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Showing results for "large".

261. Template for Reports Developed (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-nomination_methods.pdf
     November 01, 2012 - and health care system, (3) are not already covered by a high-quality review, 3 (4) represent a large … Represents a significant disease burden; large proportion or priority population 2b. … Is of high public interest; affects health care decisionmaking, outcomes, or costs for a large proportion … Are there any large ongoing trials that would impact the timing of a review on the topic? … For example, there may be large, in-process clinical trials whose results will heavily influence any

262. Research White Paper Registries in Accountable Care Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/accountable-care-registries-guide-3rd-ed-addendum-white-paper-2018-5.pdf
     January 01, 2018 - For example, the Medicare Pioneer ACOs are typically large, integrated systems, several of which participated … The stakeholder group may be large and diverse, particularly if the registry is intended to meet multiple … The Cleveland Clinic Health System, a large multi-specialty academic medical center with over 3,000 … To develop the registry, Cleveland Clinic organized a large stakeholder group, including representatives … Structured Query Language (NoSQL) databases using technology solutions such as, Hadoop, to manage large

263. Stem-Cell-Children Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
     February 01, 2012 - optional domain, strength of association (magnitude of effect), was used in this process where a large … certain mortality in infancy, so that even very small case examples of survival or cure suggest a large … autoimmune juvenile diabetes can be managed long term satisfactorily, at relatively low risk, in a large

264. Mrsa-Screening-2010 Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
     January 01, 2010 - patients with asymptomatic carriage of antibiotic-resistant organisms such as MRSA, there exists a large … SOE was raised by one level based on the large effect size but lowered one level based on the high risk … This approach reduces the bias associated with even large multicenter observational studies. … However, cluster RCTs may also face barriers to feasibility due to the large number of institutions … Thus, large multicenter trials will be needed.

265. Comparative Effectiveness Review No. 258_Diagnostic Errors in the Emergency Department: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diagnostic-error-executive-summary.pdf
     August 01, 2023 - • Variation in diagnostic error rates across demographic groups is present and sometimes fairly large … Results for Key Question 1 relied heavily on two large studies (one of medical malpractice claims, the

266. Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_executive.pdf
     January 01, 2020 - Although multiple large studies have confirmed the lack of association between MMR and autism, parental … Large- scale epidemiological studies could determine other patient risk factors. … Large datasets from U.S. managed care organizations include medical records on both immunization and … The need for large numbers of pregnant exposures is particularly important given the relatively low … In the United States, the VSD contains data obtained through such systems at nine very large managed

267. Disposition of Comments: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diverticulitis-comments.pdf
     October 12, 2020 - analyses demonstrates that they chose only systematic reviews, randomized controlled trials, and large … While the summary statements were designed for brevity, a large Appendix (D) was provided including

268. S58 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
     October 01, 2007 - A key strength is the very large number of individuals represented and corresponding statistical power … Very large datasets can be obtained and updated for a fraction of the cost of comparably sized studies … Medicaid Claims Data Dataset Characteristic Comparative Advantages and Types of Studies Supported Very large … Dataset development not constrained by per-subject costs of primary data collection; large, comprehensive … However, ef- fective use of these powerful but large and complex datasets is labor-intensive, requiring

269. Assessing the Impact of Indexing Performance Measure Codes on the Perceived Value of EPC Reports to Health Systems (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-assessing-impact.pdf
     September 01, 2018 - Our initial enhanced quality measure tables were well regarded by four representatives of a large academic … Results Our initial enhanced quality measure tables were well regarded by four representatives of a large … Results In the phase one assessment, the key informants from the Duke University Health System, a large … not have an extensive number of health systems in our pilot project but we did have insight from a large … take approximately 30 to 50 hours of effort to create this enhancement in projects of moderate to large

270. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
     January 01, 2015 - Retrospective cohort studies and large data base studies are clearly of lesser validity with respect … Even though ADOPT was large and long, losses to followup were massive and differential (more in the … AHRQ is experimenting with alternative report formats, including having multiple reports for large … AHRQ is experimenting with alternative report formats, including having multiple reports for large … In this context, discussion of how such a study might be designed and how large it would need to be

