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Total Results: 1,445 records

Showing results for "large".

321. Protocol Amendment - Safety of Vaccines 030413 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
     September 18, 2012 - are unique when compared with many other drugs and medications because they are administered to a large … Although multiple large studies have confirmed the lack of association between MMR and autism, parental … Vaccinations recommended by the Centers for Disease Control and Prevention (CDC) in 2011 are listed in the large … The unanticipated large volume of existing studies on vaccine safety prohibits us from going beyond

322. Microsoft Word - cognitive-decline-protocol-160322.docx (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_research-protocol.pdf
     March 22, 2016 - A large portion of the studies evaluating the effectiveness of interventions in preventing incidence … The volume of all such studies would be overwhelming but some large trials may shed important light … Study Design For KQ1-­2:  RCTs and  large  prospective  cohort studies with  comparator arms (n>250   … For KQ3: large  prospective  cohort studies (n>500) Outcomes Cognitive  decline  measured  with  validated

323. Comparative Effectiveness of Coronary Bypass Surgery and Percutaneous Coronary Interventions for Multivessel Disease: A Pooled Analysis of Individual Patient Data from Ten Randomized Trials (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
     February 01, 2010 - repeat procedures) have been compared in several randomized clinical trials1- 12 and in analyses of large … This possibility has been difficult to assess because no randomized trial has been large enough to … This result was not universally accepted, since analyses of large clinical registries did not confirm … multivessel coronary artery disease after surgical or percutaneous coronary revascularization: Results of a large

324. CER 221 Disposition of Comments: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-comments_0.pdf
     October 11, 2019 - Accordingly, conclusions regarding lack of difference in these endpoints are likely to be limited by large … Are such differences sufficiently large to preclude meta-analysis? … Peer reviewer #6 General Comments The report clearly represents a heroic effort and summarizes a very large … On page 21, line 14, the large font and bolded sentence starting with “Inhaled Budesonide 40 mg…. “

325. Diagnosis and Management of Obsessive Compulsive Disorders in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ocd-protocol.pdf
     August 15, 2023 - However, if we find comparisons with two studies, both of which are large (N≥100) and neither of which … have insufficient evidence to allow for a conclusion (with the exception that a single particularly large … Creating enriched training sets of eligible studies for large systematic reviews: the utility of PubMed's … Creating enriched training sets of eligible studies for large systematic reviews: the utility of PubMed's

326. Disposition of Comments Report for Decision Aids for Cancer Screening and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-decision-support-tools_disposition-comments.pdf
     December 23, 2014 - During the extensive discussions with the TEP members and given the large variety of the assessed study … Our rationale behind that choice (made among the very large number of potential subgroup analyses) … Edited as suggested Peer Reviewer #1 Results In their Abstract, the authors state: `There were no large … `No large` implies an opinion, not a fact.

327. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
     February 01, 2013 - amount of evidence is small to confirm the presence of bias, the potential for bias is possibly quite large … Exclusion of all low quality studies or those at high risk of bias may exclude large body of consistent … framework) as outlined in the chapter of grading the strength of the evidence.19 When there are a large … The assumption is that not employing such limits would yield a very large number of studies that would

328. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
     December 01, 2011 - When a large preponderance of data available for an outcome was of good quality, the strength of evidence … All of these were strategies to enhance the power to detect differences between groups, but by and large … - Even if the trials are not large enough to determine efficacy in subgroups (e.g., sex, age, ethnicity … - Even if the trial is not large enough to determine efficacy in subgroups, such data should be included … Safety of AngioJet thrombectomy in acute ST-segment elevation myocardial infarction: a large, single-center

329. Abnormal-Uterine-Bleeding Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
     November 21, 2011 - Question 2, we will also include data from uncontrolled observational studies, namely high-quality, large … , including varying prevalence of cyclic and irregular patterns of abnormal uterine bleeding, the large … those noted for Key Question 1A and Key Question 1B and uncontrolled observational studies (e.g., large … 2) breadth and specificity of study populations ranging from teens to perimenopausal status; 3) large

330. Disposition of Comments for Quality Improvement Interventions To Address Health Disparities (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_disposition-comments.pdf
     August 27, 2012 - We revised the statement from “Despite fairly large studies in diverse areas of the United States, … Say “The literature on ... health care is large. … strike me as large. … We have further acknowledged the large QI literature that demonstrates benefit generally. … For example, are large disparities seen in conditions such as cystic fibrosis?

