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Total Results: 1,445 records

Showing results for "large".

181. Kidney-Disease-Medicine Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
     January 01, 2012 - A recent series of meta-analyses of large prospective cohort studies demonstrated the independent associations … not identified through a comprehensive literature search, whenever possible we evaluated data from large … routinely tested for CKD, especially for albuminuria, systematic screening likely would lead to a large … • Determine eGFR and albuminuria from baseline and followup blood and urine available from large … • Merge data from large-scale treatment RCTs with Medicare data to identify incident ESRD cases

182. Disposition of Comments CER 214 Stroke Prevention in Patients With Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
     October 30, 2019 - Given the large number of comparisons and key points we have not added in the quantitative information … We provided greatest weight to findings from large RCTs.” 32. … Peer Reviewer #6 Methods p. 43—I am not sure that having a large number of studies means there is no … Large interaction p-values do not provide evidence for similarity. … Apixaban is the only agent that has been studied in a large RCT in these specific patients.

183. Disposition of Comments Report for CER 207 on PTSD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-207-ptsd-disposition-comments.pdf
     May 17, 2018 - For bodies of evidence with 3 or 4 studies and large heterogeneity, we comment on why findings were … If, however, a body of evidence does not show a large amount of heterogeneity, I think it would be … A "statistically significant" result, p<.05, merely means that the sample size was large enough to … No matter how small the deviation, there is always a sample size large enough to give 80% power of … We did not accept any study designs other than RCTs (and large observational studies just for KQ4,

184. Fraenkel (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/fraenkel.pdf
     May 29, 2025 - backgrounds • More efficient than rating scales • < social desirability or extreme response • Can handle large

185. S16 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
     October 01, 2007 - practice-based research networks and electronic health records will make it increasingly feasible to conduct large … meta-analysis is more powerful for this purpose, and has been used with success in several areas with large … Administrative database Estimates of major harms across large populations; detection of rare events; … of a surgical intervention, to illustrate how this approach can add to the information from a single large … endarterectomy to prevent stroke in patients with asymptomatic carotid stenosis was addressed in a large

186. Appendicitis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
     December 01, 2015 - involve ionizing radiation (e.g., CT) entails greater risks for children than for older patients.20 A large … CT (0.92 vs. 0.91), but CT had greater sensitivity (0.89 vs. 0.96); these results were based on a large … CT has been investigated in a large number of diagnostic cohort studies, leading to precise estimates … • In contrast to the RCTs, NRCSs of alternative testing strategies attained large sample sizes but … 1.67 Under these conditions, RCTs comparing alternative test strategies would need to enroll very large

187. Ch-7-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch-7-user-guide-to-ocer_130129.pdf
     March 29, 2012 - vaccines, and screening tests.8 Environmental and Social Factors Access to health care: Within large … In practice, where observational studies include large multi-use databases spanning vast geographic … not thousands, of data points that are recorded for clinical and administrative purposes.64 These large … for unmeasured confounders, Schneeweiss and colleagues proposed an algorithm that creates a very large … Estimating causal effects from large data sets using propensity scores.

188. Grading_didactic_faculty_approved (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
     January 01, 2010 - approach used by the Evidence-based Practice Centers (EPCs) to grade strength of evidence is based in large … Even if the study is a large multicenter trial (i.e., a mega-trial), findings from different centers … Thus, EPC reviewers cannot be certain that a single trial, no matter how large or well designed, presents … Magnitude of effect: Defined as the likelihood that the observed effect is large enough that it cannot … Two scores are possible for strength of association: Strong: large effect size that is unlikely to have

189. EHC Research Protocol: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
     January 01, 2019 - diverticulitis is caused by inflammation of abnormal outpouchings (diverticula) in the wall of the large … Complications are mostly caused by small or large perforations to the diverticula, which may introduce … This process will make screening more efficient and will enable us to capture the large majority of … [Prognostic factors in perforating diverticulitis of the large intestine]. … intestine Diverticulosis presence of diverticula (outpouchings) of the wall of the large intestine

190. Maternal and Fetal Effects of Mental Health Treatments in Pregnant and Breastfeeding Women: A Systematic Review of Pharmacological Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
     December 05, 2018 - Results from a large epidemiological survey in the United States offer indirect evidence on rates of … Observational cohort studies, particularly large birth cohorts such as the Norwegian Mother and Child … Cohort Study33 and the Danish National Birth Cohort,34 capture sufficiently large samples to assess … Large administrative databases35, 36 allow assessment of rare outcomes such as congenital anomalies … related to treatment o Death • Fetal/infant/child harms o Preterm birth/small for gestational age or large

191. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0193_08-12-2009.pdf
     January 01, 2009 -  Because of the importance of this topic, the current state of the literature, and the large

192. Antibiotics-Respiratory-Infection Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
     January 01, 2016 - Given the large number of interventions to consider, those with insufficient evidence are not discussed … For example, rapid strep testing for sore throat has moderate-strength evidence of large reductions … Delayed prescribing (any method) resulted in moderate-strength evidence of large reductions in use of … Reasons for these differences include the addition of a large volume of newer evidence, the use of a … The evidence of potential increased risk comes largely from three trials: a single, large (N = 4,264

193. Methods Guide for Medical Test Reviews - Editorial (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guide-editorial_methods.pdf
     July 01, 2012 - literature to patient care by critically appraising and summarizing what is often, for a given topic, a large … differs from published standards of care, clinical guidelines differ in their recommendations, and a large

194. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
     September 01, 2011 - First, Elliott3 and Perry4 both deal with adverse effects, have large numbers (9357 and 8709), (respectively … does not express a scientific rationale for including non-comparator studies except that they are large … can raise our confidence above low (or insufficient) – And that is only when the study (ies) is of large … sample size, is rated as low risk of bias and demonstrates a very large effect size for a clinical

195. Critical Analysis of the Evidence for Patient Safety Practices in Nursing Home Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nursing-home-safety_research-protocol.pdf
     July 22, 2015 - Early and ongoing research has focused in large part on the use of secondary data analyses, rather than … This secondary analysis typically includes data from across a large number of NHs and largely reflects … Small versus large institutions e. Particular vulnerability of the residents f. … Published Literature search A large number of systematic reviews have been published in this area.

196. Association Between Outcomes and Dental Services in People Receiving Treatments That Cause Medication-Related Osteonecrosis of the Jaw: A Rapid Response Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-jaw-rapid-response.pdf
     May 01, 2025 - • Four large retrospective cohort studies of fair quality demonstrated a statistically significantly … Data from four large retrospective cohort studies showed statistically significantly increased risk … from large databases (LHID in Taiwan, NDB in Japan, NHIS in 4. … Four large database studies offered analysis with statistical power to assess rare events like MRONJ … Since MRONJ is a rare condition (0.2 – 0.3% prevalence in the treated non-cancer population),63 large

197. Covariate Selection for Observational Comparative Effectiveness Research
     effectivehealthcare.ahrq.gov/sites/default/files/covariate-selection-chapter-7.pptx
     January 01, 2013 - Environmental and Social Factors Access to health care Within large populations analyzed in multiuse … often employed for this purpose; they can be used in health care epidemiology to statistically control large … Estimating causal effects from large data sets using propensity scores. … selection approaches Automatic high-dimensional “proxy” adjustment An algorithm that creates a very large … Covariates are entered into propensity score models where statistical control of a large number of covariates

198. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
     June 01, 2010 - interventions, there is widespread agreement that observational studies, particularly those derived from large … In Table 2, example 5, a large number of head-to-head efficacy trials were available, but they provided … Well-known or large RCTs should be examined in detail at this stage. … The review also included 96 articles reporting findings from 10 large cardiovascular registries. … clinical question of antioxidant supplementation to prevent heart disease has been studied in numerous large

199. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
     June 01, 2010 - interventions, there is widespread agreement that observational studies, particularly those derived from large … In Table 2, example 5, a large number of head-to-head efficacy trials were available, but they provided … Well-known or large RCTs should be examined in detail at this stage. … The review also included 96 articles reporting findings from 10 large cardiovascular registries. … clinical question of antioxidant supplementation to prevent heart disease has been studied in numerous large

200. Methods Research Report Improving Access To And Usability of Systematic Review Data for Health Systems Guideline Development (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-health-systems-guidelines-development.pdf
     February 01, 2019 - February 2019 ii Key Messages Purpose of Project Identify and test interactive methods to make the large … may impede understanding and use in decision processes, but little evidence exists on transforming large … this “proof-of-concept” prototype development demonstrate that existing tools could be used to make large … Systematic reviews provide a large volume of data that can be used by decision makers in these health … Objective Our objective was to identify and test interactive methods to make the large amount of data