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401. Dispostion of Comments Report for Screening for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
     November 27, 2012 - This is not a sufficient reason for testing and actually can lead to labeling and harms. … The page number alone is daunting and will lead most would-be readers to forget about it. … liver disease; even compensated cirrhotic patients often do not have signs or symptoms that would lead … This confusion has lead to inaction and the loss of life.

402. McCormack-notes-151008 copy - Teresa (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/mccormack-presentation.pdf
     May 29, 2025 - McCormack-notes-151008 copy - Teresa My talk today is about engaging patients with  low health  literacy. 1 Health literacy is a key factor in securing access to healthcare services. So in my talk today, I’ll talk a little bit about health literacy and what it is, how we measure health literacy and the sta…

403. Slide 1 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/module_iii2.ppt
     May 29, 2025 - Slide 1 Engaging Stakeholders in the Effective Health Care Program Information and tools for researchers and investigators Numeric

404. Disposition of Comments for Technical Brief 21, Management Strategies To Reduce Psychiatric Readmissions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/psychiatric-readmissions_disposition-comments.pdf
     May 21, 2015 - There is no evidence cited for the statement "readmission can lead providers and patient to feel demoralized … The questions were fine, but did the structuring of the discussion around those questions lead to more … a paradoxical increase in readmissions, but allowing symptoms to be controlled more rapidly could lead … It can also lead some individuals to leave the jurisdiction to avoid the constraints of outpatient … Interventions could lead to a statistically and clinically significant improvement for large numbers

405. Development of Harmonized Outcome Measures for Use in Patient Registries and Clinical Practice: Methods and Lessons Learned (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-standardized-library.pdf
     February 01, 2019 - Development of Harmonized Outcome Measures for Use in Patient Registries and Clinical Practice: Methods and Lessons Learned Final Report Development of Harmonized Outcome Measures for Use in Patient Registries and Clinical Practice: Methods and Lessons Learned Final Report …

406. Transparency of Reporting Requirements: Effectiveness of Treatments Options for the Prevention of Complications and Treatment of Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research-protocol.pdf
     September 01, 2016 - systematic reviews, because of reporting bias such as publication bias and outcome reporting bias, may lead

407. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain_executive.pdf
     January 01, 2012 - anterior abdominal wall, lower back, or buttocks, and that is serious enough to cause disability or lead … Treatment choices include surgical or nonsurgical approaches and may lead to outcomes that include changes

408. Supplemental Project To Assess the Transparency of Reporting for Strategies To Improve Mental Health Care for Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-mental-health_research.pdf
     January 01, 2017 - Disseminating Information on Study Outcomes and Processes (KQ 4) As noted in Table 2, three investigators (lead … responded to us but was unable to provide us with information because the principal investigator (lead

409. Gout-managment-protocol-141103 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol.pdf
     November 03, 2014 - episodes if untreated, under-treated or improperly treated, may increase in frequency and duration and lead … disagreements regarding inclusion at the full-text stage will be reconciled, with the input of the project lead

410. The Effect of Dietary Digestible Carbohydrate Intake on Risk of Cardiovascular Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
     January 01, 2023 - The Effect of Dietary Digestible Carbohydrate Intake on Risk of Cardiovascular Disease Evidence-based Practice Center Systematic Review Protocol Project Title: The Effect of Dietary Digestible Carbohydrate Intake on Risk of Cardiovascular Disease I. Background and Objectives for the Systematic Review Des…

411. Disposition of Comments for Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
     April 22, 2013 - isn't anything about how the categories of interventions were chosen or how the framework would lead … In general, the narrow framing of the inclusion population may lead to the potential for "false negatives … drug such as olanzapine or clozapine that has a high weight gain risk would seem much more likely to lead … Switching rapidly with no cross-taper would seem more likely to lead to symptom relapse than switching

412. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-postpartum-screening_research-protocol.pdf
     May 01, 2013 - criteria for major depression improves outcomes.3,4,23 If a diagnosis of “minor depression” does not lead … As noted above, if treatment of mild depression does not lead to improved outcomes, then this greater … The comments did not lead to significant changes but were helpful in identifying additional factors

413. Comparative Effectiveness Research Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disabilities-quality-improvement-outcomes_disposition-comments.pdf
     October 15, 2012 - These multiple broad conceptual frameworks then abruptly lead to specific key questions to be addressed … While such studies may lead eventually to quality improvement, we did not include them here as they

414. Ptsd-Adults-Trauma-Interventions Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
     November 08, 2012 - the APA guidelines report that there is only minimal evidence that early supportive care alone can lead … Team Disclosures With the exception of the following, the team had no interests to disclosure: • Lead

415. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - This would inevitably lead to an increase in screening, an increase in Barrett’s [esophagus] being … Bacterial overgrowth in the small intestine may lead to increased gas production, diarrhea, and weight

416. Disposition of Comments for Technical Brief 23 Genetic Testing (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/genetic-testing-developmental-disabilities_disposition-comments.pdf
     June 30, 2015 - meet a semantically precise definition of the word cure, the result is that the child can ultimately lead … On page 5 of the report Key Question 1 is stated as, “Does using a genetic test lead to improved health … It feels like all testing has been grouped together in aggregate, and that might lead to the interpretation … related to diagnostic yield and ends with the statement, “Improved diagnostic yield may not necessarily lead … pulling the conclusions together using bullets or the Guiding Questions would be very helpful and would lead

417. Comparative Effectiveness Review No. 258_Diagnostic Errors in the Emergency Department: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diagnostic-error-executive-summary.pdf
     August 01, 2023 - remembered that not all diagnostic errors are preventable and attempting to prevent some errors may lead

418. Adverse Events Associated with COVID-19 Pharmaceutical Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments.pdf
     December 23, 2023 - Adverse Events Associated with COVID-19 Pharmaceutical Treatments Evidence-based Practice Center Rapid Review Protocol Project Title: Adverse Events Associated with COVID-19 Pharmaceutical Treatments I. Background and Objectives for the Systematic Review The Public Readiness and Emergency Preparedness A…

419. Data Points 13: Use of Preoperative Breast MRI among older women with ductal carcinoma in situ and locally invasive breast cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-mri-utilization_research.pdf
     August 01, 2012 - underestimate the extent of DCIS and invasive cancer.7 Magnetic resonance imaging (MRI) findings may lead

420. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
     May 19, 2010 - Evidence Report on the Source: www.effectivehealthcare.ahrq.gov Published Online: May 19, 2010 Evidence-based Practice Center Systematic Review Protocol Project Title: Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics – Update I. Background and Objectives for the Sys…