271. Management of Infantile Hemangioma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
     June 01, 2016 - ulceration, and bleeding; and �� patients with IH that causes significant disfigurement (e.g., large … ��The narrative review of the literature suggested that indications for referral include large lesion

272. Dispostion of Comments Report for Child and Adolescent Exposure to Trauma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_disposition-comments.pdf
     February 11, 2013 - Overall the report demonstrated the large gaps in knowledge, the small sample sizes, the lack of replication … measures of benefits and low or moderate risk of bias with regard to benefits would appear to exclude a large … child trauma interventions rather than relying on summarizing RCTs in this field because conducting a large … number of very expensive RCTs with sufficient number of participants for the large number of distinct … Alternative approaches would include systems for monitoring and reporting on the large number of uses

273. Amended Protocol: Maternal and Childhood Outcomes Associated with the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/wic-outcomes-nutrition-protocol-amended.pdf
     October 01, 2020 - complications, morbidity and mortality Infant birth outcomes: e.g. gestational age, birth weight, small/large … there are substantial differences between the N of two comparison groups or arms, or effect size is large … continuity correction.12 We will use Cohen’s classification to categorize effect sizes as small, medium or large … birth weight Low birth weight, Normal birth weight High birth weight Small for gestational age Large

274. Antiplatelet-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_executive.pdf
     September 01, 2013 - The 106 studies had intermediate to large sample sizes: median number of enrolled individuals = 277, … Because of the large differences in included populations, treatments compared, and exposure and outcome … Results from large randomized trials assessing effect modification by CYP2C19 variants on MACE Note … Five were based on large randomized trials of clopidogrel-based therapy that included more than 1,000 … Studies of treatment-effect modification by CYP2C19 genotype were based on large randomized trials,

275. S96 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
     October 01, 2007 - selected to repre- sent a range of ADE reporting (0.2–1.7% of ED visits) and a range of bed sizes (3 very large … , 1 large, 1 medium, and 1 small). … Large metropolitan (1 hospital), smaller metropolitan (3 hospitals), and rural areas (2 hospitals) and … , the system captures ADEs treated in a wide spectrum of outpatient healthcare settings (eg, EDs in large

276. Microsoft Word - ehcrr#2toCSI.doc (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
     August 01, 2007 - Linear regression to estimate risk difference is valid in large samples like ours.32 Because patient-level … than atypical APM users in multivariable adjusted models of 180-day mortality that controlled for a large … Sensitivity analyses revealed that very large relative risks of 5 or greater would be needed linking … We found that large imbalances of risk factors among the actual treatment groups (Table 1), were substantially

277. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
     September 01, 2011 - We experimented with several different approaches for presenting the large amount of data pertaining … Unfortunately, resources for large good qulaity studies just do not exist, and therefore it's likely … Another large hurdle that our subspecialty is facing. … The section regarding future research is right on target, especially the large cohort studies that are … This report is very timely and will likely result in future work that will hopefully close this large

278. Covariate Selection for Observational Comparative Effectiveness Research
     effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
     January 01, 2013 - Since comparative effectiveness research studies will need to consider potential confounding from a large … Since comparative effectiveness research studies will need to consider potential confounding from a large … Propensity Scores Propensity scores are an increasingly common analytical strategy for adjusting for large

279. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
     February 19, 2010 - after treatment.22 Recanalization rates vary depending on the site of the occlusion, with events in large … thrombolysis including: more rapid achievement of recanalization vs IV rtPA; enhanced efficacy in treating large … “for use in the revascularization of patients with acute ischemic stroke secondary to intracranial large

280. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
     May 19, 2010 - Outcomes: All reported side effects and adverse events will be abstracted from clinical trials and large … Next, by using data from clinical trials and large cohort studies, evidence of benefits and harms in … Efficacy studies are frequently conducted in large tertiary care or referral settings. 4.