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Total Results: 1,445 records

Showing results for "large".

221. Disposition of Comments: CER 230 Therapies for Clinically Localized Prostate Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-230-prostate-cancer-comments.pdf
     September 17, 2020 - • In general the peer review and TEP comments were very supportive with the large majority rating

222. Disposition of Comments for Psychological Treatments and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
     April 03, 2013 - on inpatient units, in residential treatment, in day programs—are left out of the literature by and large … of this report so we did not want to expand this text too much in a report that is already very large … Due to the already large scope of this review, it was important that we focus on the most clinically … There were a large number of interventions, comparisons, and outcomes included in the report. … We realize that the full report is a large document with copious information; the executive summary

223. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
     June 01, 2017 - LMWH versus antiplatelet drug (aspirin): One very large NRCS (N=108,584) and another smaller NRCS ( … In both adjusted and propensity- score matched analyses, the very large NRCS found no differences in … A large volume of evidence has been garnered comparing intervention options to prevent VTE in patients … The large majority of studies compared different intervention classes (relevant to Key Question 1), … Based primarily on a very large, well conducted observational study (with propensity score analyses)

224. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
     June 01, 2017 - LMWH versus antiplatelet drug (aspirin): One very large NRCS (N=108,584) and another smaller NRCS ( … In both adjusted and propensity- score matched analyses, the very large NRCS found no differences in … A large volume of evidence has been garnered comparing intervention options to prevent VTE in patients … The large majority of studies compared different intervention classes (relevant to Key Question 1), … Based primarily on a very large, well conducted observational study (with propensity score analyses)

225. Rapid Evidence Product_Assisted Home Dialysis in the United States: New Interest in an Old Idea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/home-dialysis-ESKD-rapid-research.pdf
     April 01, 2025 - experts who were clinically familiar with assisted home dialysis and are involved in administering large … That goal remains elusive despite large scale policy initiatives including new Medicare payment models … Evaluating Factors Contributing to Dropout in a Large Peritoneal Dialysis Program. … Non-U.S. studies were prioritized if they were large, multicenter studies. … • What about in large health systems like the VA? 3.

226. Methods Guide for Medical Test Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
     July 01, 2012 - studies do not vary widely, or (2) the sensitivity and specificity of various studies vary over a large … the second type of situation, when the sensitivity and specificity of various studies vary over a large … downward slope (from left to right) was observed in approximately one out of three meta-analyses in a large … There is no empirical evidence on the performance of either model in a large number of applied examples … • If the sensitivity and specificity vary over a large range, it may be more helpful to use a summary

227. Machine Learning Methods in Systematic Reviews: Identifying Quality Improvement Intervention Evaluations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/machine-learning-quality_research.pdf
     September 01, 2012 - Screening large search outputs is a lengthy process requiring considerable reviewer resources for a … Electronic search strategies for quality improvement are particularly challenging, producing large … In addition, outcomes are often institution and intervention-specific and can also encompass a large … The performance data for the remaining large dataset compared with reviewer screening of selected … Large-scale Bayesian logistic regression for text categorization.

228. Disposition of Comments Report for Evidence Report 215 Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
     January 01, 2020 - A reliable system of determining when in pregnancy ( large populations of pregnant women) the vaccine … The overall conclusion seems to be that more large-scale epidemiologic studies are needed to assess … TEP # 1 Research Gaps—Page 130 line 8-9 Delete: “Large scale epidemiological studies are needed to … The results are meaningful, and the tables help to summarize the large amount of data. … However, a large U.S. study found no association.

229. CER 244 Evidence Summary: Safety of Vaccines Used for Routine Immunization in the United States: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-vaccines-update-evidence-summary.pdf
     May 01, 2021 - Despite the large literature, there remains insufficient evidence for rare potential adverse events … for which very large samples would be needed to estimate the risk or to definitively exclude a risk … Conclusion Across this large body of research, we found no new evidence of increased risk since the

230. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
     September 01, 2009 - A large amount of observational data, as well as clinical trials, support a significant, modifiable role … combination, including statin-omega-3 combination, which was studied in three trials, one of which was a large … One large statin- omega-3 trial of 18,645 Asians demonstrated no significant difference between treatments … However, one large 5-year trial investigating various statins in both treatments among 18,645 Asians … Only one large statin-omega-3 trial can be considered an effectiveness trial; however, this trial examined

