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361. Despite steadily increasing health care expenditures in the United States, improved health outcomes and quality remain elusive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-interventions-comparing_methods.pdf
     November 01, 2008 - To maintain the objectivity of a review, lead authors on the reports are barred from having any significant

362. Diagnosis and Management of Gout: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
     January 01, 2017 - include gastrointestinal perforations, ulcers, and increased risk of heart attack or stroke that can lead

363. Despite steadily increasing health care expenditures in the United States, improved health outcomes and quality remain elusive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_slutsky_comparing_medical_interventions.pdf
     November 01, 2008 - To maintain the objectivity of a review, lead authors on the reports are barred from having any significant

364. Dementia-Nursing-Home-Characteristics Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_executive.pdf
     October 01, 2012 - With Dementia Executive Summary Background Dementia is a group of neurological conditions that lead … community by family members; however, increasing care needs in later stages of the illness often lead … mobility, and frequent infections so that, unless some other illness is fatal sooner, dementia will lead

365. Traumatic-Brain-Injury-Rehabilitation Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
     June 01, 2012 - intensive medical care, and 40 percent of those hospitalized with nonfatal TBIs sustain impairments that lead … Outcomes selected for review can also lead to inconsistent findings across reviews. … Evidence suggested that the ICRP may lead to earlier productivity than standard rehabilitation (low

366. Cad-Women-Diagnosis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
     June 01, 2012 - Will knowing the coronary anatomy (nonobstructive or obstructive) in symptomatic patients lead to better … This is important because a positive NIT result could lead to further testing to establish the diagnosis … of CAD as well as lead to more attention to secondary prevention for CAD.

367. Methods White Paper: Improving the Utility of Evidence Synthesis for Decision Makers in the Face of Insufficient Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/improving-utility-evidence-synthesis-white-paper.pdf
     April 01, 2021 - reviewers may discover that flaws in the conduct of the study or overall imprecision or inconsistency lead … Review authors can also consider qualifying the term “insufficient” by stating the main reason that lead … Communicating uncertainty can lead to less decision satisfaction: a necessary cost of involving patients … Does memantadine in addition to buprenorphine lead to higher rates of abstinence and/or less use.

368. Screening and Diagnosing Gestational Diabetes Mellitus Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_disposition-comments.pdf
     January 01, 2020 - Any change in diagnostic criteria will most probably lead to change in management/BG targets of women … The condition can lead to short- and long-term health problems for the mother and fetus including immediate

369. Han (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/han.pdf
     December 26, 2012 - Han Slide 1: Conceptual, methodological, and ethical problems  in communicating   uncertainty  in clinical  evidence Paul Han, MD, MA, MPH Center for Outcomes Research and Evaluation Maine Medical  Center Slide 2: Communicating  uncertainty in clinical …

370. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
     July 01, 2009 - of inconsistency is the chief concern for grading strength of evidence in this domain, and it would lead … Imprecise data may also lead to a grade of insufficient, specifically when the confidence interval is … directness, and precision may reveal strengths or weaknesses with the entire body of evidence and lead

371. Research White Paper Biorepositories Addendum Registries For Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/biorepositories-registries-guide-3rd-ed-addendum-white-paper.pdf
     February 01, 2018 - (Lead) University of Texas Southwestern Medical Center Jennifer Christian, Pharm.D., M.P.H., Ph.D. … Each of these situations will lead to different procedures for procurement. … de-identified, aggregated databases.48 The unintended release or disclosure of personal information can lead … that conflict with their fundamental values.63 Other commentators suggest that blanket consent may lead

372. Mental-Illness-Adults-Prisons Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-adults-prisons_executive.pdf
     August 01, 2013 - This is an especially vulnerable population because “jails and prisons have cultures that often lead … “Intermediate outcomes,” which may lead to improved patient-oriented outcomes, include adherence to … Again, this conclusion is based on only two trials, and whether increased service use will lead to

373. Colorectal-Surgery-Preparation Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
     March 26, 2013 - tests are often referred to as tests for publication bias; reasons other than publication bias can lead … following team members will be involved: • The EPC Director • The EPC Codirector • One Project Lead … • One Co-Project Lead/Research Associate • One Local Clinical Expert • One Project Manager • One

374. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1412.pdf
     October 01, 2015 - Blocking these receptors is thought to inhibit the cycles of inflammation and lung repair that lead … These receptors are thought to be involved in cycles of inflammation and lung repair that lead to lung … Additionally, some experts thought that an increased pool of donor lungs would lead to more lung transplants

375. new disposition of comments insulin analogues -- jda revs.xls (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/insulin-analogues-disposition-081229.pdf
     September 01, 2008 - That might inadvertently lead some physicians to use insulin less often, when it is likely that physicians … However, that doent lead to the next step, that "studies should be planned". … So while these are interesting and legitimate questions, the present dstudy does not lead to the conclusion … THERE IS A REAL DANGER THAT THIS CONCLUSION WILL BE MISINTERPRETED BY SOME PARTIES, TO LEAD TO LONGER

376. Methods Future Research Needs Number 8: Framework for Considering Study Designs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-framework_research.pdf
     March 01, 2012 - Centers (EPCs); it represents initial guidance, as additional experience with future research needs may lead … for producing a valid result: Selection bias and group differences in patient characteristics may lead

377. Protocol: Imaging for Pretreatment Staging of Small Cell Lung Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
     December 08, 2014 - False positive results can also occur due to other non-malignant conditions that lead to increased bone … English language: Although we recognize that in some situations exclusion of non-English studies could lead

378. An analytical framework for quantifying components of variability in prescriber decisions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
     April 01, 2010 - Small violations of IV assumptions can lead to tremendous inconsistency in the IV estimator when the … Variation in formularies, hospital capacity, and prescription drug benefit plan structure can also lead … However, this can lead to bias if the IV is associated with the actual dose within a dose category.

379. Wheelchair-Service Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-service_research-protocol.pdf
     July 01, 2010 - Source: www.effectivehealthcare.ahrq.gov Published Online: July 01, 2010 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Technical Brief – Wheeled Mobility (Wheelchair) Service Delivery I. Background and Objectives for the Technical Brief Wheeled mobility or wheelchair use is …

380. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
     May 07, 2010 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: May 07, 2010 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Angiotensin Converting Enzyme Inhibitors (ACEIs) …