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281. Disposition of Comments_Comparative Effectiveness Review No. 249: Malnutrition in Hospitalized Adults: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-249-malnutrition-disposition-comments_0_0.pdf
     October 13, 2021 - In the introduction, we include obesity as an example of a chronic illnesses that can lead to malnutrition … We hope that the research gaps identified in this report will lead to opportunities and funding of … serum biomarkers are still being used as surrogate markers of nutritional status and oftentimes the lead … If studies were conducted, it would have provided helpful information on whether specific tools lead

282. Management of Suicidal Thoughts and Behaviors in Youth (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
     February 05, 2025 - Management of Suicidal Thoughts and Behaviors in Youth Evidence-based Practice Center Systematic Review Protocol Project Title: Management of Suicidal Thoughts and Behaviors in Youth Initial publication date: May 2, 2024 Amendment date: February 5, 2025 I. Background and Objectives for the Systematic Revi…

283. Suicidal-Thoughts-Young-People-Amendement-May-2025 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
     January 01, 2025 - Evidence-based Practice Center Systematic Review Protocol Project Title: Management of Suicidal Thoughts and Behaviors in Youth Initial Publication Date: May 2, 2024 Amendment Date(s): February 5, 2025, May 6, 2025 (Amendments Details-see Section VII) I. Background and Objectives for the Systematic Review …

284. Disposition of Comments Report for Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
     September 10, 2014 - surgeons that if a lesion is seen on multiple modalities, the choice of X to guide the biopsy will lead … However, we found that they lead to “busy” and hard to read plots and for this reason we did not retain … Because over-diagnosis is the end result of lead time (due to screening) and competing risks (specifically … Because over diagnosis is the end result of lead time (due to screening) and competing risk (specifically … There are failures in the system that lead to inadequate excision of non-palpable lesions, and that

285. Ced -Appendix-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
     May 29, 2025 - As a result, less precise diagnostic information may lead to suboptimal clinical decisions and outcomes … As a result, less precise diagnostic information may lead to suboptimal clinical decisions and outcomes

286. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-13121.pdf
     December 05, 2013 - Cervical DDD occurs when progressive changes in the cervical vertebral discs lead to loss of disc height … This may lead to different outcomes among treatment centers. … outcomes: Multilevel DDD presents a significant unmet need for new treatment options because ACDF can lead … However, the mechanism by which these cells lead to cartilage generation is still unclear.29 MSCs may … conservative treatment are considerable, and the reported adverse events appear minimal, which could lead

287. Making Healthcare Safer IV: Supply Chain Disruption Monitoring Programs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
     January 01, 2024 - Administration about permanent discontinuances or manufacturing interruptions that are likely to lead

288. Disposition of Comments_Systematic Review: Implementing Recommended Mental Health and Substance Use Screening and Counseling Interventions in Primary Care Settings for in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/behavioral-health-screening-disposition-comments.pdf
     April 09, 2025 - Disposition of Comments_Systematic Review: Implementing Recommended Mental Health and Substance Use Screening and Counseling Interventions in Primary Care Settings for in Children and Adolescents Systematic Review Disposition of Comments Report Title: Implementing Recommended Mental Health and Substance …

289. Physical Therapy for Knee Pain Secondary to Osteoarthritis Disposition of Comment Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
     November 06, 2012 - Also recommend changing the presentation of results of KQ1 in the summary (pg 50) so that the authors lead … Don’t bury your lead. … This conclusion again minimizes the effectiveness of some treatments, especially exercise and will lead … The discussion of these points and the recommendation for future research that lead from them can be … The variety of methods and results reviewed under KQ2 that prevented firm conclusions should lead the

290. Interventions for Breathlessness in Patients With Advanced Cancer: Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
     November 01, 2020 - Interventions for Breathlessness in Patients With Advanced Cancer: Evidence Summary Comparative Effectiveness Review Number 232 Interventions for Breathlessness in Patients With Advanced Cancer Evidence Summary Main Points For patients with advanced cancer: • Airflow interventions (fans) were …

291. Evidence Summary_Comparative Effectiveness Review No. 246_Management of High-Need High-Cost Patients: A "Best Fit" Framework Synthesis, Realist Review, and Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hnhc-evidence-summary.pdf
     October 01, 2021 - Evidence Summary_Comparative Effectiveness Review No. 246_Management of High-Need High-Cost Patients: A "Best Fit" Framework Synthesis, Realist Review, and Systematic Review Comparative Effectiveness Review Number 246 Management of High-Need, High-Cost Patients: A “Best Fit” Framework Synthesis, Realist Revie…

292. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
     November 01, 2016 - PREGNANCY, INCLUDING PRETERM BIRTH #12 AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 12: Pregnancy, Including Preterm Birth Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road …

293. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
     November 01, 2016 - PREGNANCY, INCLUDING PRETERM BIRTH #12 AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 12: Pregnancy, Including Preterm Birth Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane …

294. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
     December 09, 2009 - /SD of patient population); participants with underlying pathological conditions that may directly lead

295. Prioritization Criteria Methodology for Future Research Needs Proposals Within the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/future-research-prioritization-methods_research.pdf
     January 01, 2013 - effectiveness and comparative effectiveness research for clinicians, consumers, and policymakers.6 AHRQ is the lead

296. Management of Suicidal Thoughts and Behaviors in Youth (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-draft-protocol.pdf
     March 14, 2024 - Management of Suicidal Thoughts and Behaviors in Youth Evidence-based Practice Center Systematic Review Protocol Project Title: Management of Suicidal Thoughts and Behaviors in Youth I. Background and Objectives for the Systematic Review Suicide is a leading cause of death in young people and an escalating…

297. Strategies to De-escalate Aggressive Behavior in Psychiatric Patients (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_disposition-comments.pdf
     July 14, 2016 - At many places in the document, the unique aspects of this study are not highlighted, which could lead … needs to be specific to the population being treated otherwise it might not target the symptoms that lead … areas of study include the following: • Does engaging patients in their own treatment decision lead

298. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - of the brain. 17 Physicians often perform the device implantation in two separate procedures: lead

299. Disposition of Comments_Comparative Effectiveness Review No. 269_Respectful Maternity Care: Dissemination and Implementation of Perinatal Safety Culture To Improve Equitable Maternal Healthcare Delivery and Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-269-respectful-maternity-care-disposition-comments.pdf
     January 02, 2024 - Disrespectful care can lead to delayed or missed diagnoses, delayed referral to specialized care, and … ) General (cont’d) (comment above) • Discussion: note the need to recognize conditions that lead … Discussion 4.4: paragraph beginning “There is growing awareness that obstetric emergencies can lead … particular the paragraph beginning “There is growing awareness that obstetric emergencies can lead … recognizing ongoing need to identify and mitigate health systems factors that create conditions that lead

300. Hypertension-Pulmonary-Arterial Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
     April 01, 2013 - later stages of PH, RV function deteriorates, which can lessen the degree of sPAP elevation and lead … TAPSE 4 (251) 0.94 (0.82 to 1.08) SOE = Insufficient Inconsistent results between studies lead to uncertainty … placebo SOE = Insufficient (6 studies, 838 patients) Inconclusive benefit (few studies, few deaths lead … placebo SOE = Insufficient (4 studies, 1,011 patients) Inconclusive benefit (few studies, few deaths lead … monotherapy SOE = Insufficient (3 studies, 566 patients) Inconclusive benefit (few studies, few deaths lead