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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
January 01, 2022 - Limitations
Key limitations of the evidence base relate to the limited ability to provide strong, … These limitations
affect both the stability and applicability of the findings. … Important limitations include small
sample sizes, lack of evidence for moderate and long-term use, and … adverse event profile of
cannabinoids used to treat chronic pain, future studies that resolve these limitations … 3Amethods_guide_chapter&sort_by=field_product_pub_date
Main Points
Background and Purpose
Methods
Results
Limitations
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-ki-tep-confidentiality-form.pdf
August 01, 2020 - this may be because of differing opinions or because of other
considerations such as time or resource limitations … this may be because of differing opinions or because of other considerations such as time or resource limitations
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/long-covid-disposition-comments.pdf
January 01, 2022 - Guiding Question 1
describes various existing
published definitions for
long COVID, limitations in … Guiding Question 1
describes various existing
published definitions for
long COVID, limitations in … Guiding Question 1
describes various existing
published definitions for
long COVID, limitations in … We noted high
attrition and other
limitations UK
study. … There are limitations with
regard to reading, auditory and visual processing, and other
cognitive limitations
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-draft-report.pdf
January 31, 2025 - However, this is a small evidence base of eight studies,
which has several limitations when applied … of the Review
There are limitations to this report that are the results of our specific methods or … These limitations are the product of our processes, the tools we
use, and the decisions we make. … As noted in previous sections, this report highlights numerous limitations in the
available studies … This may be in part due to limitations of the literature, as nutrition-based
studies are a challenge
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-269-respectful-maternity-care-summary.pdf
January 01, 2024 - Strengths and Limitations
Many studies included in our review were from cross-sectional surveys from … Most limitations of the evidence base were related to the lack of relevant studies to
evaluate interventions … effectivehealthcare.ahrq.gov/products/search
Main Points
Background and Purpose
Methods
Results
Strengths and Limitations
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_disposition-comments.pdf
August 12, 2016 - Differences between
observational and trial data
are discussed in the
Limitations. … This deficiency was
added to the limitations. … We mention the reporting
deficiency of quantification
of n-3 FA in the Limitations. … This deficiency is mentioned
in the Limitations section. … As we note in the Limitations
section of the Discussion,
there are limitations to the
approach that
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-summary.pdf
August 01, 2023 - Strengths and Limitations
We focused on the best quality evidence directly comparing dose/fractionation … There are limitations to the review and the evidence. … sort_by=field_product_pub_date
Main Points
Background and Purpose
Methods
Results
Strengths and Limitations
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effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-maternal-health-grand-rounds-slides.pptx
January 01, 2023 - Applicability to the U.S. decision-making context
Age and racial diversity of populations
41
41
Limitations … on differences by population subgroups (e.g., by race)
Sparse evidence for many outcomes
42
42
Limitations … reduce unplanned HTN-related hospital readmissions (Low SoE)
56
Key Question 1 (HBPM): Strengths and Limitations … find-a-program-or-service/obstetrics/maternity-care/heart-safe-motherhood
57
Key Question 1 (HBPM): Strengths and Limitations … only) supports use of remote communication of BP measurements versus home BP cuff with a paper log
Limitations
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_disposition-comments.pdf
May 24, 2013 - We agree on the limitations of existing evidence as you identified. … Limitations are adequately described. … Technical Expert #5 Discussion/
Conclusion
Implications and limitations discussed clearly Thank you … We agree on the limitations of existing evidence as you identified. … We understand the limitations inherent in this review.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/musculoskeletal-disorders-imaging_disposition-comments.pdf
November 01, 2011 - Peer Reviewer 3 Methods Limitations of the MAUDE data base should be noted. … the
databases limitations. … A systematic approach for describing the limitations of the studies
overall could be described. … Peer Reviewer 3 Methods,
page 16, line
16
There are limitations of MAUDE in general-- there is no … We have added a cautionary
statement regarding the database’s limitations.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-239-episodic-migraine-comments.pdf
December 29, 2020 - A few
limitations of the evidence base were noted, such as the inability to conduct subgroup
analyses … These
limitations were acknowledged in the discussion section of the report.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
January 01, 2016 - Guide for
Effectiveness and Comparative Effectiveness Reviews”10
and considered all domains: study limitations … A body of evidence was assessed as having high study
limitations if greater than 50 percent of the studies … A body
of evidence was assessed as having low study limitations
if most (51% or greater) of the studies … Bodies of evidence not meeting one of
the above criteria were assessed as having medium study
limitations … The body of evidence was considered high grade if study
limitations were low and there were no problems
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_disposition-comments.pdf
February 11, 2013 - Likewise, future research efforts could be
informed by describing the limitations of the evidence base … TEP #4 Introduction Limitations of the review process (page 160, lines 21-37): I am not clear on
why … N/A
Peer Reviewer
#2
Methods Authors describe limitations of data synthesis due to heterogeneity … N/A
TEP #2 Discussion/
Conclusion
Implications and limitations well stated. … Given the limitations of the data, the report is understandably unable to
endorse specific interventions
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/prostate-cancer-therapies-summary.pdf
September 01, 2020 - Limitations
Our review findings have several limitations including—
• Many randomized trials were … 3Amethods_guide_chapter&sort_by=field_product_pub_date
Main Points
Background and Purpose
Methods
Results
Limitations
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hnhc-disposition-comments.pdf
October 29, 2021 - criteria for the review that encompassed studies of all high-need,
high-cost (HNHC) patients because of limitations … We added an acknowledgement of the time/resource limitations that constrained
the further development … o We expanded the limitations section to include the acknowledgement that,
because we identified HNHC
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effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-238-cervical-ripening-evidence-summary.pdf
March 01, 2021 - estimates [too few patients or events], lack of corroborating evidence [a single study],
and study limitations … Strengths and Limitations
The evidence comparing interventions in the outpatient and inpatient settings … sort_by=field_product_pub_date
Main Points
Background and Purpose
Methods
Results
Strengths and Limitations
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
November 19, 2009 - evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests – uses and limitations … Series
Decision-Analytic Modeling to Evaluate
Benefits and Harms of Medical Tests—
Uses and Limitations … Decision-
analytic modelling to evaluate benefits and harms of medical tests: uses and limitations. … i
Decision-Analytic Modeling to Evaluate
Benefits and Harms of Medical Tests—
Uses and Limitations … ii
Decision-Analytic Modeling to Evaluate
Benefits and Harms of Medical Tests—
Uses and Limitations
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/jensen_eccs2012.pdf
January 01, 2012 - o Limitations/caveats/uncertainties?
o Context (if so, how much?)
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
July 01, 2024 - Explanations for downgrading:
aDowngraded one level for study limitations (one or more trials assessed … bDowngraded one level for inconsistency (effect varied across trials)
cDowngraded one level for study limitations … less than OIS of 400)
gDowngraded one level for imprecision (no or few events)
8
Limitations … 3Amethods_guide_chapter&sort_by=field_product_pub_date
Main Points
Background and Purpose
Methods
Results
Limitations
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/worker-health_disposition-comments.pdf
May 31, 2016 - Text about study limitations (in the
Discussion section) has been edited to
note the concerns about … Limitations well described. I am
not aware of missing studies. … Peer Reviewer
#5
Discussion The limitations are well described. … The authors should add a
discussion of limitations discussed in the response to
question 1 of this … We have added addressed this comment
above and added text to the conclusion
and limitations section