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201. Caffeine | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/caffeine
     Caffeine can interfere with your ability to recognize how drunk you are, which can lead you to drink

202. Noninvasive Treatments for Low Back Pain: A Summary of the Research for Adults (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/back-pain-treatment_consumer.pdf
     November 01, 2016 - Overdose can lead to death. ��Tramadol helps to reduce pain in the short term (up to 4 months). … Vomiting ��Dizziness ��Tiredness ��Sweating �� Itching ��Dry mouth ��Taking opioids often for pain can lead … Overdose can lead to death. ��Opioids can cause life-threatening breathing problems.

203. Enhancing Systematic Review Methods by Incorporating Unpublished Drug Trials | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/unpublished-drug-trials/white-paper
     January 01, 2025 - This can lead to inflated efficacy estimates and underestimated harms or burdens, as unpublished studies

204. Graphical Augmentations to Sample-Size-Based Funnel Plot in Meta-analysis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/grant-manuscripts/graphical-augmentations-abstract
     June 01, 2024 - the four data cells in a 2 × 2 table for the odds ratio), so standard-error-based funnel plots may lead

205. Disposition of Comments Report for CER 226: Labor Dystocia (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-226-labor-dystocia-comments.pdf
     May 14, 2020 - outcomes or aspects of the process (like labor) may affect willingness to be randomized, and may lead … We consistently use Anetheum in this report following the lead of the included publications. … either the likelihood of diagnosis of dystocia (e.g., use of magnesium sulfate in preeclampsia) or lead … concern with amniotomy Although this was not an outcome included— presumably, prolapsed cord would lead … normal and abnormal labor so that cesarean section can be reserved for labors with higher risk to lead

206. PICO Population(s): Breastfeeding infants 6 months or less with ankyloglossia Intervention(s): Frenotomy, Frenectomy, or Frenulotomy Comparator(s): Breastfeeding management without surgical intervention Outcomes(s): Successful exclusive… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/pico-populations-breastfeeding-infants-6-months-or-less-with-ankyloglossia-interventions-frenotomy-frenectomy-or-frenulotomy-comparators-breastfeeding-management-without-surgical-intervention-outcomess-successful-exclusive-b
     November 01, 2017 - and non-exclusive breastfeeding, both have adverse effects on child and maternal health outcomes and lead

207. Adjuvant Treatment for Phenylketonuria: Future Research Needs | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/phenylketonuria-future/research
     December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

208. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
     February 01, 2015 - DEMENTIA INCLUDING ALZHEIMER'S #04 AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 04: Dementia (Including Alzheimer’s Disease) Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road …

209. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
     January 01, 2010 - The nominator indicated interest in whether a genetic testing strategy could lead to improvements in

210. Identifying Priorities for Patient-Centered Outcomes Research for Serious Mental Illness | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/mental-illness-priorities/research
     November 01, 2017 - Structured Abstract The Agency for Healthcare Research and Quality (AHRQ) is the lead Federal agency

211. Methods Guide for Medical Test Reviews (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
     July 01, 2012 - studies evaluating medical tests—systematic error resulting from design, conduct, or reporting that can lead … Therefore, demographic features or disease severity may lead to variations in estimates of test performance … This may lead to biased assessment of the test characteristics. … threshold value for the index test that maximizes the sensitivity and specificity of the test may lead … Inadequacy of reporting, a third common challenge, does not in itself lead to systematic bias but limits

212. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
     February 01, 2015 - Similarly, researchers hypothesize that neurofibrillary tangles adversely affect neuron function and lead … The latter group is lead sponsor on the largest ongoing trial, a phase II/III trial investigating intranasal

213. Vitamin-D-Calcium-Protocol-130611 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/vitamin-d-calcium_research-protocol.pdf
     September 13, 2013 - Inclusion decisions about full-text articles will be reconciled, with disagreements settled by the project lead … Disagreements will be settled by the project lead or co-project lead. … Efficacy and safety data will be abstracted by the statistical analyst and confirmed by the co-project lead … Any questions will be referred to the co-project lead, including questions regarding the assay method

214. Chapter 5: Assessing Risk of Bias as a Domain of Quality in Medical Test Studies | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-bias/methods
     December 01, 2019 - studies evaluating medical tests—systematic error resulting from design, conduct, or reporting that can lead … Therefore, demographic features or disease severity may lead to variations in estimates of test performance … This may lead to biased assessment of the test characteristics. … the threshold value for the index test that maximizes the sensitivity and specificity of the test may lead … Inadequacy of reporting, a third common challenge, does not in itself lead to systematic bias but limits

215. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
     January 01, 2012 - POEM did not lead to any reported serious complications. … Long-term PN can lead to serious side effects such as liver damage, the risk of which increases the … It can lead to complications such as regurgitation, coughing, choking, aspiration pneumonia, esophagitis … estimated mortality rate in infants with SBS is 30%. 53 Long-term parenteral nutrition (PN) can lead … However, experts were divided on whether teduglutide would lead to more significant improvements in

216. Making Healthcare Safer IV: Nursing Staff Shortages | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/nursing-staff-shortages/protocol
     December 01, 2024 - patients, which leads to poor patient outcomes and nurse burnout, or unit capacity is reduced, which could lead … If there is a disagreement between a team member and the AI, the lead investigator will resolve it.

217. Speakerbiosketches Deliberativemethodswebinar1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/speakerbiosketches_deliberativemethodswebinar1.pdf
     May 23, 2012 - Meet Our Presenters Julia Abelson, PhD McMaster University, Professor of Clinical Epidemiology and Biostatistics, Associate Member, Department of Political Science Member, Centre for Health Economics and Policy Analysis (CHEPA) Dr. Abelson's research interests include the design and evaluation of public engage…

218. Disposition of Comments_Comparative Effectiveness Review No. 248: Prehabilitation and Rehabilitation for Major Joint Replacement (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/joint-replacement-disposition-comments.pdf
     November 03, 2021 - programs (i.e., what specific components of rehabilitation and methods in which they are delivered lead

219. Comparing the Effectiveness of Treatment Strategies for Primary Open-Angle Glaucoma | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/glaucoma/abstract
     December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

220. Therapies for Children with Autism Spectrum Disorders—Research Protocol Document | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/autism/research-protocol
     December 01, 2019 - The Methods Lead and content experts will review abstraction forms against the original articles for … the initial review and abstraction was completed, the date it was reviewed and checked by the Methods Lead … spreadsheet will be developed by the Project Coordinator and Administrative Support staff to aid the Content Lead