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Showing results for "large".

41. Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update - Evidence Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/noninvasive-nonpharm-pain-summary.pdf
    April 01, 2020 - with a 0 to 10 scale for pain or function as small (0.5 to 1 point), moderate (>1 to 2 points), or large … ; Intermediate-Term: ≥6 to <12 months; Long-Term: ≥12 months Effect Size: none, small, moderate, or large … ; Intermediate-Term: ≥6 to <12 months; Long-Term: ≥12 months Effect Size: none, small, moderate, or large … ; Intermediate-Term: ≥6 to <12 months; Long-Term: ≥12 months Effect Size: none, small, moderate, or large … ; Intermediate-Term: ≥6 to <12 months; Long-Term: ≥12 months Effect Size: none, small, moderate, or large

42. Assessing Applicability (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
    January 01, 2009 - Studies conducted in large academic medical centers in major cities might not be as applicable to rural … Unfortunately, these clinical trials, by and large, compared bypass surgery versus angioplasty with or … In contemporary practice, however, a large subset of patients undergo angioplasty with a drug-eluting … Finally, the settings for the studies are large tertiary medical centers, which may overestimate the … These trials were conducted in select, large, tertiary care medical centers and may not be applicable

43. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
    September 01, 2009 - raloxifene, and tibolone for the primary prevention of breast cancer, mortality, and fractures: • Eight large … Strength of Evidence Symbols +++ High: Consistent results from numerous (>5) or large definitive trials … raloxifene, and tibolone when used for primary prevention of breast cancer: • In addition to the 8 large … endometrial cancer in clinical trials but was associated with more cases of endometrial cancer in a large … Strength of Evidence Symbols +++ High: Consistent results from numerous (>5) or large definitive trials

44. Future Research Needs for Treatment of Obstructive Sleep Apnea (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
    February 01, 2012 - Moderate resources may be necessary to recruit and follow a large cohort over a long timeframe. … In summary, the online Web site discussion of numerous topics by a large stakeholder panel was only … When considering clinical outcomes, there is a potential for a large loss in followup. … However, there is potential for large data loss due to long-term followup. … Represents a significant disease burden; large proportion or priority population 2b.

45. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 2 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
    March 01, 2022 - There may be a large increased risk of dizziness and sedation, and a moderate increased risk of nausea … Synthetic THC is probably associated with a large increased risk of dizziness. … • Extracted whole-plant high THC to CBD ratio products may be associated with large increases in … Magnitude of benefit was categorized into no effect or small, moderate, and large effects. … Large effects are defined as greater than moderate.

46. Disposition of Comments: Comparative Effectiveness Review No. 238 Cervical Ripening in the Outpatient Setting (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
    March 22, 2021 - We agree that more high quality, large, RCTs are needed. … Discussion sections don’t often get much attention in a large report like this, but as is often the … agree that the evidence is not strong, and we do recommend future RCTs, in diverse populations, with large … Also, a large evidence review like this on a contemporary trend reveals that the evidence to fully

47. White Paper_Machine Learning Tools To (Semi-)Automate Evidence Synthesis: A Rapid Review and Evidence Map (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/machine-learning-tools-white-paper.pdf
    December 01, 2024 - Recent advances in NLP have yielded generative large language models that are pretrained on textual … data from large amounts of text (usually from the Internet) to predict which words generally follow … Automated Paper Screening for Clinical Reviews Using Large Language Models: Data Analysis Study. … Data extraction for evidence synthesis using a large language model: A proof-of-concept study. … How good are large language models for automated data extraction from randomized trials?

48. Nonpharmacologic Treatment for Maternal Mental Health Conditions (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-pregnant-protocol.pdf
    August 24, 2023 - Due to time and resource restrictions, for topics with large bodies of evidence, we plan to restrict … We will also include comparisons with at least one large (N≥100 per group), low or moderate risk … Also addition of full review of large, low or moderate risk of bias studies in the full report. … If we determine these large studies are at high risk of bias, we will explain why. … For studies meeting criteria for full data synthesis (and for other large studies [N≥100 per group

49. Assessing Applicability (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
    January 01, 2009 - Studies conducted in large academic medical centers in major cities might not be as applicable to rural … Unfortunately, these clinical trials, by and large, compared bypass surgery versus angioplasty with or … In contemporary practice, however, a large subset of patients undergo angioplasty with a drug-eluting … Finally, the settings for the studies are large tertiary medical centers, which may overestimate the … These trials were conducted in select, large, tertiary care medical centers and may not be applicable

50. Treatments for Fecal Incontinence: A Review of the Research for Adults (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_consumer.pdf
    July 01, 2016 - Understanding Your Condition Stomach Small Intestine Large … Any food that cannot be digested moves into your large intestine as waste. … The last part of the large intestine is called the rectum. … As waste is made, it travels through your large intestine and rectum.

