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321. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
     March 28, 2019 - These issues lead to questions about the ratings of low risk of bias for the individual studies and … , in turn, lead to questions about the appropriateness of the strength of evidence ratings. … Attempts to search for only a subgroup would lead to a narrower search and potentially missing papers … Attempts to search for only a subgroup would lead to a narrower search and potentially missing papers … Attempts to search for only a subgroup would lead to a narrower search and potentially missing papers

322. Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Testing for the Evaluation of Musculoskeletal Complaints in Pediatric Populations | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/musculoskeletal-complaints-tests-children/research-protocol
     September 29, 2010 - follow-up to a negative RF test when clinical signs, such as symmetrical joint pain and inflammation, lead … effective treatment, JIA can progress and cause damage to cartilage, bone and soft tissues, and may lead … diagnosis has become more common 20 and rapid introduction of aggressive immunosuppressive treatment may lead

323. Nephropathy-Contrast-Induced Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive.pdf
     October 01, 2015 - Clinicians often worry about the possibility that intravascular administration of contrast media could lead … Care Program 2 in most patients, the acute kidney injury may require renal replacement therapy or lead

324. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
     February 17, 2016 - Untitled   Source: www.effectivehealthcare.ahrq.gov Published online: February 17, 2016 Evidence-based Practice Center Systematic Review Protocol Project Title: Systematic Review Update of Venous Thromboembolism Prophylaxis in Orthopedic Surgery I. Background and Objectives for the Systematic Review Ma…

325. Diagnosis and Treatment of Tethered Spinal Cord (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-key-questions.pdf
     January 01, 2019 - young adulthood when symptoms begin.7 Delay in diagnosis or treatment in symptomatic individuals can lead

326. Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
     January 01, 2023 - Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer Comparative Effectiveness Review Number 259 Partial Breast Irradiation for Breast Cancer Executive Summary Main Points • There was no significant difference between partial breast irrad…

327. Systematic Review of Peripheral Nerve Blocks for Postoperative Pain Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-nerve-block-key-questions.pdf
     May 09, 2019 - Society (2016)20 referenced peripheral nerve blocks; however, updated, evidence-based guidance could lead

328. Topic Suggestion Description | Effective Health Care Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/measurement-and-outcomes-need-consensus-definitions-state-medicaid-programs-need-robust-hedis-and-ncqa-measures-for-all-severe-and-persistent-mental-health-conditions-consensus-definitions-would-help-answer-questions-such-as-
     November 23, 2010 - Shared decision making with patients in order to capture more information and to lead to more valid measures

329. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
     January 01, 2013 - Exposure, Outcome, and Covariate Definitions Uncertainty about the appropriate study definitions can lead … time can be summarized, and differences in the time window during which exposure is determined can lead

330. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-applicability.ppt
     June 01, 2012 - Unclear key questions lead to inconsistency in data presentation, analysis, and synthesis, which makes … decisions about which studies to include and which to exclude during the review process, as well as lead … that are fundamentally different or splitting subgroups without evidence of different effects) can lead … It is important to decide in advance what information is crucial and, when absent, will lead to the exclusion … Keeping applicability in mind throughout the review process will lead to a more useful review.

331. Coronary-Artery-Stenting Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
     February 01, 2013 - overestimates lumen dimensions; therefore, using angiography alone in the diagnosis of lesions could lead … The use of these adjunctive invasive procedures can also lead to additional invasive tests or treatments … Additionally, this review indicates that FFR-guided stenting would decrease procedural costs and would lead … Treating low- risk lesions could lead to additional invasive tests or treatments that could adversely … certainty whether a potentially life-threatening technical complication exists (i.e., one that could lead

332. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-applicability.ppt
     June 01, 2012 - Unclear key questions lead to inconsistency in data presentation, analysis, and synthesis, which makes … decisions about which studies to include and which to exclude during the review process, as well as lead … that are fundamentally different or splitting subgroups without evidence of different effects) can lead … It is important to decide in advance what information is crucial and, when absent, will lead to the exclusion … Keeping applicability in mind throughout the review process will lead to a more useful review.

333. Disposition of Comments Report for Relationship Between Use of Quality Measures and Improved Outcomes in Serious Mental Illness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-outcomes_disposition-comments.pdf
     January 15, 2015 - But I don’t think they change the conclusion that no measures of SMI have been demonstrated to lead … patients with disorder “x” should receive treatment “y” because the evidence is strong that “y” will lead … Impaired cognitive functioning would lead to recommendation for cognitive remediation (an empirically … In the longrun, penalizing providers for such outcomes could also lead to broader workforce issues … This can lead to a destabilization of patients’ conditions, a need for acute treatment and a vicious

334. Mobile Health Technology for Diabetes | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/diabetes-mobile-devices/research-protocol
     July 12, 2017 - these tools could help patients adhere to diet, exercise, and medication management plans, which could lead

335. Santa_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/santa_eccs2012.pdf
     February 01, 2013 - common in primary care practice,  that was strongly  supported by the evidence,  and that would lead

336. Maternal and Childhood Outcomes Associated With the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/outcomes-nutrition/protocol
     December 01, 2020 - education, breastfeeding support and support of and referral to other services, which are thought to lead … specific race/ethnic groups, or who are non-English speaking; (c) explorations of why/how services lead … nutrition education, breastfeeding support, and referral services) through which WIC participation may lead

337. Amended Protocol: Maternal and Childhood Outcomes Associated with the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/wic-outcomes-nutrition-protocol-amended.pdf
     October 01, 2020 - education, breastfeeding support and support of and referral to other services, which are thought to lead … specific race/ethnic groups, or who are non-English speaking; c) explorations of why/how services lead … nutrition education, breastfeeding support, and referral services) through which WIC participation may lead

338. Comparative Effectiveness of Treatments for Restless Legs Syndrome | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/restless-legs/research-protocol
     December 16, 2011 - higher for women and older people. 3,4 Different approaches to diagnosing RLS and defining its severity lead … RLS-induced sleep disruption may lead to poor daytime functioning, anxiety, and depression. … agents, anticonvulsive agents, opiates, and iron. 12 Long-term treatment with dopaminergic agents can lead

339. Musculoskeletal-Complaints-Tests-Children Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_executive.pdf
     March 01, 2012 - observed for almost all the test-disease combinations; however, the design of case-control studies may lead … .52-54 The selective inclusion of cases with established disease (i.e., JIA or pSLE) is likely to lead … inclusion of healthy controls is expected to decrease the likelihood of false positive test results and lead

340. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
     December 06, 2010 - of the synovium (a thin layer of tissue lining a joint space) and progressive erosion of bone that lead … will be reviewed for completeness and accuracy by a second senior member of the team, most often the lead