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  1. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
    September 28, 2021 - In the few large studies with these and other maternal health outcomes, risk estimates were too imprecise … Longer-term follow-up from 1 large multicenter trial 36 was also reassuring, finding no difference in … Second, only 2 of the included studies implemented dosages of 150 mg/d, and one of them (ASPRE, a new large … risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large … RR, 1.15 [95% CI, 0.76-1.72]; I 2 = 25%; 13 studies) was also null Longer-term follow-up from 1 large
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/B73a4kJhxeaYyXK6gozbbY
    May 24, 2022 - worse than 20/60 at 3- to 5-year follow-up (relative risk [RR], 1.07 [95% CI, 0.84-1.36]).23 Another large … clinically important difference (4 to 6 points).63 Antioxidant Vitamins and Minerals for Dry AMD The large … Besides AREDS, the systematic review included the large (n = 4203) AREDS2 trial,51,60 which evaluated … minerals for slowing progression of disease or improv- ing visual acuity remains largely based on the large … evi- dence on effectiveness of treatment for dry AMD relied heavily on results of a single trial—the large
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/EGPJ5VSbLv4_cDB7fQBmGR
    May 01, 2014 - A large proportion of Americans have a risk factor for suicide; however, only a small proportion will … A large pro- portion of Americans have 1 of these risk factors; however, only a small proportion will … The possibility of incorporating technology into large-scale screening studies should also be explored … A single large trial of older primary care patients reported a 20% reduction in the relative risk for … becomes available, the magnitude or direction of the observed effect could change, and this change may be large
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/kBouKdKBx6XdvyT6Mej8w4
    September 01, 2023 - role of autofluorescence imaging in determining biopsy of oral potentially malignant disorders: A large
  5. www.uspreventiveservicestaskforce.org/uspstf/recommendation/blood-pressure-in-adults-hypertension-screening-2007
    December 15, 2007 - For those who consume large amounts of alcohol (>20 drinks per week), studies have shown that reduced … becomes available, the magnitude or direction of the observed effect could change, and this change may be large
  6. www.uspreventiveservicestaskforce.org/uspstf/recommendation/chronic-obstructive-pulmonary-disease-screening
    May 10, 2022 - One large randomized clinical trial (SUMMIT; n = 16,590) in persons with or at risk for cardiovascular … However, large observational studies in screen-relevant populations suggest possible harms for LAMA or … Given that the opportunity costs associated with screening asymptomatic persons may be large, the USPSTF
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/BhnZRA--TRpXdg9_tYmZ_M
    April 05, 2016 - COPD using spirometry (grade D).10 The USPSTF concluded that this method had no net benefit and had large … postbronchodi- lator ratio of FEV1 to forced vital capacity (FVC) of less than 0.70.7 For KQs 4 and 6, RCTs, large … treatment of COPD (KQ8), the data were limited to what was reported in the efficacy trials included in KQ7, large … studies of PEF evaluated the largest number of patients (n = 23 098).37,38 However, these were based on large … LABAs One post hoc subanalysis of a large 4-group RCT and 1 post hoc pooled subanalysis from 3 other
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/mggnaKHr496c8QCgHe9-tm
    May 01, 2021 - . • Given that the opportunity costs associated with screening asymptomatic persons may be large, the … One large randomized clinical trial (SUMMIT; n = 16 590) in persons with or at risk for cardiovascular … How- ever, large observational studies in screen-relevant populations sug- gest possible harms for LAMA
  9. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
    November 24, 2020 - The USPSTF recognizes that there are large disparities in access to resources that support a healthy … Despite the large number of included trials reviewed by the USPSTF, there were few replication studies … Large replication studies of interventions showing reductions in CVD events are urgently needed.
  10. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary10/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication-2009
    March 15, 2009 - The results of this study are difficult to interpret because a large number of participants had crossed … prevention of myocardial infarction has been called into question after the publication of a recent large … reliability of test assessed, has few or handles indeterminate results in a reasonable manner, includes large … reliability of test assessed, has few or handles indeterminate results in a reasonable manner, includes large
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/t6yV6ZMHngeWgmTsoMMefM
    March 01, 2009 - The results of this study are difficult to interpret because a large number of participants had crossed … prevention of myocardial infarction has been called into question after the publication of a recent large … reliability of test assessed, has few or handles indeterminate results in a reasonable manner, includes large … reliability of test assessed, has few or handles indeterminate results in a reasonable manner, includes large
  12. www.uspreventiveservicestaskforce.org/uspstf/recommendation/family-violence-screening-interventions-1996
    January 01, 1996 - this problem. 30 , 33 The routine patient interview often fails to detect abuse in adult patients, in large … The large majority of abuse victims favored routine questions about abuse, and half indicated that they … A large controlled study is under way to examine whether an integrated program to improve detection and … leads to better clinical outcomes. 68 Effective interventions for elder abuse may also be limited, in large
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/hWPZYvUZJXUQghbFtSDC42
    August 01, 2011 - becomes available, the magnitude or direction of the observed effect could change, and this change may be large … evalu- ating these harms could include conducting observational studies based on patient registries or large … One large, uncontrolled observational study of 2821 patients (8) reported bleeding and perforation in
  14. www.uspreventiveservicestaskforce.org/uspstf/recommendation/visual-impairment-in-children-ages-1-5-screening-2011
    January 15, 2011 - interfere with normal binocular vision, such as strabismus (ocular misalignment), anisometropia (a large … One large, statewide screening study of the Medical Technologies photoscreener found 94% testability … Six of 7 studies reported false-positive rates of >70% in low-prevalence populations. 1 One large study
  15. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review79/ovarian-cancer-screening-2004
    May 15, 2004 - ovarian volume is 3 or more multiples of the median for postmenopausal women or if a complicated or largeLarge RCTs of screening with mortality outcomes are currently in progress and will provide more definitive … Estrogen replacement therapy and ovarian cancer mortality in a large prospective study of US women.
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RyyuauSH7K-HPXD6tgx2xu
    July 01, 2008 - becomes available, the magnitude or direction of the observed effect could change, and this change may be large … We give priority to fast-tracking large clinical trials with clinical outcomes.
  17. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cognitive-impairment-older-adults
    March 06, 2025 - studies KQ4: Randomized, controlled trials KQ 5: Randomized, controlled trials included in KQ4; large
  18. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
    January 19, 2021 - product and there are persistent differences in rates of smoking by age, sex, and race/ethnicity. 1 A large … Data Synthesis and Analysis Given the large number of reviews that met eligibility criteria and the … Additionally, 5 large observational studies (n = 1,293,379) (reported in 6 publications) 110-115 were … use–associated lung injury. 118 Furthermore, there is lack of long-term epidemiologic studies and large … However, given the large number of trials in these reviews, this does not suggest the results would be
  19. www.uspreventiveservicestaskforce.org/uspstf/recommendation/human-immunodeficiency-virus-hiv-infection-screening-2013
    April 15, 2013 - generalizability of the findings to the U.S. primary care population and may partially account for the large … Data from a third large randomized trial conducted primarily in Europe and North America (the SMART [ … The 2005 USPSTF review included results from the large, ongoing DAD (Data Collection on Adverse Events
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZR66ep5ABbQCUQy7KTDETn
    July 01, 2014 - For example, screening is probably appro- priate in settings that treat a large proportion of persons … The largest trial, the CALM (Cirrhosis Asian Lamivu- dine Multicentre) study, had a large effect on the … becomes available, the magnitude or direction of the observed effect could change, and this change may be large

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