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61. Comparative Effectiveness of Treatment for Phenylketonuria | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/phenylketonuria/research-protocol
    December 01, 2019 - This deficiency leads to a buildup of an essential amino acid called phenylalanine (Phe) in the blood … After reviewing a sample of relevant articles, the Methods and Content Leads will design the data-extraction … phase of the study, the Project Coordinator on a weekly basis will report to the Methods and Content Leads … usually results from a deficiency of a liver enzyme known as phenylalanine hydroxylase (PAH), […which] leads

62. PEPTIC ULCER #11 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - AHRQ did not directly participate in horizon scanning, assessing the leads for topics, or providing … Since that implementation, review of more than 18,000 leads about potential topics has resulted in … Moderately high Discussion Compared with other priority areas, we have identified relatively few leads … a small patient population, limited treatment options are available, and the main treatment, PN, leads

63. #05 DEPRESSION (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
    January 01, 2012 - AHRQ did not directly participate in horizon scanning, assessing the leads for topics, or providing … Since that implementation, more than 11,000 leads about topics have resulted in identification and … procedures: lead placement and neurostimulator implantation. 15 The surgeon implants electrode leads … at the scalp and down the neck to the chest. 15 To treat OCD, a neurosurgeon implants electrode leads … in the anterior limb of the internal capsule (AIC) and connects the leads to the neurostimulator.

64. #05 DEPRESSION (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/depression_hi_impact.pdf
    October 01, 2014 - AHRQ did not directly participate in the horizon scanning, assessing the leads for topics, or provide … Since that implementation, more than 7,000 leads about topics have resulted in identification and tracking … The electrode leads connect to the neurostimulator through insulated extension wires, which are tunneled … of the internal capsule (AIC, also called the ventral capsule/ventral striatum) and connects the leads … In most cases, the new device can be connected to the existing electrode leads. 1 Currently, Medtronic

65. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
    January 01, 2010 - After reviewing a sample of relevant articles, the Methods and Content Leads will design the data collection … The abstractor(s) and the co-Leads will reassess each retained article against the inclusion/exclusion … Coordinator will report the number of abstracts and articles out for review to the Methods and Content Leads

66. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
    June 01, 2010 - The abstractor(s), the content leads and content experts, the library scientists, and the investigators … will report on 1) the number of abstracts and articles being reviewed by the methods and content leads … While developing the report, the content leads in consultation with epidemiologists and biostatisticians

67. #06 Developmental Delays ADHD, and Autism (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - AHRQ did not directly participate in horizon scanning, assessing the leads for topics, or providing … Since that implementation, review of more than 16,000 leads about potential topics has resulted in … intensive scanning for interventions and innovations in this priority area, we find a paucity of leads

68. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
    November 01, 2016 - AHRQ did not directly participate in horizon scanning, assessing the leads for topics, or providing … Since that implementation, review of more than 21,000 leads about potential topics has resulted in … In the past 12–15 months, even fewer topics have met criteria for tracking because so few of the leads

69. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
    November 01, 2016 - AHRQ did not directly participate in horizon scanning, assessing the leads for topics, or providing … Since that implementation, review of more than 24,500 leads about potential topics has resulted in … In the past 12–15 months, even fewer topics have met criteria for tracking because so few of the leads

70. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
    December 09, 2009 - After reviewing a sample of relevant articles, the Methods and Content Leads will design the data collection … The abstractor(s) and the co-Leads will reassess each retained article against the inclusion/exclusion … Coordinator will report the number of abstracts and articles out for review to the Methods and Content Leads

71. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
    December 01, 2011 - One trial showed that supplementing fluoxetine therapy with eszopiclone leads to improved sleep. … The strength of evidence that trazodone leads to higher rates of somnolence than comparator drugs is … The strength of evidence is low that paroxetine IR leads to higher rates of nausea than paroxetine CR … Comparative risk of weight High Results from seven trials indicate that mirtazapine leads to higher … Low One trial provides evidence that paroxetine IR leads to higher rates of nausea than paroxetine CR

72. Training and Support for Patients and Consumers Engaged in Research (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/bonoff-text.pdf
    January 01, 2000 - Training and Support for Patients and Consumers Engaged in Research …

73. Slide 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/ahrq_community_forum_webinar_bonoff.pdf
    January 01, 2000 - Slide 1 Presented By: Amy Bonoff Training and Support for Patients and Consumers Engaged in Research Training & Support • Training and continued learning opportunities are a key element for success • Methods to support patient and consumer involvement are evolving – NBCC Project LEAD – FDA Patie…

74. PEPTIC ULCER #11 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - AHRQ did not directly participate in horizon scanning, assessing the leads for topics, or providing … Since that implementation, review of more than 18,000 leads about potential topics has resulted in … Compared with other priority areas, we have identified relatively few leads and topics that meet inclusion … a small patient population, limited treatment options are available, and the main treatment, PN, leads

75. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs-iv-nursing-staff-shortages.pdf
    October 01, 2024 - .5 When acute care units are short staffed, each nurse is forced to care for more patients, which leads … Missed nursing care leads to higher mortality, lower patient satisfaction, and adverse events like

76. Nitrous Oxide for the Management of Labor Pain | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/labor-nitrous-oxide/research-protocol
    December 01, 2019 - After reviewing a sample of relevant articles, the Methods and Content Leads will design the data collection … The Methods and Content Leads and content experts will review extraction forms against the original articles … Coordinator will report the number of abstracts and articles out for review to the Methods and Content Leads

77. Management of Colonic Diverticulitis | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/diverticulitis/research
    January 01, 2022 - There is low SoE that CT imaging leads to appropriate management decisions and that misdiagnoses on CT

78. Fatty Liver Disease | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/fatty-liver-disease
    If the cirrhosis leads to liver failure, you may need a liver transplant .

79. Comparative Effectiveness of Venous Thromboembolism (VTE) Prophylaxis in Orthopedic Surgery | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/blood-clots-hip-knee-surgery/research-protocol
    December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

80. Disclosure Policy and Form (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/epc-disclosure-policy-form.pdf
    March 01, 2023 - Either the EPC Director or the designated Lead Investigator leads the Core Team and is the primary person … Either the EPC Director or the designated Lead Investigator leads the Core Team and is the primary person