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21. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0443_06-01-2011.pdf
    January 01, 2011 - appropriate treatment selection, reduced need for reoperation, harms from inappropriate tumor staging leading

22. Computerized Definitions Showed High Positive Predictive Values for Identifying Reasons for Hospitalizations in a Medicaid Population with Rheumatoid Arthritis (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
    October 01, 2008 - Purpose: Computerized definitions are used to identify serious infections and congestive heart failure leading … Conclusion: These findings suggest that computerized definitions can identify common conditions leading … Discussion Our findings indicate that computerized definitions can identify common conditions leading … Our study demonstrates that computerized definitions can identify selected common conditions leading … Positive predictive value (PPV) of computerized definitions for events leading to hospitalization in

23. PowerPoint Presentation (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/krishnan_ahrq-mcda-presentation.pdf
    August 27, 2012 - Disease (COPD) • Key health condition in US – Most common lung disorder • 24,000,000 persons – 3rd leading … cause of death • Deaths rising • Heart disease, Cancer, COPD, CVA, Accidents – 3rd leading cause

24. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0119_06-17-2009.pdf
    January 01, 2009 - deficiency of a liver enzyme involved in the breakdown of the essential amino acid phenylalanine, leading

25. A Bayesian Missing Data Framework for Multiple Continuous Outcome Mixed Treatment Comparisons | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/indirect-comparisons/research-2013
    January 10, 2013 - Ignoring missing data or correlation between outcomes can produce biased MTC estimates leading to high

26. Arthritis and Nontraumatic Joint Disease (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - gout, which can result in monosodium urate crystals forming and depositing in and around joints, leading … Uncontrolled gout can lead to accumulation of tophi, leading to chronic pain, joint erosion, and limited … By selectively inhibiting URAT1, lesinurad is thought to promote urinary excretion of uric acid leading … However, few agents are available to address the underlying mechanisms leading to gout, the experts … Still, few agents are available to address the underlying mechanisms leading to gout, the experts thought

27. Topic Suggestion Description | Effective Health Care Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/pico-populations-breastfeeding-infants-6-months-or-less-with-ankyloglossia-interventions-frenotomy-frenectomy-or-frenulotomy-comparators-breastfeeding-management-without-surgical-intervention-outcomess-successful-exclusive-br
    March 14, 2013 - extend period of breastfeeding with normalized suckle to swallow pattern), and increase in milk transfer leading … complications of untreated ankyloglossia in the breastfeeding infant may include problems with milk transfer leading

28. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
    February 01, 2015 - Similarly, researchers hypothesize that neurofibrillary tangles adversely affect neuron function, leading … or misdiagnosed; however, with disease progression, beta-amyloid proteins accumulate abnormally, leading … Recent National Center for Health Statistics data rank AD as the sixth leading cause of death among … Because relevant manufacturers are not leading clinical trials or formally pursuing expanded AD-related … (Bloomington, MN), and the Alzheimer’s Disease Cooperative Study (La Jolla, CA) are among groups leading

29. Treatment for Glaucoma: Comparative Effectiveness | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/glaucoma-treatment/research
    April 12, 2012 - Structured Abstract Objectives Glaucoma is a leading cause of visual impairment and blindness worldwide

30. Topic 0438 Risk stratification and CAD NSD FINAL_SJ-2 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0520-131115.pdf
    November 15, 2013 - Despite recent decreases in mortality, heart disease remains the leading cause of death in the US for

31. Evidence Summary: Comparative Effectiveness Review No. 236 Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
    April 01, 2021 - Brexanolone probably improves depressive symptoms; it may increase the risk of sedation or somnolence, leading … or within 4 weeks of birth, brexanolone may be associated with the risk of sedation or somnolence leading

32. Supporting Patient and Consumer Involvement in Patient-Centered Outcomes Research (Video Presentation) | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/stakeholders-engagement-others/research
    October 13, 2011 - Branson works with leading consumer advocacy and support organizations to identify and nominate qualified

33. Hypofractionated Radiation Therapy for Localized Prostate Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-key-question.pdf
    December 19, 2023 - eight men in the United States will develop prostate cancer in his lifetime1; prostate cancer is the leading … among men (age-adjusted incidence rate of 113.4/100,000 men between 2016 and 2020) and the second leading

34. Antenatal Care | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/antenatal-care
    April 07, 2020 - frequency of prenatal visits are very much based on tradition without a significant amount of evidence leading

35. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0095_04-10-2009.pdf
    January 01, 2009 - )  Cardiovascular disease is the leading cause of mortality for women in the US.

36. Evidence Summary_Models of Care That Include Primary Care for Adult Survivors of Childhood Cancer: A Realist Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/models-care-adult-survivors-childhood-cancer-evidence-summary.pdf
    February 01, 2022 - care and resources to achieve these intermediate outcomes for survivors and providers, ultimately leading … Limitations Evidence on adult survivors of childhood cancer was limited leading us to consider studies

37. Use of Analytic Hierarchy Process to elicit stakeholder preferences for prioritizing research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/mcda-krishnan.pdf
    August 27, 2012 - (COPD) • Key health condition in US – Most common lung disorder • 24,000,000 persons – 3rd leading … cause of death • Deaths rising • Heart disease, Cancer, COPD, CVA, Accidents – 3rd leading cause

38. Management of Suicidal Thoughts in Youth (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-key-question_0.pdf
    January 01, 2019 - Management of Suicidal Thoughts in Youth Draft Key Questions Background Suicide is the second leading

39. Executive Summary: Healthcare Industry Waste and Use of Life (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-executive-summary.pdf
    September 01, 2023 - The leading limitation reported in the LCA studies was the lack of data and the need to estimate or approximate … Limitations: The leading limitation reported in the LCA studies was the lack of data and the need to

40. Topic 0533 Postpartum Hemorrhage NSD FINALsj (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0652-131114.pdf
    May 15, 2013 - more than 500 mL following vaginal delivery or more than 1000 mL following cesarean delivery, is the leading