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401. Chapter 1: Introduction to the Methods Guide for Medical Test Reviews | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-introduction/methods
     December 01, 2019 - This is the case primarily because most treatments lead directly to the intended result (or to adverse … add-on, triage Desciption of index test performance and interpretation; how results of index test lead … strategy Desciption of comparator test performance and interpretation; how results of comparator test lead

402. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - PREGNANCY, INCLUDING PRETERM BIRTH #12 AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 12: Pregnancy, Including Preterm Birth Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither R…

403. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
     January 01, 2007 - Layout 1 Background More than 65 million American adults— approximately one-third—have hypertension. The prevalence of hypertension increases with advancing age such that more than half of people 60-69 years of age and approximately three- fourths of those 70 years of age and older are affected. In addition to being…

404. Contrast-Induced Nephropathy (CIN): Current State of the Evidence on Contrast Media and Prevention of CIN (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
     August 01, 2016 - Contrast-Induced Nephropathy (CIN): Current State of the Evidence on Contrast Media and Prevention of CIN Focus of This Summary This is a summary of two systematic reviews. One review evaluated the evidence regarding the comparative effects of different contrast media in patients requiring diagnostic imaging studies…

405. Environmental, Clinical and Economic Outcomes of Hospital Resources to Prevent Hospital-Acquired Infections (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prevent-hai-draft-report.pdf
     January 16, 2025 - ................................................................. 25 4.1.3.5 Electrocardiographic Lead … reprocessed alternatives, this may or may not be the case, and they may increase hospital costs and lead … 1 NRCS/model Intermittent pneumatic compression sleeves NR 1 LCA 1 LCA Electrocardiographic lead … Environmental service workers cleaned reusable lead wires with Clorox Healthcare Germicidal Wipes in … Infection rates in intensive care units by electrocardiographic lead wire type: Disposable vs reusable

406. breast-biopsy-update-130920 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
     September 20, 2013 - low risk of bias or inconsistencies among groups of studies at different levels of risk of bias will lead … tests are often referred to as tests for publication bias, reasons other than publication bias can lead … methodological  search  filters  to  identify   diagnostic  accuracy  studies  can  lead … following team members will be involved: • The EPC Director • The EPC Codirector • One Project Lead … • One Coproject Lead/Research Associate • Two Research Associates • One Project Manager • One Program

407. S1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/s1.pdf
     October 01, 2007 - As the lead Federal agency for improving the quality, safety, and effectiveness of health care, AHRQ’

408. Public-Reporting-Quality-Improvement Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
     August 17, 2011 - Key Questions for Objective 2 Question 3 Does public reporting lead to change in health care … Question 4 Does public reporting lead to change in the behavior of patients, their representatives … Change is an intermediate outcome included in KQ 3, as it is not a given that all change will lead … However, this change in delivery may or may not necessarily lead to improvement in quality of care—

409. Disposition of Comments Report for CER 132 Combination Therapy Versus Intensification of Statin Monotherapy: An Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
     September 01, 2014 - dose plus another lipid lowering drug have demonstrated that this “add on” combination therapy can lead … In our view, LDL lowering does not seem to lead to decreased clinical risk – would be extrapolating … dose plus another lipid lowering drug have demonstrated that this “add on” combination therapy can lead … , it really has nothing to do with the current topic Table I on page 32: COMMENT: Fibrates can lead … These trials have demonstrated that this “add on” combination therapy can lead to superior lipid outcomes

410. Disposition of Comments_Technical Brief No. 43: Measuring Healthcare Organization Characteristics in Cancer Care Delivery Research (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/organization-cancer-care-disposition-comments.pdf
     June 20, 2023 - This line has been edited for clarity. 3 Peer Reviewer #7 Executive Summary Think a lead-in paragraph … & Affiliation Section Comment Response 7 Peer Reviewer #7 Executive Summary, Background The lead-in … Impressive list, and makes me think that one simple lead-in on high for the rationale for the Integrated … question 4, the authors describe the most common themes identified, stating "these and other gaps" lead … The standardization that the Integrated Framework employs could help lead to more uniformity across

411. Does the use of Cytochrome P450 2C19 (CYP2C19) testing to predict response to clopidogrel in people: (1) with acute coronary syndrome, (2) who have suffered other cardiovascular disease-related events (e.g., ischemic stroke, symptomatic… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/does-the-use-of-cytochrome-p450-2c19-cyp2c19-testing-to-predict-response-to-clopidogrel-in-people-1-with-acute-coronary-syndrome-2-who-have-suffered-other-cardiovascular-disease-related-events-eg-ischemic-stroke-symptomatic-
     November 01, 2017 - stroke, symptomatic peripheral arterial disease), or (3) undergoing percutaneous coronary intervention, lead

412. EPC Methods: An Exploration of Methods and Context for the Production of Rapid Reviews | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/rapid-review-production/white-paper
     November 01, 2017 - Because there may not be lead time before the review is needed and the end-user may need the review urgently

413. Evidence Summary_Comparative Effectiveness Review No. 247_Interventional Treatments for Acute and Chronic Pain: Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
     September 01, 2021 - • Lead migration occurred in 14 to 24 percent of patients (2 trials, N=224), serious device-related … Evidence on harms was limited, but lead migration was common following occipital nerve stimulation placement

414. Technical Brief Protocol: Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Diseases (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/community-health-worker-protocol.pdf
     March 26, 2019 - Third, certification may lead to the creation of hierarchies among CHWs such that uncertified CHWs are

415. Facilitating the Implementation of EPC Reports_Methods Research Report (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-report-facilitating-implementation-pilot.pdf
     October 01, 2019 - Facilitating the Implementation of EPC Reports_Methods Research Report Methods Research Report Facilitating the Implementation of EPC Reports in Learning Health Systems Engaged in Quality Initiatives: an EPC Pilot Project on ADHD Methods Research Report Facilitating the Im…

416. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
     March 09, 2010 - their families, and clinicians are especially excited with the new DMARDs, which they believe may lead … evidence would help these other health care providers in making evidence-based decisions and likely lead … Initially, data will be synthesized qualitatively with a particular focus on design issues that may lead

417. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/substanceabuse_hi_impact.pdf
     January 01, 2012 - associated with limitations, including low patient adherence and medication diversion, each of which can lead … associated with limitations, including low patient adherence and medication diversion, each of which can lead

418. Healthcare Industry Waste and Lifecycle Assessment | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/lifecycle-assessment
     September 01, 2023 - established pathways for recycling. 12 In addition to environmental benefits and resource efficiency can lead … has addressed any variation in modelling parameters, methods, data collection and databases that may lead

419. Diagnosis of Right Lower Quadrant Pain and Suspected Acute Appendicitis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/appendicitis/research-protocol
     December 01, 2019 - appendicitis the most common non-obstetric emergency during pregnancy. 4,5 Untreated appendicitis can lead … Perforation of the appendix can lead to intra-abdominal infection, sepsis, the formation of intraperitoneal … studies at low risk of bias or inconsistencies among groups of studies at different risk of bias will lead … tests are often referred to as tests for publication bias; reasons other than publication bias can lead … The following team members will be involved: The EPC Director The EPC Co-director 1 Project Lead

420. Statistical Design and Analytic Considerations for N-of-1 Trials (Chapter 4) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-1
     August 01, 2019 - It minimizes the consequences of early termination from the trial that might otherwise lead to an unbalanced … In addition to the potential effect on reported outcomes, knowledge of treatment identity may lead some … Conversely, not using a washout might compromise the validity of the estimated treatment effect and lead … If not controlled for, carryover may lead to bias in the estimated treatment effects, with a tendency