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441. Choice-Of-Mean White-Paper (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
     April 01, 2015 - A significant difference in baseline scores did not necessarily lead to discrepancy in conclusion. … indicated that using the change score versus the followup score to estimate mean difference could lead … there is baseline imbalance, using the change versus followup score to estimate mean difference would lead … Nevertheless, significant baseline difference does not necessarily lead to discrepancy in conclusions … the analysis.30 In summary, using the change score versus the followup score to estimate MD could lead

442. Cerebral-Palsy-Feeding Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cerebral-palsy-feeding_executive.pdf
     March 01, 2013 - Difficulties and Interventions Individuals with CP frequently have feeding and swallowing problems that may lead … reflux (GER), particularly those with severe CP, are also at risk for recurrent aspiration, which can lead … Clearly, surgical interventions can lead to increased weight gain; the degree to which harms outweigh … this review will help policymakers and researchers understand what types of studies are essential to lead … reflux that occurs more than twice a week or causes symptoms is considered GERD, and it can eventually lead

443. Appendix K Rapid Evidence Review Treatments for Clostridium difficile Colitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/clinical-pathway-methods-report-appendix-k.pdf
     February 01, 2018 - (ECRI Institute) Lead analyst: J. Jane S. Jue, M.D., M.Sc. … ileostomy with colonic lavage followed by antegrade vancomycin flushes is an alternative approach that may lead … ileostomy with colonic lavage followed by antegrade vancomycin flushes is an alternative approach that may lead … In a few people C. difficile infection can lead to pseudomembranous colitis, sepsis, toxic megacolon

444. Alcohol-Misuse-Drug-Therapy Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
     January 27, 2012 - 1 Comparative Effectiveness Review Number 134 Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings Executive Summary Background Alcohol misuse, or unhealthful alcohol use, which includes the full spectrum from drinking above recommended limits (i.e., risky/hazardous drinking) to alcoho…

445. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - Slowing disease progression could lead to improved quality of life and reduced costs. … Slowed disease progression could lead to improved patient quality of life and reduced costs. … COPD exacerbations can lead to significant declines in lung function and progression towards respiratory

446. Disposition of Comments for Migraine in Adults: Preventive Pharmacologic Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
     April 18, 2013 - Reviewer 3 ES: Treatment safety is defined by the rates of adverse effects that lead to treatment … follows: “Treatment safety is defined by the total rates of adverse effects and adverse effects that lead

447. Disposition of Comments Report for Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
     September 10, 2014 - surgeons that if a lesion is seen on multiple modalities, the choice of X to guide the biopsy will lead … However, we found that they lead to “busy” and hard to read plots and for this reason we did not retain … Because over-diagnosis is the end result of lead time (due to screening) and competing risks (specifically … Because over diagnosis is the end result of lead time (due to screening) and competing risk (specifically … There are failures in the system that lead to inadequate excision of non-palpable lesions, and that

448. Continuous-Outcomes-Quantitative-Synthesis Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
     March 01, 2011 - Simply omitting trials with data that are MNAR will lead to biased results. 26 Missing Summary … We recommend that studies missing only SDs should not be excluded, as this could lead to a biased combined … Studies missing only SDs should not be excluded as this may lead to a biased combined estimate when … Direct substitution using the largest SD is the simplest method and the most likely to lead to a conservative … However, if one is comfortable with one of the more complex methods, using it may lead to a more accurate

449. Technical Brief – Wheeled Mobility (Wheelchair) Service Delivery | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/wheelchair-service/research-protocol
     July 01, 2010 - Current Page Topic Timeline May. 28, 2010 Topic Initiated Jul. 1, 2010 Research Protocol Jan. 17, 2012 Technical Brief Jun. 1, 2014 Disposition of Comments Report Technical Brief – Wheeled Mobility (Wheelchair) Service Delivery Research Protocol Archived July 1, 2010 Download Main Document PDF 601.4 KB …

450. Comparative Effectiveness of Angiotensin Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), and Direct Renin Inhibitors for Treating Essential Hypertension – An Update of the 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/ace-inhibitor-arb-update/research-protocol
     May 07, 2010 - Current Page Topic Timeline Mar. 16, 2010 Topic Initiated May. 7, 2010 Research Protocol Jun. 13, 2011 Systematic Review Oct. 7, 2011 Disposition of Comments Report Mar. 28, 2016 Surveillance Report Comparative Effectiveness of Angiotensin Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARB…

451. PowerPoint Presentation
     effectivehealthcare.ahrq.gov/sites/default/files/facilitation-webcast-slides.pptx
     June 13, 2013 - the process for training facilitators. 22 Structured Facilitator Guide Activity, objective, time, lead

452. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
     June 01, 2011 - Layout 1 Background Almost 75 million American adults— approximately one-third—have hypertension. The prevalence of hypertension increases with advancing age such that more than half of people 55 to 74 years old and approximately three-fourths of those age 75 years and older are affected. In addition to being the pr…

453. Rheumatoid-Arthritis-Medicine Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
     April 01, 2012 - 1 Comparative Effectiveness Review Number 55 Drug Therapy for Rheumatoid Arthritis in Adults: An Update Executive Summary Background Rheumatoid arthritis (RA), which affects 1.3 million adult Americans, is an autoimmune disease that involves inflammation of the synovium (a thin layer of tissue lining a joint …

454. Use of Telehealth During the COVID-19 Era (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/telehealth-covid-19-disposition-comments.pdf
     January 03, 2023 - for CF, the Cystic Fibrosis Foundation’s mission is to give all people with CF the opportunity to lead

455. Hypertension-Pulmonary-Arterial Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
     April 01, 2013 - later stages of PH, RV function deteriorates, which can lessen the degree of sPAP elevation and lead … TAPSE 4 (251) 0.94 (0.82 to 1.08) SOE = Insufficient Inconsistent results between studies lead to uncertainty … placebo SOE = Insufficient (6 studies, 838 patients) Inconclusive benefit (few studies, few deaths lead … placebo SOE = Insufficient (4 studies, 1,011 patients) Inconclusive benefit (few studies, few deaths lead … monotherapy SOE = Insufficient (3 studies, 566 patients) Inconclusive benefit (few studies, few deaths lead

456. Fleisher (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/fleisher.pdf
     January 01, 2010 - o What does it take to integrate these technologies, and does it lead to a more empowered patient?

457. preoperative-testing-protocol-130514 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/preoperative-testing_research-protocol.pdf
     May 14, 2013 - • Aberrant test results may lead to cascade testing (either appropriate if the test result signals …  sickle  cell)   o Urinalysis   o Pregnancy  tests   o Chest  radiography   o 12-­‐lead

458. Routine Preoperative Testing: Comparative Effectiveness Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/preoperative-testing/research-protocol
     May 14, 2013 - Aberrant test results may lead to cascade testing (either appropriate if the test result signals a real … Hemoglobinopathy tests (e.g., sickle cell) Urinalysis Pregnancy tests Chest radiography 12-lead

459. Comparative Effectiveness of Non-Invasive Diagnostic Tests for Breast Abnormalities – An Update of a 2006 Report | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/breast-abnormalities-tests-update/research-protocol
     June 28, 2010 - The comments received on the Key Questions did not lead to revisions of the Key Questions. … Although we recognize that excluding non-English studies could lead to bias in some situations, we believe

460. Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/copd/protocol
     October 10, 2018 - Current Page Topic Timeline Jan. 26, 2018 Topic Initiated Oct. 10, 2018 Research Protocol Oct. 11, 2019 Systematic Review Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review Research Protocol October 10, 2018 Download Main Document PDF 302.7 KB …