331. Implementation of Recommended Screening and Counseling Interventions to Prevent Mental Health Disorders in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/screening-counseling-interventions-protocol.pdf
     October 01, 2023 - We may employ Claude 2 (Anthropics), an advanced large language model, to assist us in extracting descriptive … For data extraction, we will use Claude 2 (Anthropics), a large language model, to support us with extracting … Data extraction for evidence synthesis using a large language model: a proof-of-concept study. medRxiv

332. Disposition of Comments for CER 159 Insomnia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
     December 30, 2015 - At the bottom of page 43, the review also acknowledged that ‘a large proportion of drug trials’ were … Saw a 2008 review in JGIM (Buscemi) which did include a large RCT comparing No trial evaluating trazodone … then fragmented within each treatment (e.g., pattern of administration within each drug), so that no large … We also expanded our search for data on adverse effects by searching for large, longterm, observational … Given that the large majority of investigators and clinicians will not read the entire paper (and many

333. Disposition of Comments Report for Evidence Report/Technology Assessment No. 214 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
     February 25, 2014 - Although all rates are based on patient reports, the Report totally ignores the very large “Non- Disclosure … Reviewer 4 (TEP) Introduction Background: The Report should read: “Multiple studies of large, representative … Large percentages of patients report on entry, during, and after pregnancy that they are not smokers … The EPC prefers to include good quality, large, studies adequately powered to detect meaningful differences … evaluation methods and data specific documentation that the SCRIPT Program was/can be delivered to a large

334. Methods-Guide-Chapter-Prioritization-And-Selection-Of-Harms-For-Inclusion-In-Systematic-Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
     February 01, 2018 - and function), different interventions given for the same condition are frequently associated with a large … controlled trials, observational studies (including pharmacoepidemiological studies performed on large … that it was difficult to apply a maximum threshold for harms to be included in EPC reports, given the large … Given the large number of interventions and comparisons that may be included in an EPC review, the number … • Patient incorporation has been a large focus.

335. Disposition of Comments for Interventions for Adolescents and Young Adults With Autism Spectrum Disorders (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
     August 27, 2012 - more in a concluding sentence that only five studies of fair quality have been done concerning this large … other hand there is a growing movement and literature on how RCT’s are not the only away to evaluate large … with such a lack of high quality research in this area, it is difficult to make the argument that large … account for typically smaller study sizes in ASD research while including studies with sample sizes large

336. The AHRQ Evidence-Based Care (EBC) Challenge (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ebc_challenge_faq.pdf
     January 01, 2010 - I work for a large organization or company. Can we brand the materials?

337. TND-0775-150722 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
     May 12, 2015 - non-pharmacological treatments for adults with schizophrenia, a scan of the literature identified a large

338. Management of Infantile Hemangioma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_policymaker.pdf
     June 01, 2016 - causes pain, ulceration, and bleeding; and »» children whose IH causes significant disfigurement (e.g., large

339. Hip-Fracture-Pain Clinician (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
     May 01, 2011 - . �� Multicenter research studies are needed that are large enough for statistical analysis of subgroups

340. Gastric-Cancers-Supplementary-App-I (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-i.xlsx
     January 01, 2019 - Probably decrease Although only one effect modifier considered for adverse events, a large number (25 … Probably decrease Although only one effect modifier considered for adverse events, a large number (25