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effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
November 01, 2012 - A single, placebo-
controlled, crossover study of 11 patients found oxycodone
improved leg sensation … like-symptoms may have milder symptoms or other
conditions with symptoms that mimic RLS (e.g., periodic
leg … movement disorders, nocturnal leg cramps, vascular or
neurogenic claudication). … Toward a better definition of the restless legs syndrome:
The International Restless Legs Syndrome … Giving legs to restless
legs: a case study of how the media helps make people sick.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
December 16, 2011 - (Table 2).
23
The International Restless Leg Study group (IRLS) scale is most widely reported. … Epidemiology of restless legs
syndrome: The current status. … Medications for restless legs syndrome in
pregnancy. … Periodic leg movements in sleep and
periodic limb movement disorder: Prevalence, clinical significance … Appendix A:
Ovid MEDLINE Search Strategy for Primary Studies: First Iteration
1 "restless leg
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effectivehealthcare.ahrq.gov/health-topics/leg-injuries-and-disorders
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effectivehealthcare.ahrq.gov/health-topics/restless-legs
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
February 01, 2013 - legs and a
distressing, irresistible urge to move them. … The authors conducted a
systematic review of the effectiveness and harms of treatments for restless leg … Research Gap Questions
for Prioritization
Treatments for Restless Leg Syndrome Future Research
Questions … Strategy:
--------------------------------------------------------------------------------
1 "restless leg … Research Gap Questionsfor Prioritization
Treatments for Restless Leg Syndrome Future Research Questions
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
November 27, 2012 - Treatment for Restless Legs Syndrome. Comparative Effectiveness Review
No. 86. … , leg swelling, or arthritis. … (not leg)
We have added rotigotine and gabapentin enacarbil. … not leg Thank you. … We have replaced all incidents of restless leg
with restless legs.
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effectivehealthcare.ahrq.gov/products/restless-legs/research
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
January 01, 2014 - Future Research Needs
Num
Paper
ber 34
Chronic Venous Leg Ulc
Treatment: Future
er
Research Needs … Future Research Needs Paper
Number 34
Chronic Venous Leg Ulcer Treatment: Future
Research … Chronic
Venous Leg Ulcers: A Comparative
Effectiveness Review of Treatment Modalities. … Ulcers”
Universal definitions of common types of chronic venous leg ulcers are needed. … Ongoing/Recently Completed Studies Related to Treatment ofChronic Venous Leg Ulcers
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
June 01, 2016 - aged 50 years and older who have lumbar central spinal stenosis
and associated moderate-to-severe leg … patients reporting lower extremity discomfort and paresthesias
while standing or walking and nocturnal “leg … position).1 There is clear evidence
that the risk for acquiring LSS and associated lower back and leg … spinal
stenosis on magnetic resonance imag-
ing or computed tomography, and had
moderate-to-severe leg … The sec-
ondary outcomes were improvement in
function and leg pain at 3 weeks; the pro-
portions of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
January 01, 2014 - : A Comparative
Effectiveness Review of Treatment Modalities
Executive Summary
Background
Venous leg … Venous leg ulcer:
incidence and prevalence in the elderly. … The effect of amelogenins
(Xelma) on hard-to-heal venous leg ulcers. … Evaluating a superabsorbent
hydropolymer dressing for exuding venous leg ulcers. … Topical treatment of non-
healing venous leg ulcers by cellulose membrane.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment_research-protocol.pdf
September 13, 2012 - Background and Objectives for the Systematic Review
Background
Venous leg ulcers are extremely … • We will include studies of patients with chronic venous leg ulcers. … ulcer”[tiab] OR “leg ulcers”[tiab] OR “leg ulceration”[tiab] 4478
#9 “venous ulcer”[tiab] OR “venous … ulcer”[tiab] OR “leg ulcers”[tiab] OR “leg ulceration”[tiab] 4484
#9 “venous ulcer”[tiab] OR “venous … ulcer”[tiab] OR “leg ulcers”[tiab] OR “leg ulceration”[tiab] 4488
#9 “venous ulcer”[tiab] OR “venous
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effectivehealthcare.ahrq.gov/products/venous-ulcers-treatment-future/research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0215_01-06-2010.pdf
January 01, 2010 - 8-13-10
1
Results of Topic Selection Process & Next Steps
Treatment of restless legs … Nomination
Summary:
The nominator questions whether there are any effective treatments for restless legs … Staff-Generated PICO
Population(s): Patients with restless legs syndrome
Intervention(s): Dopaminergic … )
Restless legs syndrome (RLS) is a common neurological disorder characterized by an irresistible … inactivity, particularly in the evening, and can be described as burning, itching,
Treatment of Restless Legs
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effectivehealthcare.ahrq.gov/products/restless-legs/research-protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-imaging_clinician.pdf
April 01, 2016 - The primary outcome was disability re-
lated to back or leg pain as measured
by the modified Roland-Morris … Secondary patient-reported outcomes
included average back pain intensity in
the past week, average leg … health
status, and falls.
