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401. Physical Therapy for Knee Pain Secondary to Osteoarthritis Disposition of Comment Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
     November 06, 2012 - Also recommend changing the presentation of results of KQ1 in the summary (pg 50) so that the authors lead … Don’t bury your lead. … This conclusion again minimizes the effectiveness of some treatments, especially exercise and will lead … The discussion of these points and the recommendation for future research that lead from them can be … The variety of methods and results reviewed under KQ2 that prevented firm conclusions should lead the

402. Ventricular Arrhythmias and Cerebrovascular Events in the Elderly Using Conventional and Atypical Antipsychotic Medications | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/antipsychotic-medicine-cardiovascular-elderly/research
     March 18, 2009 - Hypoperfusion has been shown to lead to microinfarcts in dementia patients and investigators have proposed … for any improvements in the prevention of cardiac or cerebrovascular events, which could otherwise lead

403. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
     March 10, 2010 - Methods It is not clear how information in Table 3 would lead to pre-planned 7440 meta-analysis. … Our involvement with requests for data for the review began in May 2008 when lead authors of some manuscripts … Timelines: Letters from Chalmers to lead authors: April 16 to May 2, 2008 Forwarded to Merck by lead … Events post randomization affecting analysis may lead to post randomization imbalance

404. Making Sure That Evidence Is Understood and Used (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-making-sure-evidence-understood.pdf
     July 01, 2020 - AHRQ is the lead Federal agency within the U.S.

405. Surveillance Report: Masks for Prevention of COVID-19 in Community and Healthcare Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-surveillance-report.pdf
     July 17, 2020 - When studies lead to a change in conclusions, the report will be updated.

406. Disposition of Comments_Comparative Effectiveness Review No. 269_Respectful Maternity Care: Dissemination and Implementation of Perinatal Safety Culture To Improve Equitable Maternal Healthcare Delivery and Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-269-respectful-maternity-care-disposition-comments.pdf
     January 02, 2024 - Disrespectful care can lead to delayed or missed diagnoses, delayed referral to specialized care, and … ) General (cont’d) (comment above) • Discussion: note the need to recognize conditions that lead … Discussion 4.4: paragraph beginning “There is growing awareness that obstetric emergencies can lead … particular the paragraph beginning “There is growing awareness that obstetric emergencies can lead … recognizing ongoing need to identify and mitigate health systems factors that create conditions that lead

407. S77 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
     October 01, 2007 - Because of the effect of the annual out-of-pocket maximum at the VA, this scenario would lead to 20 veterans

408. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
     December 09, 2009 - Each abstract is being reviewed by the Scientific Director, Content Lead, Content Experts, Associate

409. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - of the brain. 17 Physicians often perform the device implantation in two separate procedures: lead

410. Agenda: Impact of Healthcare Algorithms on Racial and Ethnic Disparities (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/healthcare-algorithms-agenda-for-March-23.pdf
     March 13, 2023 - tools should be developed, validated, implemented, and updated to avoid introducing bias that could lead

411. Disposition of Comments for Evidence Report #208 Part 5 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_disposition-comments.pdf
     July 26, 2012 - To be sure, the argument that making performance information available to the public will lead to a … Transparency can lead to informed decision-making, which may or may not impact “quality of care”. … consumer decisions are a product of being more engaged in their health or healthcare, but don’t always lead … presume simple causality – “Does public reporting RESULT IN improvements,” “Does public reporting LEAD … for e.g. that public reporting plus more targeted TA to low performers, or other tactic, might then lead

412. Topic Brief: Screening and Treating Non-Alcoholic Fatty Liver Disease (pdf file)
     effectivehealthcare.ahrq.gov/system/files/docs/na_liver_disease_topic_brief_topic_brief.pdf
     October 30, 2020 - NASH is made when there is evidence of inflammation that can cause liver damage which, in turn, can lead … 22function+test%22+OR+imaging+OR+screen+OR+%22steatosis+score%22+OR+ultrasound&titles=&outc=&spons=&lead

413. CER 215 Executive Summary: Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cer-215-depression-older-adults-executive-summary.pdf
     March 01, 2019 - (SNRIs) (duloxetine and venlafaxine) cause adverse events more often than placebo and most likely lead … fluoxetine) most likely cause adverse events at a similar frequency to placebo therapy but still may lead

414. CER 215 Executive Summary: Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
     March 01, 2019 - inhibitors (SNRIs) (duloxetine and venlafaxine) cause adverse events more often than placebo and most likely lead … fluoxetine) most likely cause adverse events at a similar frequency to placebo therapy but still may lead

415. Strategies to De-escalate Aggressive Behavior in Psychiatric Patients (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_disposition-comments.pdf
     July 14, 2016 - At many places in the document, the unique aspects of this study are not highlighted, which could lead … needs to be specific to the population being treated otherwise it might not target the symptoms that lead … areas of study include the following: • Does engaging patients in their own treatment decision lead

416. Preoperative-Testing Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/preoperative-testing_executive.pdf
     January 01, 2014 - .2 As all routine testing does, preoperative testing will find some abnormal test results that will lead … The variation in the characteristics of patients undergoing surgery may lead to considerable differences … if no further treatment or evaluation was truly needed), and cascade testing (where abnormal tests lead … Rather than leading to more or less testing, it can lead to more appropriate testing, since the tendency

417. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fetal-surgery_disposition-comments.pdf
     July 05, 2011 - Peer Reviewer #7 Results the description of the balloon may lead to confusion: itIS a specialized … question the proposal that a “neutral but knowledgeable” clinician, “preferably not the surgeon” lead

418. Template for Reports Developed (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-updates_methods.pdf
     July 01, 2011 - Lack of attention to updating may lead to outdated and sometimes misleading conclusions that compromise … to be regularly updated as new evidence is produced. 1,2 The lack of attention to updating may lead … These problems could lead to a waste of resources, provision of redundant or ineffective health care

419. Hi Les, (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
     January 01, 2009 - high-grade cervical abnormalities.7,8 Based on this evidence, we conclude that LBC will not directly lead … are the magnitude of the increase in sensitivity; the extent to which true positive test findings lead … For example, full-body computed tomography (CT) might lead to reduced morbidity and mortality due to

420. Effectiveness of Practice-based Interventions Addressing Concomitant Mental Health and Chronic Medical Conditions in the Primary Care Setting | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/depression-chronic-conditions-interventions/research-protocol
     September 21, 2011 - Current Page Topic Timeline Mar. 18, 2011 Topic Initiated Sep. 21, 2011 Research Protocol Aug. 13, 2012 Systematic Review Nov. 20, 2012 Disposition of Comments Report Effectiveness of Practice-based Interventions Addressing Concomitant Mental Health and Chronic Medical Conditions in the Primary Care Setting Researc…