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461. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - #06 Developmental Delays ADHD, and Autism AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 06: Developmental Delays, ADHD, and Autism Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither…

462. S38 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s38.pdf
     October 01, 2007 - same intervention can enhance compliance, and conversely assignment to different interventions can lead

463. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
     January 01, 2007 - Two trials indicated that a combination treatment of two biologic DMARDs can lead to substantially higher

464. Observed Association Between Antidepressant Use and Pneumonia Risk Was Confounded by Comorbidity Measures (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-seniors-pneumonia_research.pdf
     May 01, 2008 - This signal arose in the context of a systematic process to screen for iatrogenic factors that may lead

465. Microsoft Word - ehcrr#2toCSI.doc (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
     August 01, 2007 - study population in age and race/ethnicity suggest that any failure to adjust for such covariates will lead … intention- to-treat because of the known potential for drug intolerance or treatment failure that may lead

466. Disposition of Comments Report for Oral Contraceptive Use for the Primary Prevention of Ovarian Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
     June 07, 2013 - decreases protection for ovarian, colorectal, and endometrial cancers, underestimating the upper tail may lead … decreases protection for ovarian, colorectal, and endometrial cancers, underestimating the upper tail may lead … cardiovascular disease demonstrated that even very consistent data from observational studies can lead … (2) If the conclusions of the analysis could lead to the use of OCs for ovarian cancer prevention … The incident cases of what diseases are counted to make the comparison “unfavorable” yet lead to a

467. Autism Spectrum Disorder — An Update | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/autism-update/research-protocol
     September 20, 2013 - cognition and language have led to the suggestion that beginning intensive therapy at an earlier age may lead … Individuals engage in interventions, which may lead to specific outcomes (KQ 1). … exclude case series, as additional case series (studies without a comparison group) are unlikely to lead

468. Assessing the Impact of Indexing Performance Measure Codes on the Perceived Value of EPC Reports to Health Systems (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-assessing-impact.pdf
     September 01, 2018 - DeLayo, MS, APRN, ACNP-BC is the Interim Director of Quality and Lead Quality Improvement Advanced Practice … this latter case, making it two categories (most or moderate) instead of one (more relevant) might lead … Conclusions The creation of supplemental tables that lead to rapid identification of quality measures

469. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
     June 01, 2010 - gaps with initial consideration of the review questions or after discussion with content experts, may lead … usually require assessment at the individual study level: their consideration a priori will not likely lead … should be considered within and across studies; these flaws potentially invalidate the results (e.g., lead

470. Template for Reports Developed (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-nomination_methods.pdf
     November 01, 2012 - Development Team Topic nomination development is typically conducted by a small team consisting of a team lead … The team lead is often a doctorally- trained person with a strong epidemiology, health services research … A poorly defined PICO can lead to development of a topic that may miss important populations, lack … A vague PICO also presents scoping challenges and may lead to a review that is too inclusive or too

471. Local Therapies for Unresectable Primary Hepatocellular Carcinoma: Comparative Effectiveness Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/liver-cancer-therapy/research-protocol
     March 20, 2012 - This may in turn lead the way for the complete ablation of larger size tumors. 23 Direct comparisons

472. Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/alcohol-misuse-drug-therapy/research-protocol
     April 26, 2013 - Current Page Topic Timeline Sep. 20, 2012 Topic Initiated Apr. 26, 2013 Research Protocol May. 13, 2014 Systematic Review Sep. 22, 2014 Disposition of Comments Report Oct. 18, 2017 Surveillance Report Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings Research Protocol Archived April 26, …

473. Alcohol-misuse-drug-therapy-140326 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
     January 27, 2012 - Alcohol-misuse-drug-therapy-140326 …

474. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_june_2012.pdf
     January 01, 2012 - DEMENTIA INCLUDING ALZHEIMER'S #04 AHRQ Healthcare Horizon Scanning System – Potential High Impact Interventions Report Priority Area 04: Dementia (Including Alzheimer’s Disease) Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Ro…

475. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - DEMENTIA INCLUDING ALZHEIMER'S #04 AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 04: Dementia (Including Alzheimer’s Disease) Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road R…

476. Liver-Cancer-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
     November 28, 2012 - This may in turn lead the way for the complete ablation of larger size tumors.23 Direct comparisons

477. PHARMACO-EPIDEMIOLOGIC METHODS FOR A STUDY OF (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-cardiovascular-elderly_research.pdf
     February 01, 2009 - Hypoperfusion has been shown to lead to microinfarcts in dementia patients and investigators have proposed … for any improvements in the prevention of cardiac or cerebrovascular events, which could otherwise lead

478. Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/alcohol-pharma-final-protocol.pdf
     January 01, 2023 - unclear but acamprosate is thought to antagonize glutamatergic N-methyl-D-aspartate receptors and lead … An updated review could lead to increased and more effective dissemination and has the potential to

479. Efficacy and Safety of Screening for Postpartum Depression | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/depression-postpartum-screening/research-protocol
     March 09, 2012 - criteria for major depression improves outcomes. 3,4,23 If a diagnosis of “minor depression” does not lead … As noted above, if treatment of mild depression does not lead to improved outcomes, then this greater … The comments did not lead to significant changes but were helpful in identifying additional factors of

480. Instrumental Variable Methods in Comparative Safety and Effectiveness Research | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/instrumental-variable-methods/research
     May 14, 2010 - Small violations of IV assumptions can lead to tremendous inconsistency in the IV estimator when the … Variation in formularies, hospital capacity, and prescription drug benefit plan structure can also lead … However, this can lead to bias if the IV is associated with the actual dose within a dose category. 38