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201. Executive Summary: Healthcare Industry Waste and Use of Life (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-executive-summary.pdf
     September 01, 2023 - Executive Summary: Healthcare Industry Waste and Use of Life Comparative Effectiveness Review Number xxx Healthcare Industry Waste and Use of Life Cycle Assessment Executive Summary Main Points • Published life cycle analysis (LCA) frameworks or models were mainly adapted for healthcare using methods for esti…

202. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
     January 01, 2012 - Long-term PN can lead to serious side effects such as liver damage, the risk of which increases the … It can lead to complications such as regurgitation, coughing, choking, aspiration pneumonia, esophagitis … estimated mortality rate in infants with SBS is 30%. 40 Long-term parenteral nutrition (PN) can lead … However, experts were divided whether teduglutide would lead to more significant 10 AHRQ Healthcare … Additionally medical advances are now allowing children with conditions that put them at risk for SBS to lead

203. Ch 3-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
     September 21, 2012 - The clinical experience and expectation that differences in patient prognostic characteristics will lead … these designs incorporate heterogeneity in the risk of outcome among the subjects, they may also lead … strength of association between the exposure and outcome within strata of the effect modifier may lead … interactions.3 A useful illustration of the potential for subgroup analyses (and implied HTE) to lead

204. Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/antiplatelet-treatment/research-protocol
     November 22, 2011 - Genetic variants of the CYP2C19 locus can affect the encoded protein: some lead to normal enzymatic activity … (denoted as CYP2C19*1 alleles, corresponding to a normal metabolizer phenotype), while others lead to … and *4, all loss-of-function alleles corresponding to a nonmetabolizer phenotype), and still others lead … often referred to as a test for publication bias; however, reasons other than publication bias can lead … with no enzymatic activity (corresponding to a nonmetabolizer phenotype), and still other variants lead

205. Template for Draft Reports (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults-future_research.pdf
     July 01, 2013 - What factors lead to transitions? What works for whom? … What factors lead to transitions? What works for whom? … What factors lead to transitions? … What factors lead to transitions? … What factors lead to the transitions?

206. Alcohol-Misuse Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse_research-protocol.pdf
     April 28, 2010 - Source: www.effectivehealthcare.ahrq.gov Published Online: July 21, 2011 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Screening, Behavioral Counseling, and Referral in Primary Care to Reduce Alcohol Misuse Amendment Date(s) if applicable: Not applicable (Amendments Detail…

207. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - Long-term PN can lead to serious side effects such as liver damage, the risk of which increases the … It can lead to complications such as regurgitation, coughing, choking, aspiration pneumonia, esophagitis … , at a cost of more than $100,000 per patient per year.61 Long-term parenteral nutrition (PN) can lead … Additionally, medical advances are now allowing children with conditions that put them at risk of SBS to lead … However, whether teduglutide would lead to more significant improvements in health outcomes—such as

208. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/introduction-to-user-guide-overview.pptx
     January 01, 2013 - groups with the greatest needs (the elderly, the disabled, and patients with complex conditions) Can lead … Uncertainty about the effects of treatment on patient outcomes may lead to the overuse of ineffective

209. Antenatal Care | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/antenatal-care
     April 07, 2020 - Home » Get Involved » Nominated Topics » Topic Suggestion Description Topic Suggestion Description Date submitted: April 7, 2020 Download Topic Suggestion Disposition [PDF · 177.4 KB] Antenatal Care 1. What is the decision or change you are facing or struggling with …

210. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0095_04-10-2009.pdf
     January 01, 2009 - Effective Health Care Topic Number: 0142 Document Completion Date: 7-15-09 1 Results of Topic Selection Process & Next Steps  Noninvasive diagnosis of coronary artery disease in women will be developed as a systematic review by the Effective Health Care (EHC) Program.  When key questi…

211. Topic 0533 Postpartum Hemorrhage NSD FINALsj (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0652-131114.pdf
     May 15, 2013 - Topic 0533 Postpartum Hemorrhage NSD FINALsj Postpartum Hemorrhage Nomination Summary Document Results of Topic Selection Process & Next Steps …

212. Disposition of Comments: Comparative Effectiveness Review No. 238 Cervical Ripening in the Outpatient Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
     March 22, 2021 - Removing all non-US studies would lead to insufficient evidence across the board.

213. Imaging Techniques for Treatment Evaluation for Metastatic Breast Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/breast-cancer-imaging/research-protocol
     December 17, 2013 - the type and results of imaging may strongly affect patient outcomes. 2,3 Inappropriate use could lead … with potentially avoidable mastectomies. 6-8 Alternatively, inappropriate use of imaging may also lead … to undertreatment if additional foci of disease are not identified and these lead to disease progression

214. breast-cancer-imaging-protocol-131217 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-imaging_research-protocol.pdf
     December 17, 2013 - the type and results of imaging may strongly affect patient outcomes.2, 3 Inappropriate use could lead … and with potentially avoidable mastectomies.6-8 Alternatively, inappropriate use of imaging may also lead … to undertreatment if additional foci of disease are not identified and these lead to disease progression

215. S89 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
     October 01, 2007 - Experi- ence in previous pilot analyses suggested that vaguely defined outcomes would lead to false signaling … Secular trends in disease, or in diag- nostic or coding practices, may lead to false signaling or failure … Outcomes that are broadly defined may lead to dampening of true signals, whereas outcomes with insidious … Care • Volume 45, Number 10 Suppl 2, October 2007 © 2007 Lippincott Williams & WilkinsS94 commonly lead

216. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
     June 06, 2011 - MCG machine, five ECG wires with electrodes are attached to the patient at the four standard limb-lead … and precordial-lead V5 positions. … An automatic simultaneous 2-lead (leads V5 and II) ECG sampling is recorded for 82 seconds with amplification … Comparison of a two-lead, computerized, resting ECG signal analysis device, the MultiFunction-CardioGram

217. Use of Analytic Hierarchy Process to elicit stakeholder preferences for prioritizing research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/mcda-krishnan.pdf
     August 27, 2012 - Use of Analytic Hierarchy Process to elicit stakeholder preferences for prioritizing research Slide 1 Use of Analytic Hierarchy Process to elicit stakeholder preferences for prioritizing research August 27, 2012 Jerry A. Krishnan, MD, PhD (jakris@uic.edu) Professor of Medicine and Public Health Associate V…

218. S158 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
     October 01, 2007 - measured in the administrative claims data (smoking, obesity, aspirin use, education, and income) would lead

219. White Paper: Narratively Describing Effects of Interventions in Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-roadmap-interventions.pdf
     November 01, 2020 - confidence interval also includes an important benefit/harm/no effect Option 1 [Intervention] may lead … Option 2 [Intervention] may lead to [better outcome]. … Option 3 [Intervention] may lead to [better / worse outcome / little or no difference].

220. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-risk-bias.ppt
     June 01, 2012 - resulting from: Study design Conduct of study Reporting of study findings These systematic errors can lead … focuses on systematic errors that result from study design, conduct, and reporting—any of which can lead … This may lead to biased assessment of the test characteristics. … the threshold value for the index test that maximizes the sensitivity and specificity of the test may lead … While inadequate reporting does not in itself lead to systematic bias, it does limit a reviewer’s ability