51. Monitoring-Programs-Rapid-Research-Appendix-C (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-rapid-research-appendix-c.xlsx
    May 31, 2025 - medications to supplement wholesaler allocations 1) Increased patient volume and demand 2) Remote work for a large … Cloud-based enterprise resource purchasing system to consolidate purchasing systems into one platform across large … supplies from international manufacturers NR Snowdon, 2018b Snowdon, 2018c Case report United States Large

52. S9 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s9.pdf
    October 01, 2007 - program also introduces the potential for a comprehensive administrative prescription drug database for a large … Another promising feature of Medicare Part D data relates to the large numbers of Medicare beneficiaries … who are currently enrolled in Part D, indicating a large population for which data are available. … analyses that could assess the impacts of prescription drug use on health care costs and quality for a large … applications of these data (including the ability to analyze patterns of prescription drug utilization over a large

53. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
    October 01, 2010 - Standardized mean differences of 0.3, 0.5 and 0.8 are suggested corresponding to small, medium, and large … Investigators can choose to combine the large studies if they are well conducted with good quality … between treatment and control group sizes within trials and treatment effects are not exceptionally large … there is no real difference among effect sizes, particularly when the power to detect variation is large … A qualitative indirect comparison may be useful to judge comparable effectiveness when there is a large

54. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
    October 01, 2010 - Standardized mean differences of 0.3, 0.5 and 0.8 are suggested corresponding to small, medium, and large … Investigators can choose to combine the large studies if they are well conducted with good quality … between treatment and control group sizes within trials and treatment effects are not exceptionally large … there is no real difference among effect sizes, particularly when the power to detect variation is large … A qualitative indirect comparison may be useful to judge comparable effectiveness when there is a large

55. Asthma-Provider-Adherence Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-provider-adherence_executive.pdf
    May 01, 2013 - No conclusion; One study reported a large reduction, but study quality was low. … The magnitude of effect is large: 2%–34% in pre-post studies; 2%–17% in RCTs. … The magnitude of effect is large: 14%–84%. … Magnitude of effect is large in pre-post studies (41%–54%) and small in RCTs (1%–7%). … Improved asthma outcomes using a coordinated care approach in a large medical group.

56. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
    March 29, 2011 - What is the comparative effectiveness of large neutral amino acids (LNAAs) with dietary intervention … Large neutral amino acids in the treatment of phenylketonuria (PKU). … Large neutral amino acids supplementation in phenylketonuric patients. … Large neutral amino acids in the treatment of phenylketonuria (PKU). … Large neutral amino acids supplementation in phenylketonuric patients.

57. Ch 3-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
    September 21, 2012 - Pragmatic trials are large and simple experiments on treatments, with broad eligibility criteria, from … sample size required for detecting ATE of a particular size, a sample size roughly four times as large … of the same magnitude as ATE for a 50:50 subgroup split; a sample size approximately 16 times as large … the potential for subgroup analyses (and implied HTE) to lead to erroneous inferences came from a large … be viewed as an extreme version of subgroup analysis, where individuals are cross-classified by a large

58. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 3 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
    May 01, 2022 - There may be a large increased risk of dizziness and sedation, and a moderate increased risk of nausea … Synthetic THC is probably associated with a large increased risk of dizziness. … • Extracted whole-plant high THC to CBD ratio products may be associated with large increases in … Magnitude of benefit was categorized into no effect or small, moderate, and large effects. … Large effects are defined as greater than moderate.

59. Disposition of Comments_Comparative Effectiveness Review No. 245: Breast Reconstruction After Mastectomy (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-disposition-comments.pdf
    October 01, 2021 - risks of reconstruction with breast implants barely mentions breast implant associated anaplastic large … for this SR did not address the risk of new neoplasms, in particular implant- associated anaplastic large … reconstruction with breast implants, the draft only mentions breast implant associated anaplastic large … for this SR did not address the risk of new neoplasms, in particular implant- associated anaplastic large

60. Stroke-Atrial-Fibrillation Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
    August 01, 2013 - Since 2007, three large trials comparing novel anticoagulants with VKAs have been completed, with a … The evolution of newer anticoagulation agents, like those studied in the large trials above, as well … rating on the findings from the large RCTs and then increased or decreased the strength-ofevidence … This conclusion is based on one large good-quality trial involving 7,554 patients that showed lower … • Based on one large retrospective good-quality study involving 54,636 patients, warfarin reduces