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341. Musculoskeletal-Complaints-Tests-Children Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_executive.pdf
     March 01, 2012 - observed for almost all the test-disease combinations; however, the design of case-control studies may lead … .52-54 The selective inclusion of cases with established disease (i.e., JIA or pSLE) is likely to lead … inclusion of healthy controls is expected to decrease the likelihood of false positive test results and lead

342. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
     December 06, 2010 - of the synovium (a thin layer of tissue lining a joint space) and progressive erosion of bone that lead … will be reviewed for completeness and accuracy by a second senior member of the team, most often the lead

343. PCA3 Testing for the Diagnosis and Management of Prostate Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/prostate-cancer-test/research-protocol
     October 14, 2011 - These programs are based on the premise that PSA testing can lead to early detection of prostate cancer … However, testing total PSA levels to decide which patients should undergo a biopsy has been found to lead … When total PSA testing identifies patients with cancer-positive biopsies, it can again lead to overtreatment

344. Disposition of Comments for Venous Thromboembolism Prophylaxis in Orthopedic Surgery (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
     March 01, 2012 - surgery patients at a much higher rate than general surgery or other medical patients, and it can lead … Cardio-vascular Therapeutic Area Lead Ortho-McNeil Janssen Scientific Affairs Payal Desai, … Cardio-vascular Therapeutic Area Lead Ortho-McNeil Janssen Scientific Affairs Payal Desai, … Cardio-vascular Therapeutic Area Lead Ortho-McNeil Janssen Scientific Affairs Payal Desai, … Cardio-vascular Therapeutic Area Lead Ortho-McNeil Janssen Scientific Affairs Payal Desai,

345. Amended Protocol: Maternal and Childhood Outcomes Associated with the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/wic-outcomes-nutrition-protocol-amended.pdf
     October 01, 2020 - education, breastfeeding support and support of and referral to other services, which are thought to lead … specific race/ethnic groups, or who are non-English speaking; c) explorations of why/how services lead … nutrition education, breastfeeding support, and referral services) through which WIC participation may lead

346. Evidence Summary_Comparative Effectiveness Review No. 255: Transitions of Care From Pediatric to Adult Services for Children With Special Healthcare Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-255-transitions-care-pediatric-to-adult-services-evidence-summary.pdf
     May 01, 2022 - transitioned from pediatric to adult healthcare providers.3 Such transitions are often difficult and can lead

347. Pneumonia-Antibiotic-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
     November 01, 2014 - Furthermore, measuring PK/PD only in the serum may lead to suboptimal antibiotic concentrations at the … In such cases, the antibiotic may not eradicate resistant organisms; this problem may in turn lead … recommendations are based largely on PK/PD studies in healthy volunteers, the recommendations may lead

348. Topic 0613 Tympanostomy Tubes NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
     November 03, 2014 - Topic 0613 Tympanostomy Tubes NSD FINAL Tympanostomy Tubes in Children Nomination Summary Document Results of Topic Selection Process & Next Steps § Th…

349. What is the comparative effectiveness of genetic and other diagnostic tests to identify and treat intellectual and developmental disabilities caused by genetic mutations in post-natal to early childhood populations? | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-of-genetic-and-other-diagnostic-tests-to-identify-and-treat-intellectual-and-developmental-disabilities-caused-by-genetic-mutations-in-post-natal-to-early-childhood-populations
     October 26, 2012 - Home » Get Involved » Nominated Topics » Topic Suggestion Description Topic Suggestion Description Date submitted: October 26, 2012 Download Topic Suggestion Disposition [PDF · 1.2 MB] Briefly describe a specific question, or set of related questions, about a health …

350. Comparative Effectiveness of Drug Therapy for Psoriatic Arthritis in Adults – An Update to the 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/arthritis-psoriatric/research-protocol
     December 06, 2010 - abstractions are reviewed for completeness and accuracy by a second senior member of the team, most often the lead

351. Traumatic Brain Injury and Depression | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/depression-brain-injury/research-protocol
     December 09, 2009 - Each abstract is being reviewed by the Scientific Director, Content Lead, Content Experts, Associate

352. Mobile Health Technology for Diabetes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-mobile-devices_research-protocol.pdf
     July 12, 2017 - tools could help patients adhere to diet, exercise, and medication management plans, which could lead

353. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - This may lead to different outcomes among treatment centers. … However, the mechanism by which these cells lead to cartilage regeneration is unclear.1 MSCs may differentiate … conservative treatment are considerable, and the reported adverse events appear minimal, which could lead … the lower costs and greater symptom relief of PRP over hyaluronic acid injections will eventually lead

354. Ch 6-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
     October 30, 2012 - 76 Developing an Observational CER Protocol: A User’s Guide composite endpoints, such as MACE, can lead … Not only can varying definitions of composite endpoints such as MACE lead to substantially different … For any medical condition, one should first determine the source of reporting or detection that may lead … to the patient’s overall health status.41 Floor and Ceiling Effects Poor content validity can also lead … Failure to account for missing PRO data that are related to poor health or death will lead to an overestimate

355. Osteoporosis-Vibration-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_research-protocol.pdf
     January 01, 2020 - 1 Source: www.effectivehealthcare.ahrq.gov Published Online: December 9, 2010 Evidence-based Practice Center Technical Brief Project Title: Whole-Body Vibration Therapy for Osteoporosis I. Background and objectives Osteoporosis is a disease of the skeletal system characterized by low bone mass and de…

356. Disposition of Comments for CER 183 Tonsillectomy for OSDB (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
     January 17, 2017 - Response Peer reviewer #1 Results Another point that is not well discussed is whether T, A or T+A lead … Does a cold versus hot technique lead to less PTH? b. … Does partial versus total tonsillectomy lead to less PTH?

357. Research Protocol (Amended): Treatment of Acute Pain--An Evidence Map (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-protocol-amended.pdf
     June 10, 2018 - Effective treatment of acute pain can minimize the sensitization of pain pathways and tissue damage that lead … The subjective nature of self-report and provider interpretation can lead to a wide range of treatment

358. Technical Brief: Whole Body Vibration Therapy for Osteoporosis | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/osteoporosis-vibration-therapy/research-protocol
     December 09, 2010 - Current Page Topic Timeline Dec. 8, 2010 Topic Initiated Dec. 9, 2010 Research Protocol Nov. 15, 2011 Technical Brief Dec. 3, 2012 Disposition of Comments Report Technical Brief: Whole Body Vibration Therapy for Osteoporosis Research Protocol Archived December 9, 2010 Download Main Document PDF 681.9 KB …

359. Methods Guide for Medical Test Reviews Chapter 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-topics_methods.pdf
     July 01, 2012 - Methods Guide for Medical Test Reviews Chapter 2 2-1 Chapter 2 Developing the Topic and Structuring Systematic Reviews of Medical Tests: Utility of PICOTS, Analytic Frameworks, Decision Trees, and Other Frameworks David Samson, M.S., Blue Cross and Blue Shield Association Karen M. Schoelles M.D., S.…

360. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - #06 Developmental Delays ADHD, and Autism AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 06: Developmental Delays, ADHD, and Autism Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither…