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241. Pneumonia-Antibiotic-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
     November 01, 2014 - Furthermore, measuring PK/PD only in the serum may lead to suboptimal antibiotic concentrations at the … In such cases, the antibiotic may not eradicate resistant organisms; this problem may in turn lead … recommendations are based largely on PK/PD studies in healthy volunteers, the recommendations may lead

242. Agenda: Impact of Healthcare Algorithms on Racial and Ethnic Disparities (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/healthcare-algorithms-agenda-for-March-23.pdf
     May 29, 2025 - tools should be developed, validated, implemented, and updated to avoid introducing bias that could lead

243. Disposition of Comments for CER 157 Appendicitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_disposition-comments.pdf
     December 14, 2015 - I would add that the ionizing radiation concern may delay the ordering of a CT which could then lead … I often miss information on the number of these diagnoses that lead to a change in treatment which … A more important result would be if other pathology was identified, and if the laparoscopy lead to … I am concerned that this study may lead to even higher reliance on radiologic testing that is clearly … and Usability Clarity and Usability: I do not believe that the report in its current form will lead

244. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
     March 10, 2010 - Methods It is not clear how information in Table 3 would lead to pre-planned 7440 meta-analysis. … Our involvement with requests for data for the review began in May 2008 when lead authors of some manuscripts … Timelines: Letters from Chalmers to lead authors: April 16 to May 2, 2008 Forwarded to Merck by lead … Events post randomization affecting analysis may lead to post randomization imbalance

245. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - This may lead to different outcomes among treatment centers. … However, the mechanism by which these cells lead to cartilage regeneration is unclear.1 MSCs may differentiate … conservative treatment are considerable, and the reported adverse events appear minimal, which could lead … the lower costs and greater symptom relief of PRP over hyaluronic acid injections will eventually lead

246. Osteoporosis-Vibration-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_research-protocol.pdf
     January 01, 2020 - 1 Source: www.effectivehealthcare.ahrq.gov Published Online: December 9, 2010 Evidence-based Practice Center Technical Brief Project Title: Whole-Body Vibration Therapy for Osteoporosis I. Background and objectives Osteoporosis is a disease of the skeletal system characterized by low bone mass and de…

247. Disposition of Comments for CER 183 Tonsillectomy for OSDB (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
     January 17, 2017 - Response Peer reviewer #1 Results Another point that is not well discussed is whether T, A or T+A lead … Does a cold versus hot technique lead to less PTH? b. … Does partial versus total tonsillectomy lead to less PTH?

248. Mobile Health Technology for Diabetes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-mobile-devices_research-protocol.pdf
     July 12, 2017 - tools could help patients adhere to diet, exercise, and medication management plans, which could lead

249. Disposition of Comments for Evidence Report #208 Part 5 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_disposition-comments.pdf
     July 26, 2012 - To be sure, the argument that making performance information available to the public will lead to a … Transparency can lead to informed decision-making, which may or may not impact “quality of care”. … consumer decisions are a product of being more engaged in their health or healthcare, but don’t always lead … presume simple causality – “Does public reporting RESULT IN improvements,” “Does public reporting LEAD … for e.g. that public reporting plus more targeted TA to low performers, or other tactic, might then lead

250. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/analytic-frameworks.ppt
     December 09, 2009 - Associations Rectangles Intermediate outcomes Rounded corners Health states Square corners Curved arrows Lead

251. Use of a Clinical Pathway To Facilitate the Translation and Utilization of AHRQ EPC Report Findings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/clinical-pathway-methods-report.pdf
     December 01, 2018 - This role is responsible for being the project lead and champion, as well as defining the problem being … Studies that appeared to meet the inclusion criteria were retrieved in full and screened by the lead … there are no potential financial or other conflicts in the guideline project funding or among the lead … B Guideline states that the lead authors have no potential financial or other conflicts, but does … C One or more lead authors, or the guideline project as a whole, is funded by a sponsor with potential

252. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - #06 Developmental Delays ADHD, and Autism AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 06: Developmental Delays, ADHD, and Autism Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaithe…

253. Methods Guide for Medical Test Reviews Chapter 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-topics_methods.pdf
     July 01, 2012 - Methods Guide for Medical Test Reviews Chapter 2 2-1 Chapter 2 Developing the Topic and Structuring Systematic Reviews of Medical Tests: Utility of PICOTS, Analytic Frameworks, Decision Trees, and Other Frameworks David Samson, M.S., Blue Cross and Blue Shield Association Karen M. Schoelles M.D., S.…

254. EHC Protocol: Making Healthcare Safer IV: Engaging Family Caregivers with Structured Communication for Safe Care Transitions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-protocol.pdf
     August 04, 2023 - in patient care due to potential disruptions in the continuity and coordination of care that often lead … in patient care due to potential disruptions in the continuity and coordination of care that often lead

255. Surveillance Report: Masks for Prevention of COVID-19 in Community and Healthcare Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-surveillance-report.pdf
     July 17, 2020 - When studies lead to a change in conclusions, the report will be updated.

256. Making Sure That Evidence Is Understood and Used (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-making-sure-evidence-understood.pdf
     July 01, 2020 - AHRQ is the lead Federal agency within the U.S.

257. Implementing Evidence-Based Screening and Counseling for Unhealthy Alcohol-Use With Epic-Based Electronic Health Record Tools: A Guide for Clinics and Health Systems Developed as Part of a Pilot Dissemination Project (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/implementation-package-unhealthy-alcohol-use-final.pdf
     September 01, 2018 - often involves the provision of multiple services; the results of a screening test, for example, can lead … reminders, though they can contribute to a program’s sustainment, require tech team staffing and lead … The team included: • Project Lead: experienced primary care clinician and researcher • Clinic Medical … the provision of multiple services; generally, the results of a screening test, for example, can lead

258. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
     June 01, 2012 - If the reference standard does not accurately predict the true status, then it is imperfect and will lead … The complex criteria, as well as the subjective nature of signs and symptoms, lead to differentially … A problem with this method occurs when modeling assumptions are incorrect and lead to biased estimates … It is present in 2 to 4 percent of middle-aged adults and can lead to daytime somnolence, cardiovascular

259. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
     June 01, 2012 - If the reference standard does not accurately predict the true status, then it is imperfect and will lead … The complex criteria, as well as the subjective nature of signs and symptoms, lead to differentially … A problem with this method occurs when modeling assumptions are incorrect and lead to biased estimates … It is present in 2 to 4 percent of middle-aged adults and can lead to daytime somnolence, cardiovascular

260. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/14_substance_abuse_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - population, including low adherence to treatment recommendations and medication diversion, which can lead … low patient adherence to treatment recommendations and medication diversion, either of which can lead