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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
    December 06, 2010 - are reviewed for completeness and accuracy by a second senior member of the team, most often the lead
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
    May 08, 2013 - surprised that the extremely well done and large PRESSURE study published in 2006 in BMJ (Jane Nixon lead … How could a risk assessment tool lead to better outcomes other than through the more appropriate use … risk assessment scores (blinding might be difficult for ethical reasons), which would be expected to lead … surprised that the extremely well done and large PRESSURE study published in 2006 in BMJ (Jane Nixon lead … focus on the three sub-groups contradicts, complicates and confounds the main question and so has lead
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
    March 01, 2025 - Executive Summary_Systematic Review: Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition Systematic Review Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition Execu…
  4. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - #05 DEPRESSION AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 05: Depression and Other Mental Health Disorders Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road Rockville, MD…
  5. effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
    October 01, 2010 - times as many equally sized studies to achieve the same power as direct comparisons, and frequently lead … estimates are usually similar to estimates using the above methods, though choice of vague priors could lead … relation to these decisions and assumptions. 60 Results are robust if decisions and assumptions only lead
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topics_methods.pdf
    January 01, 2010 - Ideal EHC research topics are those that can clearly lead to evidence-based practice and policies … technology. 2 An area of action where better evidence of cost effectiveness would be expected to lead
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
    October 01, 2010 - times as many equally sized studies to achieve the same power as direct comparisons, and frequently lead … estimates are usually similar to estimates using the above methods, though choice of vague priors could lead … relation to these decisions and assumptions. 60 Results are robust if decisions and assumptions only lead
  8. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
    March 01, 2012 - Comments: Overall, experts commenting on this topic believe that bariatric surgery has potential to lead … also envisioned that early versions of the artificial pancreas would be expensive and most likely lead … m 2 Overall, experts commenting on this topic believe that bariatric surgery has potential to lead
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
    November 01, 2012 - A comprehensive review of the effectiveness and harms of treatments for RLS could lead to improved … sleep disruption may lead to poor daytime functioning, anxiety, and depression. … Recommendations Augmentation • Augmentation is a significant harm with dopaminergic therapy and can lead … to treatment discontinuation; yet, little is known about patient characteristics that may lead to
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
    November 29, 2023 - protein to help repair and maintain itself,22,23 and failure to properly stimulate muscle protein can lead … used DerSimonian-Laird approach which may result in overly narrow confidence intervals that can lead
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
    November 28, 2023 - If protein intake is inadequate, it can lead to detrimental health effects.8 Notably, the 2020–2025 … commonly used DerSimonian-Laird approach which may result in overly narrow confidence intervals and can lead
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
    July 01, 2010 - The comments received on the Key Questions did not lead to revisions of the Key Questions. … Although we recognize that excluding non-English studies could lead to bias in some situations, we believe
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-information-exchange_research-protocol.pdf
    April 20, 2015 - The comments did not lead to significant changes but were helpful in identifying additional factors
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-mortality-elderly_research.pdf
    March 01, 2009 - also supports the contention that conventional APM may be associated with cardiovascular events that lead … for any improvements in the prevention of cardiac or cerebrovascular events, which could otherwise lead
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/machine-learning-quality_research.pdf
    September 01, 2012 - higher in intervention than in control practices; results for screening for tuberculosis (54% v 32%), lead … Recent closures of rural hospitals have lead to difficulties with access to surgical services. … correlational study, not intervention evaluation) Robotically assisted left ventricular epicardial lead … To provide a minimally invasive option for these patients with LV lead failures, we developed a technique … of endoscopic, epicardial LV lead implantation with the use of the da Vinci robotic system.
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
    January 01, 2015 - Adoption of idelalisib-containing regimens for treating recurrent/refractory CLL, SLL, and FL would lead … They could also lead to price competition, which will reduce the extra costs associated with all of … Widespread use of Evzio could lead to as many as 591 lives saved nationally per 6-month period.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-chemotherapy-dental.pdf
    July 01, 2023 - a study (either at the abstract or full-text stage of review), then the study was flagged for the lead … can last as long as a year.16 Impaired immunity increases the risk of serious infections that can lead … mucositis,25 although one study using a large national database53 found that plaque removal also can lead
  18. McCullough (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/mccullough.pdf
    January 01, 2011 - McCullough Slide  1: An Ethical Framework for Supporting  Shared Decision Making  When Clinical Evidence is Low Laurence B. McCullough, Ph.D. Dalton Tomlin Chair in Medical Ethics and Health Policy Associate Director for Education Center for Medical Ethics and …
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
    October 07, 2011 - In other words, inclusion strategies must be aligned with and take their lead from what a reasonable … However, there may be other key pharmacological differences between the different classes that may lead
  20. effectivehealthcare.ahrq.gov/sites/default/files/08_functional_limitations_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - subsequent damage to the spinal cord and brain interfere with a variety of functions, which can eventually lead … Inspiration and Ipsen have jointly chosen an investment banker to lead the sale process, and Inspiration … clinical perspective indicated that increased understanding of this therapy’s mechanism of action “could lead … migraine, inpatient admissions, and provides an alternative to opioids or barbiturates (which frequently lead

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