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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment_research-protocol.pdf
    September 13, 2012 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: September 13, 2012 Evidence-based Practice Center Systematic Review Protocol Project Title: Chronic Venous Ulcers: A Comparative Effectiveness Review of Treatment Modalities Amendment D…
  2. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - DEMENTIA INCLUDING ALZHEIMER'S #04 AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 04: Dementia (Including Alzheimer’s Disease) Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road R…
  3. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - limitations, including low adherence to treatment recommendations and medication diversion, which can lead
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-nomination_methods.pdf
    November 01, 2012 - Development Team Topic nomination development is typically conducted by a small team consisting of a team lead … The team lead is often a doctorally- trained person with a strong epidemiology, health services research … A poorly defined PICO can lead to development of a topic that may miss important populations, lack … A vague PICO also presents scoping challenges and may lead to a review that is too inclusive or too
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
    April 18, 2013 - Reviewer 3 ES: Treatment safety is defined by the rates of adverse effects that lead to treatment … follows: “Treatment safety is defined by the total rates of adverse effects and adverse effects that lead
  6. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - Slowing disease progression could lead to improved quality of life and reduced costs. … Slowed disease progression could lead to improved patient quality of life and reduced costs. … COPD exacerbations can lead to significant declines in lung function and progression towards respiratory
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
    January 27, 2012 - 1 Comparative Effectiveness Review Number 134 Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings Executive Summary Background Alcohol misuse, or unhealthful alcohol use, which includes the full spectrum from drinking above recommended limits (i.e., risky/hazardous drinking) to alcoho…
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-pregnant-protocol.pdf
    August 24, 2023 - 17-19 and have a greater frequency of missed well-baby check-ups.20 Postpartum depression may also lead … restriction will reduce the need to spend resources on extracting and summarizing studies that will only lead … restriction will reduce the need to spend resources on extracting and summarizing studies that will only lead
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_policymaker.pdf
    August 01, 2016 - Transitional Care Interventions To Prevent Readmissions for People With Heart Failure B A C K G R O U N D Heart failure (HF) is a major clinical and public health problem and a leading cause of hospitalization and health care costs in the United States. Despite a decline in HF-related hospitalizations during the …
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
    November 12, 2013 - For example, choosing to remove or destroy a low-grade prostatic malignancy can lead to complications … tests are often referred to as tests for publication bias; reasons other than publication bias can lead … The following team members will be involved: • The EPC director • The EPC co-director • 1 Project Lead … • 1 Co-project lead/Research Associate • 1 Local Clinical Expert • 1 Project manager 24
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
    March 01, 2011 - Simply omitting trials with data that are MNAR will lead to biased results. 26 Missing Summary … We recommend that studies missing only SDs should not be excluded, as this could lead to a biased combined … Studies missing only SDs should not be excluded as this may lead to a biased combined estimate when … Direct substitution using the largest SD is the simplest method and the most likely to lead to a conservative … However, if one is comfortable with one of the more complex methods, using it may lead to a more accurate
  12. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
    December 01, 2011 - between diagnostic tests depend on patient or specimen characteristics or the clinical scenarios that lead … toxigenic C. difficile using Bayes’ formula, then the differences in post-test probabilities might not lead … Failures with vapor disinfection systems would be possible and might lead to toxic exposures of personnel … that detect genetic residue related to C. difficile toxin production rather than the toxins per se lead
  13. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - Cervical DDD occurs when progressive changes in the cervical vertebral discs lead to loss of disc height … This may lead to different outcomes among treatment centers. … MSCs are purported to lead to cartilage regeneration because of the secretion of growth factors by … outcomes: Multilevel DDD presents a significant unmet need for new treatment options because ACDF can lead … However, the mechanism by which these cells lead to cartilage generation is still unclear.33 MSCs may
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
    November 01, 2012 - neuropsychiatric and hematologic adverse effects.23 Such adverse effects can be difficult to tolerate and can lead … regimen recommended by the FDA for antiviral-naïve patients with cirrhosis (4 weeks of dual therapy lead-in … regimens, shorter fixed duration triple therapy boceprevir therapy, and boceprevir without dual therapy lead-in … virologic response Two trials of triple therapy with boceprevir for 48 weeks (4 weeks of dual therapy lead-in … regimens on clinical outcomes in randomized trials or cohort studies is a challenge due to the long lead
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-disposition-comments.pdf
    March 25, 2024 - We agree and policy implications, which lead to harm for people that underscoring potential with ADHD … Thus, this is incredibly misleading and will lead to significant problems and false belief that we … Yes, again, substance use is awful and can lead to mortality, but so can untreated ADHD. … Misdiagnosis of ADHD not only leads to its overdiagnosis or underdiagnosis, but it can also can lead
  16. effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
    March 01, 2010 - Lead investigator, senior scientist, research fellow identified Step 3: Selected team performs general … In the human growth hormone project, the core leadership team identified the lead investigator, senior … Doing so might lead to a perception of what the ultimate project results might be, and then the methods
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/telehealth-covid-19-disposition-comments.pdf
    January 03, 2023 - for CF, the Cystic Fibrosis Foundation’s mission is to give all people with CF the opportunity to lead
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_research-protocol.pdf
    September 20, 2013 - cognition and language have led to the suggestion that beginning intensive therapy at an earlier age may lead … Individuals engage in interventions, which may lead to specific outcomes (KQ 1). … exclude case series, as additional case series (studies without a comparison group) are unlikely to lead
  19. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
    June 01, 2011 - Layout 1 Background Almost 75 million American adults— approximately one-third—have hypertension. The prevalence of hypertension increases with advancing age such that more than half of people 55 to 74 years old and approximately three-fourths of those age 75 years and older are affected. In addition to being the pr…
  20. effectivehealthcare.ahrq.gov/sites/default/files/facilitation-webcast-slides.pptx
    June 13, 2013 - the process for training facilitators. 22 Structured Facilitator Guide Activity, objective, time, lead

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