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141. Migraine-Adults-Executive-130408 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
     April 01, 2013 - life.6 Treatment safety is defined by the total rates of adverse effects and adverse effects that lead

142. Omega-3 Fatty Acids and Cardiovascular Disease: A Review of the Research for Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_consumer.pdf
     July 01, 2017 - Having high cholesterol levels and high blood pressure can increase the risk of CV disease and could lead

143. Behavioral Programs To Help Manage Type 2 Diabetes: A Review of the Research for Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_consumer.pdf
     November 01, 2016 - » Eye problems and possibly blindness » Nerve damage » Foot problems, which in severe cases may lead

144. Behavioral Programs To Help Manage Type 1 Diabetes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_consumer-2016.pdf
     January 01, 2016 - » Eye problems and possibly blindness » Nerve damage » Foot problems, which in severe cases may lead

145. Rotator-Cuff-Tear-Surveillance-140925 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-surveillance-140925.pdf
     February 01, 2014 - surgical repair compared to late surgical repair (i.e., nonoperative intervention followed by surgery) lead … • Key question # 4: Does operative repair compared with nonoperative treatment lead to improved … Cycle 1 (1st assessment) In total, 9 experts (6 CER-specific: lead author, clinical content experts … For larger tears (>1 cm), double- row repair methods lead to significantly lower retear rates when … Does operative repair compared with nonoperative treatment lead to improved health-related quality of

146. Ch 11-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
     January 03, 2012 - presence of uncertainty.5 Uncertainty about the most appropriate way to define drug exposure can lead … This result can lead either to insight into potential unaddressed bias or confounding, or it could be … time can be summarized, and differences in the time window during which exposure is determined can lead … For example, an outcome definition of all cardiovascular events including angina could lead to a different … oversampling of cases exposed to one of the drugs under study (or, similarly, an undersampling) can lead

147. S158 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
     October 01, 2007 - measured in the administrative claims data (smoking, obesity, aspirin use, education, and income) would lead

148. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
     March 29, 2011 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: March 29, 2011 EPC Protocol – Version 8 – 12.22.10 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Treatment for Phenylketonuria Amen…

149. Methods Guide for Medical Test Reviews Chapter 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
     July 01, 2012 - This is the case primarily because most treatments lead directly to the intended result (or to adverse … add-on, triage Desciption of index test performance and interpretation; how results of index test lead … strategy Desciption of comparator test performance and interpretation; how results of comparator test lead

150. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia_hi_impact.pdf
     January 01, 2012 - increase in short-term expenditures that PET requires, but some experts noted that early detection might lead

151. Use of Analytic Hierarchy Process to elicit stakeholder preferences for prioritizing research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/mcda-krishnan.pdf
     August 27, 2012 - Use of Analytic Hierarchy Process to elicit stakeholder preferences for prioritizing research Slide 1 Use of Analytic Hierarchy Process to elicit stakeholder preferences for prioritizing research August 27, 2012 Jerry A. Krishnan, MD, PhD (jakris@uic.edu) Professor of Medicine and Public Health Associate V…

152. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
     January 01, 2012 - This may lead to different outcomes among treatment centers. … MSCs are purported to lead to the regeneration of cartilage due to either the secretion of growth factors … However, the mechanism by which these cells lead to cartilage generation is still unclear. 1 MSCs … The experts thought that tofacitinib could improve health outcomes in patients with RA and might lead … the specialist office to primary care offices, which might allow for earlier treatment, but could lead

153. breast-biopsy-update-130920 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
     September 20, 2013 - low risk of bias or inconsistencies among groups of studies at different levels of risk of bias will lead … tests are often referred to as tests for publication bias, reasons other than publication bias can lead … methodological  search  filters  to  identify   diagnostic  accuracy  studies  can  lead … following team members will be involved: • The EPC Director • The EPC Codirector • One Project Lead … • One Coproject Lead/Research Associate • Two Research Associates • One Project Manager • One Program

154. Disposition of Comments Report for CER 132 Combination Therapy Versus Intensification of Statin Monotherapy: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
     September 01, 2014 - dose plus another lipid lowering drug have demonstrated that this “add on” combination therapy can lead … In our view, LDL lowering does not seem to lead to decreased clinical risk – would be extrapolating … dose plus another lipid lowering drug have demonstrated that this “add on” combination therapy can lead … , it really has nothing to do with the current topic Table I on page 32: COMMENT: Fibrates can lead … These trials have demonstrated that this “add on” combination therapy can lead to superior lipid outcomes

155. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - This may lead to different outcomes among treatment centers. … MSCs are purported to lead to cartilage regeneration because of the secretion of growth factors by … However, the mechanism by which these cells lead to cartilage generation is still unclear. 1 MSCs … that PRP injections might not have a durable response and that a need for repeated injections could lead … The experts thought that tofacitinib could improve health outcomes in patients with RA and might lead

156. Public-Reporting-Quality-Improvement Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
     August 17, 2011 - Key Questions for Objective 2 Question 3 Does public reporting lead to change in health care … Question 4 Does public reporting lead to change in the behavior of patients, their representatives … Change is an intermediate outcome included in KQ 3, as it is not a given that all change will lead … However, this change in delivery may or may not necessarily lead to improvement in quality of care—

157. Topic 0533 Postpartum Hemorrhage NSD FINALsj (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0652-131114.pdf
     May 15, 2013 - Topic 0533 Postpartum Hemorrhage NSD FINALsj Postpartum Hemorrhage Nomination Summary Document Results of Topic Selection Process & Next Steps …

158. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0095_04-10-2009.pdf
     January 01, 2009 - Effective Health Care Topic Number: 0142 Document Completion Date: 7-15-09 1 Results of Topic Selection Process & Next Steps  Noninvasive diagnosis of coronary artery disease in women will be developed as a systematic review by the Effective Health Care (EHC) Program.  When key questi…

159. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
     November 22, 2011 - Genetic variants of the CYP2C19 locus can affect the encoded protein: some lead to normal enzymatic … activity (denoted as CYP2C19*1 alleles, corresponding to a normal metabolizer phenotype), while others lead … and *4, all loss-of-function alleles corresponding to a nonmetabolizer phenotype), and still others lead … often referred to as a test for publication bias; however, reasons other than publication bias can lead … with no enzymatic activity (corresponding to a nonmetabolizer phenotype), and still other variants lead

160. Evidence Summary_Comparative Effectiveness Review No. 247_Interventional Treatments for Acute and Chronic Pain: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
     September 01, 2021 - • Lead migration occurred in 14 to 24 percent of patients (2 trials, N=224), serious device-related … Evidence on harms was limited, but lead migration was common following occipital nerve stimulation placement