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381. Disposition of Comments Report for Interventions for Feeding and Nutrition in Cerebral Palsy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cerebral-palsy-feeding_disposition-comments.pdf
     March 20, 2013 - review will help policy makers and researchers understand what types of studies are essential to lead … palsy face many nutritional challenges and “frequently have feeding and swallowing problems that may lead

382. For patients with Crohn's disease, what treatments or therapies, alone or in conjunction with one another, provide the highest rate of disease management with the lowest risk of long term complications, particularly in young women? | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-patients-with-crohns-disease-what-treatments-or-therapies-alone-or-in-conjunction-with-one-another-provide-the-highest-rate-of-disease-management-with-the-lowest-risk-of-long-term-complications-particularly-in-young-wome
     November 01, 2017 - Various GI docs have lead me in multiple directions highlighting the need for sunlight shed on this issue

383. COPD is common and respiratory failure due to COPD is an increasingly common disorder. Use of non-invasive positive pressure ventilation (NPPV) for patients with respiratory failure due to exacerbatons of COPD. Several trials and… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/copd-is-common-and-respiratory-failure-due-to-copd-is-an-increasingly-common-disorder-use-of-non-invasive-positive-pressure-ventilation-nppv-for-patients-with-respiratory-failure-due-to-exacerbatons-of-copd-several-trials-an
     November 01, 2017 - Use of NPPV requires adequate staff and physician training and can lead to complications (e.g., aspiration

384. The Empirical Evidence of Bias in Trials Measuring Treatment Differences | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/treatment-effects-bias/research
     November 01, 2017 - Future studies evaluating the impact of biases on treatment effect should follow the lead of the BRANDO

385. Using Deliberative Methods to Engage the Public: Facilitating a Deliberative Session (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/deliberative-methods-facilitation-slides-text.pdf
     January 11, 2017 - • Structured Facilitator Guide o Activity, objective, time, lead

386. Public Reporting as a Quality Improvement Strategy: A Systematic Review of the Multiple Pathways Public Reporting May Influence Quality of Health Care | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/public-reporting-quality-improvement/research-protocol
     December 01, 2019 - Key Questions for Objective 2 Question 3 Does public reporting lead to change in health care delivery … Question 4 Does public reporting lead to change in the behavior of patients, their representatives, … Change is an intermediate outcome included in KQ 3, as it is not a given that all change will lead to … However, this change in delivery may or may not necessarily lead to improvement in quality of care—the

387. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
     January 01, 2014 - This may lead to different outcomes among treatment centers. … Overall, experts did not think that pegloticase use would lead to a major shift in the understanding … In general, experts did not think that rilonacept would lead to a major shift in understanding and … However, the mechanism by which these cells lead to cartilage generation is still unclear. 31 MSCs … In general, the experts did not think that belimumab would lead to a major shift in the understanding

388. Hypofractionated Radiation Therapy for Localized Prostate Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-key-question.pdf
     December 19, 2023 - Hypofractionated Radiation Therapy for Localized Prostate Cancer 1 Hypofractionated Radiation Therapy for Localized Prostate Cancer Background One in eight men in the United States will develop prostate cancer in his lifetime1; prostate cancer is the leading type of cancer among men (age-adjusted incidence rat…

389. Topic Nomination: Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia 1.Questions to Consider 1. What is the comparative efficacy and effectiveness of currently available and emerging treatments for lower urinary tract… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/topic-nomination-lower-urinary-tract-symptoms-secondary-to-benign-prostatic-hyperplasia-1questions-to-consider-1-what-is-the-comparative-efficacy-and-effectiveness-of-currently-available-and-emerging-treatments-for-lower-uri
     November 01, 2017 - BPH can lead to a progressive decrease in patient self esteem, disturbance of sleep, disruption of sex … aimed at the underlying pathophysiology of LUTS/BPH The identification of disease "phenotypes" and lead

390. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - Slowing disease progression could lead to improved quality of life in patients and reduced costs. … Slowed disease progression could lead to improved patient quality of life and reduced costs. … COPD exacerbations can lead to significant declines in lung function and progression towards respiratory

391. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pepticulcer_hi_impact.pdf
     January 01, 2012 - Long-term PN can lead to serious side effects ES-5 AHRQ Healthcare Horizon Scanning System … estimated mortality rate in infants with SBS is 30%. 24 Long-term parenteral nutrition (PN) can lead … Additionally medical advances are now allowing children with conditions that put them at risk for SBS to lead

392. Comparative Effectiveness of Treatment for Phenylketonuria | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/phenylketonuria/research-protocol
     December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

393. Respectful Maternity Care | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/respectful-maternity-care/research
     October 01, 2024 - A reliable metric informed by a standard definition could lead to further evaluation and implementation

394. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
     February 01, 2018 - (Lead) IQVIA Zhaohui Su, Ph.D. OM1, Inc. Daniel Westreich, Ph.D. … Competing risks can lead to missing data in certain settings; sometimes a study may be interested in … a mastectomy, can be regarded as a variety of missing data; in other cases, competing risks do not lead … documentation of care provided in either inpatient or outpatient settings, but not both, which can lead … This, in turn, may well lead to incomplete adjustment for confounding by age (in a final regression

395. Methods Guide for Medical Test Reviews Chapter 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
     July 01, 2012 - This is the case primarily because most treatments lead directly to the intended result (or to adverse … add-on, triage Desciption of index test performance and interpretation; how results of index test lead … strategy Desciption of comparator test performance and interpretation; how results of comparator test lead

396. PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-antigen-3-gene/research
     December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

397. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - This may lead to different outcomes among treatment centers. … MSCs are purported to lead to cartilage regeneration because of the secretion of growth factors by … However, the mechanism by which these cells lead to cartilage generation is still unclear. 1 MSCs … that PRP injections might not have a durable response and that a need for repeated injections could lead … The experts thought that tofacitinib could improve health outcomes in patients with RA and might lead

398. Summary Report Closing the Quality Gap: Revisiting the State of the Science (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/closing-quality-gap-summary_research.pdf
     January 01, 2013 - Lead EPC Investigator and Associate Editor, Closing the Quality Gap Series Stanford University … the series for undertaking these challenging topics, while maintaining willingness to support the lead … Information is needed about QI strategies that lead to effective adoption of these preventive interventions … that is safe, effective, patient centered, timely, efficient, and equitable)7 and improvements that lead … However, little is known about which intervention characteristics are likely to lead to success.

399. Treatments for Fecal Incontinence: Current State of the Evidence (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
     July 01, 2016 - issues (impaction, large bowel obstruction) Sacral nerve stimulation Infection, pain, electrode or lead

400. #05 DEPRESSION (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/depression_hi_impact.pdf
     October 01, 2014 - region of the brain. 3 Physicians often perform the device implantation in two separate procedures: lead … support that may come from the…program could provide needed encouragement;” (2) the program could lead