strength of evidence for this comparison was low because the study limitations of the two trials … However, the assessment of the strength of evidence involves additional factors: study limitations … The SOE was Low due to medium study limitations, inconsistency, and imprecision. … Peer Reviewer 2 Discussion Implications and limitations were clearly considered. Thank you.

217. Disposition of Comments for CER 201 Effectiveness of Indoor Allergen Reduction in the Management of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
     February 15, 2018 - We agree that these are important limitations. … Peer Reviewer 2 Discussion Implications and limitations were clearly considered. Thank you. … We also have expanded the Discussion section to address these limitations in greater detail. … TEP Reviewer 5 Discussion The implications and limitations are clearly stated. … We also have expanded the Discussion section to address these limitations in greater detail.

218. Breastfeeding and Health Outcomes for Infants and Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol.pdf
     February 01, 2023 - ESR’s last search date and the certainty of the underlying strength of the evidence (based on the limitations … We will note the ESR-reported limitations in the body of evidence and any other important details that … the ESR and will note the concordance or discordance in the consistency, precision, directness, and limitations … The primary domains we will assess as part of our SOE assessment are study limitations, directness, … consistency, and precision as described below: • Study limitations (low, medium, high): The degree

219. Disposition of Comments: Comparative Effectiveness Review No. 237_Integrating Palliative Care in Ambulatory Care of Noncancer Serious Illness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-237-integrating-palliative-care-disposition-comments.pdf
     February 11, 2021 - for implementation or effectiveness were outside the scope of this review; we have expanded on the limitations … This is also noted in the limitations. … This is also noted in the limitations. … throughout the course of illness – and have now come back to this in the discussion and emphasized the limitations

220. CER 215 Executive Summary: Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
     March 01, 2019 - Observational studies had limitations related to their design. … Limitations of the evidence base. … Several limitations pertain to the literature base of this review. … studies were eligible for this review, the small number of trials and smaller samples sizes posed limitations