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Showing results for "limitations".

141. Assessing the Applicability of Studies When Comparing Medical Interventions | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-applicability/methods
     May 01, 2020 - clearly highlight important issues relevant to applicability of individual studies in a “Comments” or “Limitations … Make and Report Judgments About Major Limitations to Applicability of Individual Studies Describe impact … Use a summary table for applicability to highlight significant limitations to applicability. … In some instances it may lead to more cautious conclusions due to limitations in applicability. … Make and Report Judgments About Major Limitations to Applicability of Individual Studies Once the appropriate

142. Disposition of Comments for Evidence Report 221 Behavioral Programs for Diabetes Mellitus (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
     September 28, 2015 - We added discussion on these matters in the Limitations of the Comparative Effectiveness Review sections … We agree that the report provided a better description of some of the limitations and these are also … We have added the term “focusing on” in the abstract but word limitations prevent further elaboration … We have revised our comments about the limitations of this method in the discussion. … of the review, limitations of the body of evidence, and future research needs.

143. Disposition of Comments for CER 167 Renal Masses (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/renal-cancer_disposition-comments.pdf
     February 24, 2016 - A discussion of this limitation was added to the report (discussion, limitations of the evidence base … The limitations of the reviews are described adequately. … Space limitations make it difficult to report the full results of each individual study. … Major findings are clearly stated as are the limitations. … This comment is consistent with the limitations we have mentioned in the report.

144. Acs-Pci-Adjunctive-Devices Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
     July 01, 2010 - The study may be missing information, making it difficult to assess limitations and potential problems … This can be assessed through the evaluation of both design and study limitations. … Studies will be ranked as having no limitations, serious limitations, or very serious limitations.

145. Menopause Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - The magnitude of statistical heterogeneity was examined by using tau2 owing to limitations of the I2 … Limitations of the Evidence on Symptom Relief The body of evidence synthesized for Key Question 1 was … However, the challenges of synthesizing this evidence extend far beyond trial quality to limitations … There are several limitations to the evidence base of nonhormone therapies to consider. … Limitations of the Comparative Effectiveness Review Process This review was a large undertaking with

146. Integrating Bodies of Evidence: Existing Systematic Reviews and Primary Studies | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/integrating-evidence/methods
     December 01, 2019 - Several tools exist for assessing the methodological strengths and limitations of systematic reviews. … Because the RoB is ultimately collapsed to study limitations domain categories of high, medium or low … Recommendation : Using strength of evidence domains as a framework (study limitations, consistency, precision … of primary studies (study limitations), directness, consistency, precision, and reporting bias. … Using strength of evidence domains as a framework (study limitations, consistency, precision, directness

147. Progression-Free Survival: What Does It Mean for Psychological Well-Being or Quality of Life? | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/survival-quality/research
     November 01, 2017 - Study design limitations resulted in a poor quality rating for all four studies, and the strength of … Common study limitations included significant data missing not at random, failure to evaluate patient-reported

148. EPC Methods: An Exploration of Methods and Context for the Production of Rapid Reviews | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/rapid-review-production/white-paper
     November 01, 2017 - As the timeframes for products lengthened many limitations were lifted; however, there were still restrictions … scope may be necessary; producers and users need to accept modifications to standard SR methods; and limitations

149. White Paper: Enhancing Systematic Review Methods by Incorporating Unpublished Drug Trials (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
     December 01, 2024 - Limitations ......................................................................................... … harms or burdens, remains unpublished.1,2 Systematic reviews rarely seek unpublished data due to time limitations … Limitations This project has several limitations. … Despite these limitations, the use of FDA reviews may help to overcome the constraints posed by publication

150. Cancer-Pancreas Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
     September 01, 2014 - When meta-analysis was not possible (because of clinical heterogeneity or limitations of reported data … The limitations of the evidence for KQ1a involve limitations of the available systematic reviews. … Note: In addition to considering study limitations and the domains of directness, consistency, precision … As with KQ1a, the limitations of the evidence for KQ2a involve limitations of the available systematic … Note: In addition to considering study limitations and the domains of directness, consistency, precision

