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Showing results for "large".

361. Disposition of Comments for CER 181 Mental Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-children_disposition-comments.pdf
     December 19, 2016 - We upgraded the evidence by one level for factors such as large magnitude of effect’. … Peer Reviewer 5 Results A large detailed table that lists the studies and has: title, citation, dates … can then use to make funding priorities Peer Reviewer 2 Discussion/ Conclusion These are often large … criteria with including more studies but not being able to make any additional conclusions from the large … of the interventions reviewed as being meaningless because of the small number of studies and the large

362. Comparative Effectiveness and Safety of Analgesics for Osteoarthritis—An Update of the 2006 Report. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
     October 01, 2011 - Large observational studies that have stratified subjects by age have not showed a consistent in relative … The authors have done a good job of summarizing a large body of evidence in the results in Table A. … ES-9 –line 7-14 “The systematic review included the pivotal, large, long-term CLASS study, in which … We revised to state (page 17, line 14): “The systematic review included the pivotal, large, long-term … observational studies comparing celecoxib versus naproxen (p 17 line 40): “Three large observational

363. Renal-Cancer Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
     April 20, 2015 - ratio for percutaneous renal sampling or nephron-sparing surgeries than the population of men with large … Treatments such as robotic partial nephrectomy were still in their infancy, and the large clinical data … rates are between 5-10%, substantial differences between the N of two arms, or when effect size is large … 2002 American Joint Committee on cancer primary tumor classification for renal cell carcinoma using a large … Pierorazio, P.M., et al., Laparoscopic radical nephrectomy for large renal masses: critical assessment

364. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
     November 01, 2013 - increasing dose-response associations, plausible confounding that decreases the observed effect, and large … EPC and GRADE Approaches to Evaluating Evidence The EPCs’ strength of evidence approach is based in large … This additional domain should be considered when the effect size is particularly large. … This choice may be particularly preferable when the evidence includes a large number of findings that … Timing of Reporting Bias Assessments A body of evidence that includes many studies of a large number

365. Transcript Deliberativemethodswebinar (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/transcript_deliberativemethodswebinar.pdf
     April 19, 2012 - organizations where a major decision is being taken that’s high profile that will effect a very large … As I’ve stated earlier, deliberation can occur over a very large or very small scale, again, depending … Whether you’re going large or small-scale, you know, again, some things to keep in mind: Making sure … So often in a large deliberative forum you may 32 break off into smaller groups to take on some … the larger group, so that you’re not simply doing the same thing over in the small group and the large

366. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_executive.pdf
     March 01, 2017 - are rarely possible, due to the extended study length required (i.e., >10 years) or the extremely large … including: 1) Meaningful investigation of dementia-onset requires either a long followup period or a large … Conclusion At present, there is not sufficient strength of evidence to justify large-scale investing

367. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline_executive.pdf
     March 01, 2017 - are rarely possible, due to the extended study length required (i.e., >10 years) or the extremely large … including: 1) Meaningful investigation of dementia-onset requires either a long followup period or a large … Conclusion At present, there is not sufficient strength of evidence to justify large-scale investing

368. Systematic Review on Nonopioid Pharmacologic Treatments for Chronic Pain: Surveillance Report 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
     April 01, 2022 - sample sizes of new studies eligible for meta-analysis (meta-analysis performed if new evidence was large … increase in cognitive AEs • SOE: Low based on 8 RCTs Large increase in dizziness, peripheral edema … short- term Topical capsaicin resulted in moderate increase in application site erythema and a large … Dronabinol associated with no increase in SAEs, WAEs, or nausea; oral THC/CBD associated with large … chronic pain after whiplash injury in at-risk individuals: results of a feasibility study for a large

369. Evidence Summary_Comparative Effectiveness Review No. 246_Management of High-Need High-Cost Patients: A "Best Fit" Framework Synthesis, Realist Review, and Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hnhc-evidence-summary.pdf
     October 01, 2021 - Financial success of these models can depend, in large part, on their effectiveness in addressing care

370. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
     October 01, 2010 - future research, including the elderly, those with low EF or large LAD, and people with multiple comorbidities … specifically in patients with heart failure as discussed previously.(4,5) Both of these studies showed quite large … Both studies reported large and statistically significant improvements in SF-36 scores (over 30 point … scores described in Table 6 of the draft report as well as in the studies reviewed above were easily large … changes seen in several randomized AAD trials.(10,11,12) We believe the nonrandomized evidence showing large

371. Omega-3 Fatty Acids and Maternal and Child Health: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
     October 01, 2016 - and a consistent finding of no effects of prenatal maternal supplementation with EPA+DHA among a large … One large observational study on ASD was identified; women with the highest quartile of total PUFA intake … The effect size for the increase in gestational length may not have been large enough to translate to … Observational studies often corrected for a large number of potential confounders, but many important … The findings of large cohort studies are still needed to assess the potential role of n-3 FA status

372. Methods Guide for Medical Test Reviews Chapter 12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
     July 01, 2012 - Large cohort studies and secondary analyses of clinical trials may contain the most readily available … Conclusion There is a large and rapidly growing literature about prognostic tests. … • A large number of published reports focus on the associations between prognostic indicators and

373. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
     March 15, 2010 - patients with OSA; thus, in most patients, the condition remains undiagnosed and untreated.6 There is a large … Public Comments The large majority of public comments regarding the key questions were either answers … Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based

374. AHRQ Slide Template-Widescreen
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-maternal-health-grand-rounds-slides.pptx
     January 01, 2023 - HBPM): Strengths and Limitations Strengths Other HBPM programs have been evaluated in a NRCS and in large … discharged on labetalol may have higher rates of unplanned readmission than those discharged on nifedipine Large

375. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
     June 01, 2010 - Individual cases with large aggregate dosages included both hemophilia and non- hemophilia cases. … cases who were dispensed very large doses. … Individual cases with large aggregate dosages included both hemophilia and non-hemophilia cases. … Unfortunately, the two large, randomized controlled trials on the efficacy and safety of rFVIIa in … Given the large number of figures, the report presents several figures in a size that is smaller than

376. Noninvasive, Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
     September 20, 2017 - Across the conditions and interventions, the literature base is large and complex, which poses another … Large/substantial effects were defined as greater than moderate. … update for journal publication; this will enhance analytic efficiency for this condition given the large … Non-English Language Studies: We will restrict inclusion to English language articles, given the large … There are also situations where the observational evidence may be upgraded (e.g., large magnitude of

377. Urinary-Incontinence-Treatment Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-treatment_research-protocol.pdf
     September 30, 2010 - Previously published reports need to be updated with evidence from the large number of new publications … They have serious errors in design, analysis, or reporting; large amounts of missing information; or … Large observational cohorts based on national registries, population-based surveys, population-based … Issues in comparisons between meta-analyses and large trials. JAMA 1998; 279:1089-93. 72. … interval 2−9) Daily leakage or drops (~17 g/24 hours, 95% confidence interval 13−22) Leakage of large

378. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
     December 01, 2011 - The review focuses on adult patients because adults, and particularly elderly adults, carry the large … Moderate-strength evidence from one large, high-quality study demonstrated that vancomycin and fidaxomicin … Fidaxomycin versus Moderate One large, high-quality RCT deomonstrated decreased vancomycin recurrence … Antibiotic-associated diarrhea accompanied by large-scale alterations in the composition of the fecal … Management and control of a large outbreak of diarrhoea due to Clostridium difficile.

379. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
     January 01, 2012 - The evidence base for PRP lacks large, blinded, prospective, randomized, controlled trials. … first-line therapy and actually regenerate joint cartilage and restore function, it would have a large … However, some of the experts stated that large, randomized, double-blind trials are needed to better … In general, the experts thought that tofacitinib would not make a large shift in how RA is treated or … Experts all thought tofacitinib would have a large impact on costs, but diverged in how the impact

380. Noninvasive Testing for Coronary Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
     January 15, 2015 - A large proportion of ambulatory health care visits are for evaluation of patients with suspected CAD … detect outward remodeling of the coronary artery, which may present a situation in which there is a large … Non-English Language Studies: We will restrict inclusion to English language articles, given the large … There are also situations where the observational evidence may be upgraded (e.g., large magnitude of … complete blockage of the coronary artery resulting in a prolonged period of ischemia; it affects a large