»» Patients in the early radiograph group
had lower numerical scores for leg … However, the difference in
leg pain was less than 1 point between
groups and was well below any thresh … difference.
»» Patients with early MRI/CT, when com-
pared with the no early imaging group,
reported lower leg
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effectivehealthcare.ahrq.gov/products/restless-legs-future/research
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
January 31, 2013 - IC is defined as leg muscle discomfort provoked by exertion that is relieved
with rest, while atypical … claudication (also called atypical leg discomfort ) is defined as lower
extremity discomfort that is … KQ 2: In adults with symptomatic PAD (atypical leg symptoms or IC):
a. … Bypass versus
Angioplasty in Severe Ischaemia of the Leg (BASIL) trial in perspective. … ulcer”[MeSH] OR “leg ulcer”[tiab] OR (leg[tiab]
AND ulcer[tiab]) OR “leg ulcers”[tiab] OR (leg[tiab
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-draft-report-appendix-d.xlsx
January 01, 2019 - ) vs. 3.38 (2.99 to 3.76)
2 years (n=121 vs. 119): 3.67 (3.25 to 4.08) vs. 3.33 (2.92 to 3.74)
NRS leg … Austevoll, 2021 Moderate ZCQ symptom severity
5 year: 2.26 (2.13 to 2.39) vs. 2.43 (2.29 to 2.56)
NRS leg … 2.8) vs. 7.4 (2.6) NR One or two adjacent vertebral levels Pseudoclaudication required in one or both legs … vs. 41/59 (69)
2 level, n (%): 21/60 (35) vs. 18/59 (31) Pseudoclaudication required in one or both legs … B
VAS Leg pain
There was no significant interaction between race (white vs non-white) and treatment
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-substitute_0.pdf
October 03, 2019 - Chronic wounds include pressure ulcers,
diabetic foot ulcers, and venous leg ulcers. … intractab* OR 'non-healing' OR
nonhealing OR persisten*)):ab,ti OR ((bed OR foot OR feet OR diabet* OR leg … OR
legs OR pressure OR venous) NEAR/2 (sore* OR ulcer*)):ab,ti OR (diabet* NEAR/2
(feet or foot)): … Criteria
Population Human subjects in whom a chronic wound
(pressure ulcer, diabetic foot ulcer, venous leg … ulcer, or arterial leg ulcer) lasting more than 30
days without healing has been diagnosed
Animal
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cerebral-palsy-feeding_research-protocol.pdf
June 12, 2012 - • Diplegia/diparesis usually indicates the
legs are affected more than the arms;
primarily affects … • Hemiplegia/hemiparesis indicates the arm
and leg on one side of the body is affected. … • Paraplegia/paraparesis means the lower
half of the body, including both legs, are
affected. … This could be both arms and a
leg, or both legs and an arm. … Often, the arms and legs are
affected.