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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_disposition-comments.pdf
    July 08, 2014 - Treatment may lead to intermediate outcomes, such as changes in level of depression symptoms, or adverse … It is also possible that some issues such as alcohol or substance misuse lead to depression. … Depression during pregnancy is known to lead to harmful prenatal health behaviors such as poor nutrition … Better research may lead to Improved outcomes for pregnant and postpartum women. … Better research may lead to Improved outcomes for pregnant and postpartum women.
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_executive.pdf
    March 01, 2012 - observed for almost all the test-disease combinations; however, the design of case-control studies may lead … .52-54 The selective inclusion of cases with established disease (i.e., JIA or pSLE) is likely to lead … inclusion of healthy controls is expected to decrease the likelihood of false positive test results and lead
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
    December 06, 2010 - of the synovium (a thin layer of tissue lining a joint space) and progressive erosion of bone that lead … will be reviewed for completeness and accuracy by a second senior member of the team, most often the lead
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
    March 01, 2012 - surgery patients at a much higher rate than general surgery or other medical patients, and it can lead … Cardio-vascular Therapeutic Area Lead Ortho-McNeil Janssen Scientific Affairs Payal Desai, … Cardio-vascular Therapeutic Area Lead Ortho-McNeil Janssen Scientific Affairs Payal Desai, … Cardio-vascular Therapeutic Area Lead Ortho-McNeil Janssen Scientific Affairs Payal Desai, … Cardio-vascular Therapeutic Area Lead Ortho-McNeil Janssen Scientific Affairs Payal Desai,
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
    November 03, 2014 - Topic 0613 Tympanostomy Tubes NSD FINAL Tympanostomy Tubes in Children Nomination Summary Document Results of Topic Selection Process & Next Steps § Th…
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
    November 01, 2014 - Furthermore, measuring PK/PD only in the serum may lead to suboptimal antibiotic concentrations at the … In such cases, the antibiotic may not eradicate resistant organisms; this problem may in turn lead … recommendations are based largely on PK/PD studies in healthy volunteers, the recommendations may lead
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diabetes-mobile-devices_research-protocol.pdf
    July 12, 2017 - tools could help patients adhere to diet, exercise, and medication management plans, which could lead
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - This may lead to different outcomes among treatment centers. … However, the mechanism by which these cells lead to cartilage regeneration is unclear.1 MSCs may differentiate … conservative treatment are considerable, and the reported adverse events appear minimal, which could lead … the lower costs and greater symptom relief of PRP over hyaluronic acid injections will eventually lead
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
    January 17, 2017 - Response Peer reviewer #1 Results Another point that is not well discussed is whether T, A or T+A lead … Does a cold versus hot technique lead to less PTH? b. … Does partial versus total tonsillectomy lead to less PTH?
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/acute-pain-protocol-amended.pdf
    June 10, 2018 - Effective treatment of acute pain can minimize the sensitization of pain pathways and tissue damage that lead … The subjective nature of self-report and provider interpretation can lead to a wide range of treatment
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - #06 Developmental Delays ADHD, and Autism AHRQ Healthcare Horizon Scanning System – Potential High-Impact Interventions Report Priority Area 06: Developmental Delays, ADHD, and Autism Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither…
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-topics_methods.pdf
    July 01, 2012 - Methods Guide for Medical Test Reviews Chapter 2 2-1 Chapter 2 Developing the Topic and Structuring Systematic Reviews of Medical Tests: Utility of PICOTS, Analytic Frameworks, Decision Trees, and Other Frameworks David Samson, M.S., Blue Cross and Blue Shield Association Karen M. Schoelles M.D., S.…
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/musculoskeletal-complaints-tests-children_research-protocol.pdf
    September 29, 2010 - follow-up to a negative RF test when clinical signs, such as symmetrical joint pain and inflammation, lead … effective treatment, JIA can progress and cause damage to cartilage, bone and soft tissues, and may lead … diagnosis has become more common20 and rapid introduction of aggressive immunosuppressive treatment may lead
  14. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/14_substance_abuse_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - population, including low adherence to treatment recommendations and medication diversion, which can lead … low patient adherence to treatment recommendations and medication diversion, either of which can lead
  15. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - Bacterial overgrowth in the small intestine may lead to increased gas production, diarrhea, and weight
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/implementation-package-unhealthy-alcohol-use-final.pdf
    September 01, 2018 - often involves the provision of multiple services; the results of a screening test, for example, can lead … reminders, though they can contribute to a program’s sustainment, require tech team staffing and lead … The team included: • Project Lead: experienced primary care clinician and researcher • Clinic Medical … the provision of multiple services; generally, the results of a screening test, for example, can lead
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - If the reference standard does not accurately predict the true status, then it is imperfect and will lead … The complex criteria, as well as the subjective nature of signs and symptoms, lead to differentially … A problem with this method occurs when modeling assumptions are incorrect and lead to biased estimates … It is present in 2 to 4 percent of middle-aged adults and can lead to daytime somnolence, cardiovascular
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
    October 14, 2011 - These programs are based on the premise that PSA testing can lead to early detection of prostate cancer … However, testing total PSA levels to decide which patients should undergo a biopsy has been found to lead … When total PSA testing identifies patients with cancer-positive biopsies, it can again lead to overtreatment

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