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181. Disposition of Comments: Technical Brief No. 38_Automated Entry Patient Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-38-chronic-conditions-comments.pdf
     March 01, 2021 - It is hard to imagine how self-monitoring alone would lead to positive health outcomes; only when patient … For example, hyper-tracking that could lead to emotional distress? … is prevalent in chronic disease populations and excessive monitoring with a wearable device could lead … Though this may lead to a lot of repetition- it will allow for easier navigation between sections of … As standard for synthesizing studies, we have analyzed risk of bias that may lead to uncertainty

182. Effectiveness of Treatments for Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetic-neuropathy_research-protocol.pdf
     May 09, 2016 - Recurrent ulcers and infections may eventually lead to amputation of the lower extremities. … Painful neuropathy may lead to reduced ability to perform daily activities and a decrease in quality … Loss of sensation increases risk for foot injury, delays treatment and can lead to foot and leg ulceration … Ulcers and infections may eventually lead to amputation of the lower extremities.

183. Comparative Effectiveness Review No. 241_Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
     October 01, 2021 - This may lead to paralysis or reduced extremity muscle force and increased spasticity, which can greatly

184. Underperformance of Contemporary Phase III Oncology Trials and Strategies for Improvement | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/grant-manuscripts/underperformance-abstract

185. Treatments for Fecal Incontinence: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
     July 01, 2016 - issues (impaction, large bowel obstruction) Sacral nerve stimulation Infection, pain, electrode or lead

186. Appendicitis Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
     December 09, 2013 - appendicitis the most common non-obstetric emergency during pregnancy.4, 5 Untreated appendicitis can lead … Perforation of the appendix can lead to intra-abdominal infection, sepsis, the formation of intraperitoneal … studies at low risk of bias or inconsistencies among groups of studies at different risk of bias will lead … tests are often referred to as tests for publication bias; reasons other than publication bias can lead … The following team members will be involved: • The EPC director • The EPC co-director • 1 Project Lead

187. Searching for Studies (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-search-strategies.ppt
     June 01, 2012 - should be noted that searching is often an iterative process, as findings from one type of search can lead … Use of methodological search filters to identify diagnostic accuracy studies can lead to the omission … Use of methodological search filters to identify diagnostic accuracy studies can lead to the omission … Use of methodological search filters to identify diagnostic accuracy studies can lead to the omission

188. Major-Depressive-Disorder Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
     December 01, 2015 - SGAs and interpersonal psychotherapy did not lead to statistically different response or remission rates … SGA monotherapy and short-term PSYD monotherapy did not lead to statistically different rates of remission … SGAs and omega-3 fatty acids did not lead to significantly different rates of overall discontinuation … Lack of information about harms can lead to a biased knowledge base and the potential for decisions

189. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
     January 01, 2007 - Layout 1 Background More than 65 million American adults— approximately one-third—have hypertension. The prevalence of hypertension increases with advancing age such that more than half of people 60-69 years of age and approximately three- fourths of those 70 years of age and older are affected. In addition to being…

190. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - PREGNANCY, INCLUDING PRETERM BIRTH #12 AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 12: Pregnancy, Including Preterm Birth Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither R…

191. Contrast-Induced Nephropathy (CIN): Current State of the Evidence on Contrast Media and Prevention of CIN (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
     August 01, 2016 - Contrast-Induced Nephropathy (CIN): Current State of the Evidence on Contrast Media and Prevention of CIN Focus of This Summary This is a summary of two systematic reviews. One review evaluated the evidence regarding the comparative effects of different contrast media in patients requiring diagnostic imaging studies…

192. Facilitating the Implementation of EPC Reports_Methods Research Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-facilitating-implementation-pilot.pdf
     October 01, 2019 - Facilitating the Implementation of EPC Reports_Methods Research Report Methods Research Report Facilitating the Implementation of EPC Reports in Learning Health Systems Engaged in Quality Initiatives: an EPC Pilot Project on ADHD Methods Research Report Facilitating the Im…

193. Technical Brief Protocol: Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Diseases (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/community-health-worker-protocol.pdf
     March 26, 2019 - Third, certification may lead to the creation of hierarchies among CHWs such that uncertified CHWs are

194. Research Protocol: Breast Reconstruction After Mastectomy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
     April 09, 2020 - However, ADMs might lead to more postoperative complications, such as infection and seroma.20-24 Regardless … postmastectomy radiation therapy.26 But, AR requires a larger operation, leads to greater scarring, and may lead … use* o Necrosis, such as of the nipple or of the flap* o Animation deformity* o Complications that lead … of the flap* o Harms to area of flap harvest (e.g., hernia, bulge formation)* o Complications that lead

195. Head-Neck-Cancer-Update Consumer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_consumer.pdf
     August 01, 2015 - This can affect how much saliva is made and can lead to dry mouth.

196. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substanceabuse_hi_impact.pdf
     January 01, 2012 - associated with limitations, including low patient adherence and medication diversion, each of which can lead … associated with limitations, including low patient adherence and medication diversion, each of which can lead

197. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
     March 28, 2019 - These issues lead to questions about the ratings of low risk of bias for the individual studies and … , in turn, lead to questions about the appropriateness of the strength of evidence ratings. … Attempts to search for only a subgroup would lead to a narrower search and potentially missing papers … Attempts to search for only a subgroup would lead to a narrower search and potentially missing papers … Attempts to search for only a subgroup would lead to a narrower search and potentially missing papers

198. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/data-extraction.ppt
     January 01, 2009 - AHRQ Slide Template 2009 Data Extraction Agency for Healthcare Research and Quality (AHRQ) Training Modules for Methods Guide for Effectiveness and Comparative Effectiveness Reviews Data Extraction Systematic Review Process Overview Systematic Review Process Overview This slide illustrates the steps in the …

199. Disposition of Comments Report for Acute Migraine Treatment in Emergency Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
     November 27, 2012 - references for (or specific examples with references) where the “synthesis of this literature could lead

200. Outcomes of Alternative Payment Models: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/alternative-payment-models/protocol