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  1. effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
    January 01, 2013 - death) are less likely to be treated with a multitude of preventive treatments; thus, frailty would lead … there is the potential that treatments will be assessed differently for cases and controls, which will lead
  2. effectivehealthcare.ahrq.gov/sites/default/files/deliberative-methods-facilitation-slides-text.pdf
    May 29, 2025 - • Structured Facilitator Guide o Activity, objective, time, lead
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-d.xlsx
    January 01, 2023 - JCOG9206-2 Grade 3 to 5 AEs Low High Low Low Low Some concerns high discontinuation rate could lead to … avoided as an endpoint in clinical trials.8 Therefore, this information on response may inappropriately lead
  4. effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
    September 21, 2012 - The clinical experience and expectation that differences in patient prognostic characteristics will lead … these designs incorporate heterogeneity in the risk of outcome among the subjects, they may also lead … strength of association between the exposure and outcome within strata of the effect modifier may lead … interactions.3 A useful illustration of the potential for subgroup analyses (and implied HTE) to lead
  5. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Long-term PN can, however, lead to serious side effects, such as liver damage, the risk of which increases … 1990s, at a cost of more than $100,000 per patient per year.3 Long-term parenteral nutrition (PN) can lead … consume a large amount of health care resources and if teduglutide is effective this would potentially lead
  6. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - Long-term PN can lead to serious side effects, such as liver damage, the risk of which increases the … 1990s, at a cost of more than $100,000 per patient per year.3 Long-term parenteral nutrition (PN) can lead … consume a large amount of health care resources and if teduglutide is effective this would potentially lead
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-disposition-comments.pdf
    May 14, 2025 - : the cancer type, the type of study (diagnostic or pre-diagnostic), the stage of the cases, the lead … I do worry that the division by type of analyte in Figure 2 could lead some to the conclusion that, … interpret the fact that MCST-detectable cancers have worse survival: 1) the tests are unlikely to lead … Screening is a well-defined process; due to well-recognized lead time biases, simply finding a cancer … does not equate benefit and can sometimes lead to harm.
  8. Hesse (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/hesse.pdf
    January 01, 2010 - o The right data  should spur community  improvement efforts • Tensions o Do too many data lead
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0119_06-17-2009.pdf
    January 01, 2009 - Effective Health Care Topic Number: 0160 Document Completion Date: 1-12-10 1 Results of Topic Selection Process & Next Steps  Pharmacologic therapy versus medical foods and nondietary approaches for the treatment of phenylketonuria (PKU) will go forward for refinement as a systematic review. …
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-270-bimp-executive-summary.pdf
    May 01, 2024 - • Children/adolescents: a combination of CBT, biofeedback, and relaxation training may lead to lower
  11. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
    December 01, 2011 - the new evidence (78 new studies, 87 articles) we found during the update of the 2007 report did not lead … the new evidence (78 new studies, 87 articles) we found during the update of our 2007 report did not lead … also evaluate further whether different formulations (i.e., controlled release vs. immediate release) lead
  12. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-3.pdf
    July 01, 2023 - AI Bias Can Lead … socioeconomic status, race, ethnic background, disability, religion, gender or sexual orientation, and lead … algorithms should be developed, validated, implemented, and updated to avoid introducing bias that could lead … AI Bias Can Lead to Health Disparities Look Deeper with More Eyes Introducing ScHARE the Platform
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-risk-bias.ppt
    June 01, 2012 - resulting from: Study design Conduct of study Reporting of study findings These systematic errors can lead … focuses on systematic errors that result from study design, conduct, and reporting—any of which can lead … This may lead to biased assessment of the test characteristics. … the threshold value for the index test that maximizes the sensitivity and specificity of the test may lead … While inadequate reporting does not in itself lead to systematic bias, it does limit a reviewer’s ability
  14. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-risk-bias.ppt
    June 01, 2012 - resulting from: Study design Conduct of study Reporting of study findings These systematic errors can lead … focuses on systematic errors that result from study design, conduct, and reporting—any of which can lead … This may lead to biased assessment of the test characteristics. … the threshold value for the index test that maximizes the sensitivity and specificity of the test may lead … While inadequate reporting does not in itself lead to systematic bias, it does limit a reviewer’s ability
  15. S89 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
    October 01, 2007 - Experi- ence in previous pilot analyses suggested that vaguely defined outcomes would lead to false signaling … Secular trends in disease, or in diag- nostic or coding practices, may lead to false signaling or failure … Outcomes that are broadly defined may lead to dampening of true signals, whereas outcomes with insidious … Care • Volume 45, Number 10 Suppl 2, October 2007 © 2007 Lippincott Williams & WilkinsS94 commonly lead
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-roadmap-interventions.pdf
    November 01, 2020 - confidence interval also includes an important benefit/harm/no effect Option 1 [Intervention] may lead … Option 2 [Intervention] may lead to [better outcome]. … Option 3 [Intervention] may lead to [better / worse outcome / little or no difference].
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-imaging_research-protocol.pdf
    December 17, 2013 - the type and results of imaging may strongly affect patient outcomes.2, 3 Inappropriate use could lead … and with potentially avoidable mastectomies.6-8 Alternatively, inappropriate use of imaging may also lead … to undertreatment if additional foci of disease are not identified and these lead to disease progression
  18. effectivehealthcare.ahrq.gov/sites/default/files/introduction-to-user-guide-overview.pptx
    January 01, 2013 - groups with the greatest needs (the elderly, the disabled, and patients with complex conditions) Can lead … Uncertainty about the effects of treatment on patient outcomes may lead to the overuse of ineffective
  19. effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - #06 Developmental Delays ADHD, and Autism AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 06: Developmental Delays, ADHD, and Autism Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 G…
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_surveillance.pdf
    January 01, 2013 - recommendations of any relevant new studies; 7 subject matter experts responded, including the project lead … Other Experts Conclusion from SCEPC KQ1a: Does a screening-based program for open-angle glaucoma lead … KQ2a: Does a screening-based program for open-angle glaucoma lead to improvements in patient-reported … KQ4a: Does a screening-based program for open-angle glaucoma lead to reductions in intraocular pressure … New Evidence: KQ2a: Does a screening-based program for open-angle glaucoma lead

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