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srdrplus.ahrq.gov/published_projects?page=16
July 29, 2022 - Magnitude of benefit was categorized into no effect, or small, moderate, and large effects. … There was a large increased risk of dizziness and sedation and a moderate increased risk of nausea (dizziness … was associated with a moderate improvement in pain severity, a moderate increase in sedation, and a large … We found moderate SOE for a large increased risk of dizziness (2 RCTs, 32% vs. 11%, RR 2.74, 95% CI 1.47 … Extracted whole-plant, high-THC to CBD (oral) was associated with a large increased risk of study withdrawal
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srdrplus.ahrq.gov/published_projects?page=6
July 24, 2023 - accuracy studies were used for smaller evidence bases, and existing systematic reviews (ESR) were used for large … the patient health questionnaire (PHQ)-2 followed by the full PHQ-9 if the PHQ-2 is positive), and a large … A large body of both primary and ESR evidence supports the benefit of treatment for anxiety. … instrument; and suicide prevention studies did not demonstrate an improvement over usual care, and one large
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srdrplus.ahrq.gov/published_projects?page=17
November 22, 2023 - A large body of evidence is available to evaluate adverse events following vaccination. … Across this large body of research, we found no new evidence of increased risk since the prior 2014 report … Effects were classified as small, moderate, or large using previously defined criteria.
Results. … pain and function in older patients with vertebral compression fracture at up to 1 month (moderate to large … trials) is probably more effective for pain and function versus sham at 1 and 3 months (moderate to large
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srdrplus.ahrq.gov/published_projects?page=43
June 27, 2021 - The population groups highlighted in this review are large and diverse. … Large segments of vulnerable or disadvantaged populations, such as children with disabilities, people … There are many gaps in the literature; many large subpopulations are not represented. … Outcome reporting and intervention effect sizes varied, and a large placebo response was often observed … Effect sizes vary, and a large placebo response is sometimes observed.
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srdrplus.ahrq.gov/published_projects?page=9
January 17, 2023 - Two large observational studies in a screen-relevant population demonstrated an association of the initiation … Selection: We dually reviewed the literature and included randomized, placebo-controlled trials and large … Data Synthesis: Twenty fair- or good-quality trials and three large controlled cohort studies met eligibility
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srdrplus.ahrq.gov/published_projects?page=7
June 13, 2023 - For treatment of LTBI, a large (N=27,830) good-quality randomized, controlled trial (RCT) found a relative … For harms, a large (N=27,830) good-quality RCT reported an RR for hepatotoxicity of 4.59 (95% CI, 2.03 … For treatment of LTBI, a large (N=27,830) good-quality randomized, controlled trial (RCT) found a relative … For harms, a large (N=27,830) good-quality RCT reported an RR for hepatotoxicity of 4.59 (95% CI, 2.03
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srdrplus.ahrq.gov/published_projects?page=50
June 23, 2021 - exclusion criteria, we included existing systematic reviews, randomized controlled clinical trials, and large … The Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT), a large (n=1,583), high- quality, National
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srdrplus.ahrq.gov/published_projects?page=18
October 06, 2021 - We included randomized controlled trials (RCTs) and large observational studies (for safety assessments … availability of services), and payers (e.g., network adequacy); we identified 47 studies that assessed a large
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srdrplus.ahrq.gov/published_projects?page=8
May 30, 2023 - For treatment of LTBI, a large (N=27,830) good-quality randomized, controlled trial (RCT) found a relative … For harms, a large (N=27,830) good-quality RCT reported an RR for hepatotoxicity of 4.59 (95% CI, 2.03 … Although the evidence map shows a large volume of studies evaluating nutrition interventions and outcomes … Regarding all-cause mortality, the same pattern was observed over three large nonrandomized studies.
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srdrplus.ahrq.gov/published_projects?page=53
March 03, 2021 - However, a clinical registry that can provide meaningful data on the long-term safety requires a large … For generalized anxiety disorder, pooled analysis of three large trials showed that quetiapine was associated
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srdrplus.ahrq.gov/published_projects?page=48
October 31, 2022 - We focused on patient subgroups rather than overall treatment effects to complement a large systematic
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srdrplus.ahrq.gov/published_projects?page=11
October 25, 2022 - Results were primarily driven by the large (n=3,640) Age-Related Eye Disease Study (AREDS). … Results were primarily driven by the large (n=3,640) Age-Related Eye Disease Study (AREDS). … controlled trials (RCTs) on the benefits and harms of statin therapy versus placebo or no statin and large … 1 new trial and 2 older trials that reported results for the primary prevention population) and one large
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srdrplus.ahrq.gov/published_projects?page=20
June 27, 2021 - We derived thresholds defining “small”, “moderate” and “large” effect, summarize key findings from prior … Large, long-term RCTs in PSA-detected and MRI staged CLPC are needed.
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srdrplus.ahrq.gov/published_projects?page=55
March 01, 2021 - Large prospective cohort studies using standard NAFLD diagnosis are needed to examine the complex relationships
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srdrplus.ahrq.gov/published_projects?page=47
June 23, 2021 - We also included randomized trials that compared different injection techniques and large (sample sizes
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srdrplus.ahrq.gov/published_projects?page=45
June 23, 2021 - A large body of literature evidence exists on low-calorie sweeteners yet the health effects of LCS beyond
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srdrplus.ahrq.gov/published_projects?page=24
October 31, 2022 - Observing the effects of hypoglycemic drugs requires studies with large samples and long term observation
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srdrplus.ahrq.gov/published_projects?page=28
June 27, 2021 - discontinuation of alendronate after 5 years reduced risk of incident clinical vertebral fractures in one large
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srdrplus.ahrq.gov/published_projects?page=30
June 27, 2021 - clinical significance, with values that were less than the minimally important difference, but still large
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srdrplus.ahrq.gov/published_projects?page=25
June 27, 2021 - A large observational study also found initiation of ART in persons in high-resource settings with CD4