231. Disposition of Comments for Interventions for the Prevention of Posttraumatic Stress Disorder (PTSD) in Adults After Exposure to Psychological Trauma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
     April 02, 2013 - As PTSD only became an official diagnosis in 1986, it is not surprising that large well-controlled prevention … for the authors to explain why this single-study was given a different determination (was there a large … and state-of-the-art clinical efforts in this area have moved beyond universal prevention based on a large … there may be robust but somewhat less restrictive criteria that might be employed to capture the large … ES-1) Although exposure places people at risk, this statement overlooks a large and robust literature

232. Disposition of Comments for CER 147 Menopausal Symptoms: Comparative Effectiveness of Therapies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
     March 05, 2015 - The caterpillar plots were a particularly effective way to clearly summarize large amounts of information … and bias, as noted in the methods we imposed one departure to the downgrading in the presence of a large … physicians are increasingly withholding estrogen from these women, jeopardizing the health of this large … In the presence of a large number of trials (n > 10), even when a majority of the trials were rated … The authors have done a commendable job in synthesizing a large and complex body of literature.

233. Microsoft Word - finbody.doc (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
     January 01, 2007 - cohort studies of medical interventions, cohort studies of RAS natural history, and prospective or large … • There is acceptable evidence that combination antihypertensive treatment results in large decreases … It should be sufficiently large to cover a range of ARAS severity, including percent stenosis, percent … In contrast, among patients with bilateral disease, there was a large decrease in blood pressure (–24 … • Although studies were generally too small to detect any but large differences in mortality rates

234. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
     February 01, 2015 - In early 2014, results from a large phase III clinical trial indicated that citalopram was more effective … insulin administrations on cognition and neuroanatomy, is scheduled to conclude in February 2015.12 A large … investigating intranasal administration of Humulin R for treating cognitive symptoms of AD.12 An additional large … One expert, however, concluded that this intervention could have a large impact on health disparities

235. Disposition of Comments for Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non-Small-Cell Lung Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_disposition-comments.pdf
     June 12, 2013 - This has been reported in published single-arm studies reviewed in this CER, for example the large, … the order of the subtypes of non-small cell lung cancer to adenocarcinoma, squamous carcinoma and large … We changed the order to “adenocarcinoma, squamous cell carcinoma, and large cell carcinoma” as suggested … It is unclear to my why only 1 study was analyzed for RFA when there are large studies that focus on … This has been reported in published single-arm studies reviewed in this CER, for example the large,

236. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
     December 14, 2010 - LAGB is a less complex procedure as compared to RYGB and it produces weight loss, but may not have as large … First, by using data from clinical trials and large cohort studies, evidence of benefits and harms of … from related topic projects Our literature search will focus on identifying controlled trials and large … procedure in which the stomach is reduced to about 15% of its original size, by surgical removal of a large

237. S50 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
     October 01, 2007 - Over 20 large, multicenter PBE-CPI studies using CSI have been conducted. … Analyses Detailed data are captured in PBE-CPI studies to create a large study database that includes … cannot be assigned, alternate hypotheses regard- ing possible cause and effect can be tested using the large … However, the large natural variation encountered in current practice within and between facilities affords

238. Ch 10-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
     January 01, 2011 - Propensity scores are appropriate when adjusting for large numbers of covariates and are particularly … Since CER studies will need to consider potential confounding from a large number of study covariates … Propensity Scores Propensity scores are an increasingly common analytic strategy for adjusting for large … Large sample properties of matching estimators for average treatment effects.

239. Disposition of Comments Report for Procalcitonin-Guides Antibiotic Therapy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
     October 05, 2012 - Scheutz) of the ProHOSP study has also publicly stated the need for a large US confirmatory trial. … The large study reported an effect larger that the pooled effect (-3.0 days), while the 2 smaller studies … and appropriately note that definitively determining a mortality difference would require a very large … and standard therapy and have a confidence interval that is narrow would require a large sample size … ill patients and variability in mortality of sepsis patients limits researchers’ ability to enroll large

240. Treating and Preventing C. difficile Infections (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_consumer.pdf
     May 01, 2017 - infection (CDI) results from a type of bacteria (or germ) called Clostridium difficile infecting your large … When this Large Intestine C. difficile bacteria Small Intestine happens, bacteria such as C