151. Integrating Bodies of Evidence: Existing Systematic Reviews and Primary Studies (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/integrating-evidence_methods.pdf
     February 01, 2015 - Several tools exist for assessing the methodological strengths and limitations of systematic reviews … Because the RoB is ultimately collapsed to study limitations domain categories of high, medium or low … Recommendation: Using strength of evidence domains as a framework (study limitations, consistency, precision … of primary studies (study limitations), directness, consistency, precision, and reporting bias. … Using strength of evidence domains as a framework (study limitations, consistency, precision, directness

152. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
     September 29, 2014 - (which is again enumerated in the Limitations of the Evidence Base section). … Peer Reviewer 1 Discussion/ Conclusion In the Limitations of the Evidence Base section, the authors … Because the study limitations were predominantly moderate? … Limitations are adequately described. The future research section is clear. … You can cite the limitations, but at least you will have summarized for readers a range of risks and

153. Ankyloglossia Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
     May 01, 2015 - tongue.1 It variably causes reduced anterior tongue mobility and has been associated with functional limitations … Other Feeding Outcomes With only two comparative studies, both with significant study limitations, … and measured different outcomes. 9 Speech Outcomes Given the lack of good-quality studies and limitations … Also, with only three comparative studies with small sizes and limitations in the measurement of outcomes … ankyloglossia (continued) Outcome; Number of Studies and Quality (Total Participants) Study Limitations

154. head-neck-cancer-update-140204 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
     February 04, 2014 - with the Methods Guide, 12 the general approach to grading the quality or limitations of individual … Score as one of three levels, separately by type of study design: • Low level of study limitations … • Medium level of study limitations • High level of study limitations Directness Required Directness … This may change, however, after assessment of study limitations based on how the RCTs were conducted … The latter may be moved up to “moderate” when study limitations are graded as low or medium, based on

155. Making Healthcare Safer IV: Fatigue and Sleepiness of Clinicians Due to Hours of Service (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
     July 01, 2023 - service and fatigue topic received a brief update in MHS II, focusing on evaluations of regulatory limitations … Based on several systematic reviews of that literature, the MHS II review concluded that work hour limitations … Intervention Modifications to work schedules (duration and structure of hours worked) including: • Limitations … to total hours worked • Limitations to maximum shift duration • Shift patterns including changes to

156. Comparative Effectiveness Review No. 241_Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
     October 01, 2021 - c Whole-body exercise versus exercise limited to upper body Limitations Key Question 4: Methodological … Key Question 2: Benefits and Harms Key Question 3: Patient Factors Affecting Benefits and Harms Limitations

157. No-Touch Modalities for Disinfection of Hospital/Acute Care Settings: A Rapid Evidence Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/no-touch-disinfection/protocol
     July 01, 2020 - However, a description and summary of study limitations including key aspects of study design and conduct … evidence tables with a high level narrative synthesis (including evidence for efficacy) and discussion of limitations

158. Total Worker Health® (TWH) (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/worker-health_executive.pdf
     April 01, 2016 - The 15 studies eligible for KQ 2 still had numerous methodological limitations. … Our results are, in general, consistent with those in earlier reviews with respect to limitations of … Publication bias and selective reporting of outcomes are potential limitations. … Finally, for this review, we excluded non–English- language studies, based largely on limitations of … Limitations of the Evidence Base The limited scope and volume of this evidence base meant that it was

159. Executive Summary - Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
     January 01, 2023 - Limitations Key limitations of the evidence base relate to the limited ability to provide strong, … These limitations affect both the stability and applicability of the findings. … 3Amethods_guide_chapter&sort_by=field_product_pub_date Main Points Background and Purpose Methods Results Limitations

160. Malnutrition in Hospitalized Adults | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/malnutrition-hospitalized-adults/research
     April 01, 2022 - Findings Key Questions Related Findings Clinical and Policy Implications Caveats, Applicability, and Limitations … Findings in Relation to What Is Known Our review underscores many known limitations of research on nutritional … Limitations and Suggestions for Future Research Defining Malnutrition A key challenge for assessing studies … However, use of imaging specifically to assess malnutrition is infrequent and has important limitations … These limitations, along with inconsistencies in the findings for some outcomes and lack of precision