-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_clinician.pdf
August 01, 2016 - † The overall evidence grade was assessed based on the ratings for the following domains: study limitations … Gaps in Knowledge and Limitations of the Evidence Base
Several gaps and limitations were identified in
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
March 01, 2015 - The magnitude of statistical heterogeneity
was examined by using tau2 owing to limitations of the
I2 … Limitations of the Evidence on Symptom Relief
The body of evidence synthesized for Key Question 1 was … However, the
challenges of synthesizing this evidence extend far beyond
trial quality to limitations … There are several limitations to the evidence base of
nonhormone therapies to consider. … Limitations of the Comparative Effectiveness
Review Process
This review was a large undertaking with
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
July 01, 2010 - The
study may be missing information, making it difficult to assess
limitations and potential problems … This can be
assessed through the evaluation of both design and study limitations. … Studies will be
ranked as having no limitations, serious limitations, or very serious limitations.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/integrating-evidence_methods.pdf
February 01, 2015 - Several tools exist for assessing the methodological strengths and limitations of systematic
reviews … Because the RoB is ultimately collapsed to study limitations
domain categories of high, medium or low … Recommendation: Using strength of evidence domains as a framework (study limitations,
consistency, precision … of primary studies (study limitations), directness, consistency,
precision, and reporting bias. … Using strength of evidence domains as a framework (study limitations, consistency, precision, directness
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
September 01, 2014 - When meta-analysis was not possible (because of clinical
heterogeneity or limitations of reported data … The limitations of the evidence for KQ1a involve
limitations of the available systematic reviews. … Note: In addition to considering study limitations and the domains of directness, consistency, precision … As with KQ1a, the limitations of the evidence for KQ2a
involve limitations of the available systematic … Note: In addition to considering study limitations and the domains of directness, consistency, precision
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
September 29, 2014 - (which is again enumerated in the Limitations of the Evidence Base
section). … Peer Reviewer 1 Discussion/
Conclusion
In the Limitations of the Evidence Base section, the authors … Because the study limitations were predominantly moderate? … Limitations are
adequately described. The future research section is clear. … You can cite the limitations, but at least you will have summarized for readers a range
of risks and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-evidence-summary.pdf
April 01, 2019 - insufficient for the body of
evidence for each Key Question, based on evaluation
of four domains: study limitations … • Adverse effects: Only studies of surgery
explicitly examined harms, but the study
limitations … Limitations
There are important limitations to the evidence
base on the effectiveness of the use of … Other limitations are that the outcomes used to
evaluate telehealth are inconsistent and the best or … There are also limitations to the review process and
decision modeling.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
February 04, 2014 - with the Methods Guide, 12 the general approach to grading the
quality or limitations of individual … Score as one of three
levels, separately by
type of study design:
• Low level of
study limitations … • Medium level of
study limitations
• High level of
study limitations
Directness Required Directness … This may change, however, after assessment of study limitations based
on how the RCTs were conducted … The latter may be moved up to “moderate” when study limitations are
graded as low or medium, based on
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
May 01, 2015 - tongue.1 It variably causes reduced
anterior tongue mobility and has been
associated with functional limitations … Other Feeding Outcomes
With only two comparative studies, both with significant
study limitations, … and measured different
outcomes.
9
Speech Outcomes
Given the lack of good-quality studies and limitations … Also, with only three comparative studies
with small sizes and limitations in the measurement of
outcomes … ankyloglossia (continued)
Outcome;
Number of
Studies and
Quality (Total
Participants)
Study
Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
July 01, 2023 - service and fatigue
topic received a brief update in MHS II, focusing on evaluations of regulatory limitations … Based on several systematic reviews of that literature, the MHS
II review concluded that work hour limitations … Intervention Modifications to work schedules (duration and
structure of hours worked) including:
• Limitations … to total hours worked
• Limitations to maximum shift duration
• Shift patterns including changes to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
January 01, 2023 - Limitations
Key limitations of the evidence base relate to the limited ability to provide strong, … These
limitations affect both the stability and applicability of the findings. … 3Amethods_guide_chapter&sort_by=field_product_pub_date
Main Points
Background and Purpose
Methods
Results
Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
April 01, 2016 - The 15 studies eligible for KQ 2 still had numerous
methodological limitations. … Our results
are, in general, consistent with those in earlier
reviews with respect to limitations of … Publication bias and selective reporting of outcomes
are potential limitations. … Finally, for this review, we excluded non–English-
language studies, based largely on limitations of … Limitations of the Evidence Base
The limited scope and volume of this evidence base
meant that it was
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
October 01, 2021 - c Whole-body exercise versus exercise limited to upper body
Limitations
Key Question 4: Methodological … Key Question 2: Benefits and Harms
Key Question 3: Patient Factors Affecting Benefits and Harms
Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
May 01, 2019 - Low
(Imprecise
findings with
moderate
study
limitations)
Pregnancy
complications:
Miscarriage … Moderate
(Imprecise
findings with
moderate
study
limitations)
ART IVF: Fresh vs. … Low
(Moderate
study
limitations)
Table C. … Low
(Moderate
study
limitations)
Long-term
outcomes: Child
(type 1 diabetes
mellitus)
1 Obs90 … Low (Moderate
study
limitations,
imprecise)
Findings Applicable Across All Infertility
Diagnoses
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
June 22, 2017 - Despite the concerns and limitations
of total DVT as an outcome, we
decided to keep it as an outcome … These
deficiencies are discussed in the
Limitations part of the Discussion. … recommendations
based on these limitations.. … Limitations are
discussed. No important literature that I
know of has been omitted. … The
limitations of the evidence, particularly
related to the gaps in direct
comparative studies of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pilot-projects-supplementing-white-paper.pdf
December 01, 2024 - However, limitations in the literature may
lead to inconclusive findings in EPC systematic reviews ( … ........................................................................................... 11
4.3 Limitations … However, limitations in the evidence base often lead to
inconclusive findings in EPC reports, or findings … Key limitations in the EHR data precluded actionable findings on
efficacy. … Given these
current limitations, it is likely that only a small proportion of EPC evidence review topics
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder-disposition-160504.pdf
December 08, 2015 - reflect various aspects of study
limitations. … We made these limitations
explicit in Appenix E, the summary of
findings tables. … In the
main report and also in the executive
summary we address the limitations. … Information has been added under
limitations. … Adverse events assessment is one of
the main limitations of this body of
evidence.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-270-bimp-executive-summary.pdf
May 01, 2024 - , as was delivery of interventions via digital technology or
telehealth.
4
Limitations … 3Amethods_guide_chapter&sort_by=field_product_pub_date
Main Points
Background and Purpose
Methods
Results
Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-226-labor-dystocia-comments.pdf
May 14, 2020 - CSL might importantly inform
the naïve reader so that they can better appreciate the strengths and
limitations … We have provided similar
details within the
introductory text to help
clarify the limitations of … /causalinferenceseries
It may strengthen the review to include one sentence acknowledging
these limitations … 34
This information about the high numbers of RCTs that were conducted
outside of the US, and the limitations … The discussion/conclusion is much too broad without an inadequate
consideration of the many design limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
September 03, 2019 - We have added a phrase that qualifies the limitations
of the evidence in the Evidence Summary and
Abstract … We have added a sentence to the Methods chapter
describing study limitations. … We state, “When scoring
study limitations, we considered how well the study
design and the study methods … We described the limitations to the body of evidence
throughout the Results chapter, and footnote the … Public Reviewer
#1 (Medicus,
Jennifer [APA])
Discussion/
Conclusion
Limitations of the Evidence