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61. Topic 0523 Muscle Invasive Bladder Cancer NSD FINAL_SJ (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0620_131115.pdf
    March 13, 2013 - concern for patients and providers is the potential malignant spread to distant sites which would lead

62. Treatments for Chronic Pain | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/treatments-for-chronic-pain/overview
    April 16, 2020 - Treatments for Chronic Pain Overview April 16, 2020 Chronic pain affects millions of adults in the United States. It is the leading cause of disability and significantly impacts physical and mental functioning and quality of life. Chronic pain is often defined as pain lasting 3 months or longer or per…

63. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
    January 01, 2011 - Effective Health Care Topic Number: 0407 Document Completion Date: 02-14-12 1 Results of Topic Selection Process & Next Steps  Primary diagnosis and staging of pancreatic cancer will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, c…

64. Closing the Quality Gap Series: Quality Improvement Interventions to Address Health Disparities | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/disparities-quality-improvement/research-protocol
    February 22, 2012 - The team Methods Lead and Lead Scientist will test the abstract review form on multiple articles before … undergo several revisions following input from the technical expert panel and testing by the team Methods Lead … and Scientific Lead. … The Methods Lead, the Lead Scientist, and the content experts will review those data-extraction forms

65. Early Imaging for Back Pain and Clinical Outcomes in Older Adults: A Brief Summary of Findings and Key Points for Clinician-Patient Discussions | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/back-pain-imaging/clinician
    May 13, 2016 - Approximately 90 percent of older adults have incidental findings on spine imaging studies, which may lead … It is possible that imaging might reveal incidental findings that could lead to subsequent interventions

66. Back-Pain-Imaging Clinician (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-imaging_clinician.pdf
    April 01, 2016 - proximately 90 percent of older adults have incidental findings on spine imaging studies, which may lead … take years to develop. »» It is possible that imaging might reveal incidental findings that could lead

67. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - DEMENTIA INCLUDING ALZHEIMER'S #04 AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 04: Dementia (Including Alzheimer’s Disease) Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road Rockvil…

68. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0313_02-09-2009.pdf
    January 01, 2009 - of urinary stone disease were identified from the US, it appears that a review on this topic could lead

69. Topic Suggestion Description | Effective Health Care Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/pico-populations-breastfeeding-infants-6-months-or-less-with-ankyloglossia-interventions-frenotomy-frenectomy-or-frenulotomy-comparators-breastfeeding-management-without-surgical-intervention-outcomess-successful-exclusive-br
    March 14, 2013 - and non-exclusive breastfeeding, both have adverse effects on child and maternal health outcomes and lead

70. Arthritis and Nontraumatic Joint Disease (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Uncontrolled gout can lead to accumulation of tophi, leading to chronic pain, joint erosion, and limited … AstraZeneca to acquire Ardea Biosciences for $1 billion (net of existing cash) including lead product

71. Models of Cancer Survivorship Care | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/cancer-survivor-care-transition/technical-brief
    March 18, 2014 - Although competing considerations and incentives may lead oncologists or oncology providers in many instances

72. Topic 0509 Home-based Primary Care Interventions NSD FINAL SJ-2 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0599-131115.pdf
    June 20, 2013 - Context from Nomination: The Independence at Home demonstration currently being conducted by CMS may lead

73. Breathing Exercises and/or Retraining Techniques in the Treatment of Asthma: Comparative Effectiveness | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/asthma-treatment/research
    September 10, 2012 - Abstract Objectives To examine evidence for whether breathing exercises and retraining techniques lead

74. Findings of Bayesian Mixed Treatment Comparison Meta-Analyses: Comparison and Exploration Using Real-World Trial Data and Simulation | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/bayesian-mixed-treatment/research
    January 31, 2013 - those of frequentist indirect methods may differ for a small proportion of comparisons, which could lead

75. S131 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
    October 01, 2007 - Studying mixed prevalent and incident user cohorts will lead to under-ascertainment of early events. … hyperlipidemia) and because these characteristics are difficult to assess in claims data, they may lead … comparison group makes members of the comparison group seem healthier than they really are and may lead … This approach may lead to a bias towards the null. … Selective prescribing can lead to over-estimation of the benefits of lipid-lowering drugs.

76. Summary Variables in Observational Research: Propensity Scores and Disease Risk Scores | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/observational-research-scores/research
    May 15, 2012 - Accounting for these differences, which may lead to observed associations of treatment and outcome even … If some patient characteristics that lead to the choice of one therapy over another are not measured … Stratification on numerous variables will quickly lead to many strata that do not have both exposed and … Since some adverse effects of statins, such as rhabdomyolysis, can be severe and lead to substantial … Though the question "does rosuvastatin lead to more rhabdomyolysis than other statins?"

77. Comparing the Effectiveness of Treatment Strategies for Primary Open-Angle Glaucoma | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/glaucoma/abstract
    November 09, 2011 - Comparing the Effectiveness of Treatment Strategies for Primary Open-Angle Glaucoma Abstract Archived November 9, 2011 Topic Abstract Background: In the United States, the prevalence of open-angle glaucoma for all adults 40 years old and older is estimated to be 1.86%. 1 Open-angle glaucoma affect…

78. Topic Suggestion Description | Effective Health Care Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/management-vestibular-schwannomas
    June 11, 2021 - Monitoring Question 1: Does intraoperative facial nerve monitoring during vestibular schwannoma surgery lead … The CNS maintains in-house infrastructure to lead, promote, and support the creation and methodological

79. Ch 2-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
    January 01, 2011 - to death) are less likely to be treated with a multitude of preventive treatments,8 frailty would lead … While procedures to select subjects usually lead to confounding that can be controlled for, factors … is the potential that treatments will be assessed differently for cases and controls, which will lead … Sampling of controls from all those who enter the cohort (i.e., at baseline) may lead to biased estimates … Thus both methodological and clinical relevance considerations lead to the same principle for study

80. Data Points #18: Use of and access to health care by Medicare beneficiaries with diabetes: impact of diabetes type and insulin use, 2007-2011 | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/diabetes-medicare-use/research
    January 29, 2014 - take into account the number of providers seen when assessing whether attempts at care coordination lead