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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lysosomal-storage-diseases-therapies_disposition-comments.pdf
    January 01, 2014 - chapter of the report, we included all FDA-submitted pivotal trials, plus prospective reports with larger … chapter of the report, we included all FDA-submitted pivotal trials, plus prospective reports with larger … because the tables primarily included FDA-submitted pivotal trials, plus prospective reports with larger … the tables are comprised of primarily FDA- submitted pivotal trials, plus prospective reports with larger … comprehensive table We included all FDA-submitted pivotal trials, plus prospective reports with larger
  2. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - Data are available from completed pilot studies and larger ongoing studies, but these publications have
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_consumer.pdf
    June 01, 2016 - Or, it may grow as big as a baseball or larger.
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
    August 01, 2012 - revised report also discusses the limitations of available data for different CKD stages within the larger … the benefits and risks of monitoring and treatment in patients with different CKD stages within the larger … revised report also discusses the limitations of available data for different CKD stages within the larger … The report also discusses the limitations of available data for different CKD stages within the larger … The report also discusses the limitations of available data for different CKD stages within the larger
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_disposition-comments.pdf
    May 13, 2014 - when excluding 3 studies that enrolled patients with dual diagnoses, the effect size was slightly larger … We added the following in the results section of KQ 6: “The larger trial (N=627) that the study sample … The authors explained that the lack of an overall treatment effect of naltrexone in the larger trial … But, when there are larger numbers of studies, and a meta-analysis is conducted, the overall effect … For our data analyses, we used data from Volpicelli 1995 to use the larger, more complete sample and
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
    January 01, 2023 - In general, longer followup periods, study expansion to multiple sites, and the recruitment of larger … Benefits are smaller in sham compared with usual care controlled trials and larger in trials of patients
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_disposition-comments.pdf
    April 01, 2013 - Updated results from the larger trial, the ERSPC trial, were published in NEJM, March 15 2012, showing … Deras provided a slightly larger sample size with a clear presentation of data for three of the five … The Haese dataset was very slightly larger, but all repeat status, central measures, positive rate, … Groskopf/ Gen-Probe # 10 Results Data from larger, multi-center studies have more weight and should … The Haese dataset was very slightly larger, but all repeat status, central measures, Source: http:
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
    November 06, 2012 - that the effects of high- resistance strength training (>60 percent of one repetition maximum) appear larger … While in few outcome comparisons the no PT involvement groups had a larger effect size, in general … we found effect sizes with PT involvement are larger than that without PT involvement by 0.1 standardized … While the no PT involvement groups had a larger effect size in few outcome comparisons, in general … we found effect sizes with PT involvement are larger than that without PT involvement by 0.1 standardized
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment-future_research.pdf
    September 01, 2012 - Studies with larger sample sizes, including multicenter trials; 3. … Additionally, it was noted that all study designs should account for the need for larger sample sizes … Studies with larger sample sizes, including multicenter trials; 3. … Additionally, it was noted that all study designs should account for the need for larger sample sizes … apply-for- funding/ • Project Grants: • Every two years from 2013, we will invite applications for larger
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
    January 01, 2010 - When RCTs report only an intermediate outcome, for example, larger, longer, well-designed observational … population of interest, particularly if that population is a subgroup or a vulnerable section of a larger
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-applicability_methods.pdf
    July 01, 2012 - Lack of specificity in key questions can result in reviews of larger scope than necessary, failure to … Alternatively, the larger literature could be reviewed with careful attention to biologic and health
  12. effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
    January 01, 2010 - When RCTs report only an intermediate outcome, for example, larger, longer, well-designed observational … population of interest, particularly if that population is a subgroup or a vulnerable section of a larger
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_executive.pdf
    October 01, 2012 - have found that these interventions are often not used sufficiently in practice.1,2 As part of a larger … Similar findings were noted when including only larger studies (100-200 patients); 5 of these 11 studies
  14. effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
    October 30, 2012 - are used as compared with individual outcomes, since by grouping numerous types of events into a larger … primary interest, and if they are measured on all patients, the number of outcomes for analysis may be larger … Computer adaptive testing is based on IRT methods of scaling items and drawing subsets of items from a larger … This problem can present as a “ceiling” effect, where a larger proportion of the sample reports no
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_disposition-comments.pdf
    October 01, 2012 - I think the larger providers would use the paper and appreciate it, but if the goal is to penetrate … with very advanced or serious disease (only 93 studies were included in this review from a much larger … 37(3):373-386. 10.1016/j.jpainsymman.2008.03.020 We have clarified that this report is part of a larger … We have added in more detailed information on these studies for these larger sections (continuity,
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
    January 01, 2010 - Pattern of a larger effect with greater exposure (dose, duration, adherence) either across or within … Dose-Response Association This association, either across or within studies, refers to a pattern of a larger … Had such “effect-weakening” confounders not been present, the observed effect would have been even larger
  17. effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
    January 01, 2013 - Additional Domains: Dose-Response Association Pattern of a larger effect with greater exposure (dose … Dose-Response Association This association, either across or within studies, refers to a pattern of a larger … Had such “effect-weakening” confounders not been present, the observed effect would have been even larger
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
    March 26, 2013 - report probabilities that the difference (in the odds ratio scale) between pairs of treatments is larger … statistical tests to evaluate differences in the effect sizes between more precise (larger … can lead to a statistically significant result, including “true” heterogeneity between smaller and larger
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
    May 01, 2025 - National Cancer Institute is sponsoring the Vanguard Feasibility trial to gather information for a future larger
  20. effectivehealthcare.ahrq.gov/health-topics/prostate-diseases

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