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  1. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-medications-for-risk-reduction
    September 03, 2019 - Trials included large numbers of women, ranging in size from 1884 41 to 19,747, 49 primarily from North … , 76 and exemestane. 44 , 77 For tamoxifen, information on adverse effects was confined to the 5 large … the meta-analyses of tamoxifen trials. 41 For raloxifene, adverse effects were reported from the 2 large … studies contribute little to the evaluation of harms because they involve few women relative to the large … Risk prediction for estrogen receptor–specific breast cancers in two large prospective cohorts.
  2. www.uspreventiveservicestaskforce.org/uspstf/recommendation/diabetes-mellitus-type-2-in-adults-screening-2003
    February 04, 2003 - considered for patients who have impaired fasting glucose or impaired glucose tolerance, since several large … with FPG, the 2‐hour PG as a screening test leads to more individuals being diagnosed as diabetic. 4 Large … Three large trials in the United States, Finland, and China have demonstrated that intensive programs … the conventional treatment arm; however, no difference in visual outcomes was detected. 25 , 26 One large
  3. www.uspreventiveservicestaskforce.org/uspstf/recommendation/suicide-risk-in-adolescents-adults-and-older-adults-screening
    May 20, 2014 - A large proportion of Americans have a risk factor for suicide; however, only a small proportion will … A large proportion of Americans have 1 of these risk factors; however, only a small proportion will attempt … The possibility of incorporating technology into large-scale screening studies should also be explored … A single large trial of older primary care patients reported a 20% reduction in the relative risk for
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/fbQmoAPKeBekmJ7aqmALe5
    June 01, 2014 - sitivity and specificity of the MMSE probably vary depend- ing on the patient’s age and education level, a large … Data from large population-based surveys indicate that the prev- alence of dementia in the United States … Prevalence varies by race; prevalence in adults aged 71 years or older in 1 large study was 21.3% for … becomes available, the magnitude or direction of the observed effect could change, and this change may be large
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/9Tse2TwVFQgYb-aNCq4Ngv
    September 04, 2018 - for syphilis in pregnancy (KQ1), randomized or non- randomized controlled intervention studies and large … Four large, fair-quality retrospective studies evaluated the proportion of false- positive results using … nonspecific antibody (as may occur in secondary syphilis) produces a false-negative result attributable to a large … Incidence and risk factors for the prozone phenomenon in serologic testing for syphilis in a large cohort
  6. www.uspreventiveservicestaskforce.org/uspstf/recommendation/dental-caries-in-preschool-children-screening-2004
    April 15, 2004 - dental fluorosis, although the fluorosis is very mild (as classified by Dean's Fluorosis Index) in the large … The number of risk indicators for dental caries is large, 14 , 15 and subsets of these have been suggested
  7. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/dental-caries-in-preschool-children-screening-2004
    April 15, 2004 - dental fluorosis, although the fluorosis is very mild (as classified by Dean's Fluorosis Index) in the large … The number of risk indicators for dental caries is large, 14 , 15 and subsets of these have been suggested
  8. www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-screening-2009
    February 15, 2009 - A large systematic review analyzed the evidence on diagnostic accuracy of primary care physicians and … A large evaluation study of the American Academy of Dermatology's Skin Cancer Screening Program 5 found
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/za7BqXMwT8BMz4Z_ygrvKm
    May 01, 2004 - Two large cohort studies using transvaginal ultrasound screening reported that 59% to 65% of ovarian … Estrogen replacement therapy and ovarian cancer mortality in a large prospective study of US women.
  10. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/vision-in-children-ages-6-months-to-5-years-screening
    September 05, 2017 - qualitatively evaluating LRs, positive LRs indicated a minimal (>1-2), small (>2-5), moderate (>5-10), or large … Negative LRs indicated a minimal (0.5 to <1), small (0.2 to <0.5), moderate (0.1 to <0.2), or large ( … between 0.10 logMAR (about 1 line on the Snellen chart) and 0.15 logMAR (between 1 and 2 lines). 40-42 Large … , 91 Overall, most studies found moderate positive LRs and small negative LRs, although some found large … A large (n = 102,508) retrospective study from a statewide photoscreening program found that 19.5% (174
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/aSTzfuKHZtT8_PjfJjuck5
    March 01, 2013 - becomes available, the magnitude or direction of the observed effect could change, and this change may be large … In a large study in 1 health care system, the prevalence of abuse was 7.9% in the preceding year and … A large cluster randomized, controlled trial of the ef- fectiveness of screening for IPV included 6743 … Of the latter 3, 1 was a large trial of 6743 women that evaluated screening versus no screening and found
  12. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/perinatal-depression-preventive-interventions
    August 11, 2016 - Systematic reviews; meta-analyses; randomized, controlled trials; controlled clinical trials; and large
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/_ZPNC3vqdS3R-ggXro6UAM
    April 05, 2016 - detection and treatment, the opportunity cost associated with screening asymp- tomatic persons may be large … becomes available, the magnitude or direction of the observed effect could change, and this change may be large … This recom- mendation was based on the conclusion that screening for COPD had no net benefit and large
  14. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cognitive-impairment-older-adults
    June 12, 2025 - studies KQ 4: Randomized, controlled trials KQ 5: Randomized, controlled trials included in KQ4; large
  15. www.uspreventiveservicestaskforce.org/uspstf/recommendation/bladder-cancer-adults-screening-1996
    January 01, 1996 - studies, 46-55% of men with asymptomatic hematuria had no identifiable source of bleeding. 17-19 Two large
  16. www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening-2003
    January 07, 2003 - There are at least eight studies evaluating HPV testing in large populations underway or recently completed … Two large series documenting the low risk of cytologic abnormality after hysterectomy have been published … Data from a large screening program in the United States indicate that a longer interval (3 years vs
  17. www.uspreventiveservicestaskforce.org/uspstf/document/update-on-the-methods-of-the-us-preventive-services-task-force-estimating-certainty-and-magnitude-of-net-bene%EF%AC%81t/carotid-artery-stenosis-screening-december-2007
    December 15, 2007 - For screening topics, this standard could be met by a large randomized, controlled trial (RCT) in a representative … How large are the studies? (i.e., what is the precision of the evidence?) … becomes available, the magnitude or direction of the observed effect could change, and this change may be large
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/4zmYnqJXLv8g4LzLrrDDrm
    December 01, 2014 - One large trial was conducted in the United States, and another large, multinational trial was coordinated … Two large RCTs, the Maternal-Fetal Medicine Units (MFMU) trial and the Collaborative Low-dose Aspirin … becomes available, the magnitude or direction of the observed effect could change, and this change may be large
  19. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cardiovascular/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - The fourth large trial (WHS) showed an MI benefit in the older age group but not overall. … This good-quality trial of 100 mg of aspirin every other day was conducted in a large sample of generally … These trials showed no statistical difference in aspirin's effect by diabetes status, including the large … A large ongoing trial of 19,000 participants aged 70 years or older may confirm this finding. 50 We … Two large RCTs (together enrolling >20,000 patients with diabetes) 56 , 57 that are in progress may
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/dvcAbDQWejyK38oxF8qgka
    November 01, 2012 - Large, fair-quality cohort studies also consistently found that ART initiation at CD4 counts of 0.350 … Two other large cohort studies found that ART initiation at CD4 counts greater than 0.500 � 109 cells … Longer-Term Harms Associated With ART The 2005 USPSTF review included results from the large, ongoing … 1 large cohort study found that longer duration of exposure to some protease inhibitors was associated … Five large observational studies also found that initiating ART at CD4 counts between 0.350 and 0.500

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